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Any Post-Treatment Reflections? 8 years 1 month ago #9775

ps My very best wishes to everyone ending treatment for the very best results #love
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 'In the slow lane'
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
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Any Post-Treatment Reflections? 8 years 1 month ago #9786

I am finishing treatment also in 2 days and the best thing has been that i was UD by week 4 . I have had a lot of trouble with weakness, tired all the time and have the dreaded brain fog. The headacres that i had for the first 2~3 weeks stopped once i drang plenty of water but the other symtoms are still there only not as severe. I am concerned as to how much better I feel once TX is over this week and so will post how I am feeling as the weeks pass. I hope more do this as I think this is a concern for those just starting or those in the middle of TX.
Good luck everone!!!
Genotype1b probably since 1978.
On prior TX. Started TX 11nov15
Sofosburvir + Daclatasvir FixHepC
VL Undetected 4weeks thanks to
Dr Freeman and FixHepC
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Any Post-Treatment Reflections? 8 years 1 month ago #9787

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I finished my 12 weeks on Jan 21 though I am doing an extra 4 weeks and will be done in about
2.5 weeks.

I'm happy I did it, I feel better and I am relieved I made the decision its great to know the virus is
gone. Oh, I had no side effects what do ever I have being very lucky.
Sob/Dac from Oct 29 2015
Geno 1b
Fiberscan 9.9 Pre treatment
Fiberscan 7.4 week 10
VL 1.3 million pre treatment
Week 2.5 VL 96
Week 5.5 VL 17
Week 10 VL UD
SVR 3 UD
SVR 16 UD
Cured:
All liver functions in normal ranges.
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Any Post-Treatment Reflections? 8 years 1 month ago #9790

Lynne-Francis-facebook wrote: Hi Not sure if this is the right place to be for my question...I have five days to go before I finish treatment. The past week I have felt incredibly down and unhappy....not my usual demeanor......very teary. Very anxious about my post 12 week blood test....not sure if it is maybe being anxious about the result...... :( Has anyone else experienced this?


Hi Lynne, I am not far off finishing TX as you mention you are, I too have had nagging thoughts and all kinds of anxieties around stopping taking the meds. I have a slight chemical taste in my mouth and can't wait for that to go away but part of me doesn't want to stop taking the sof/dac ever. I wan't to get VLs done on a weekly basis but know its pointless until 4 and 12 weeks after TX, I think my worry is irrational, and try to hang onto the science which I trust a lot more than my damaged mind, And the depression and isolation as well, the not being able to talk about this with anyone, not being able to express our hopes and fears etc, its a whole psychological burden on its own.

As for nagging symptoms I have a few, but I think I had medical stuff going on way before I was infected with HepC, some gastric and psychiatric issues, an inability to put on weight, excema, depression was probably my worst pre infection issue. So for me, a lot of the issues which I had before infection became amplified by HepC it seems, meaning just because I have cleared(hopefully) the virus I still need to watch my diet(avoid foods I was intolerant of before infection) and watch my mental state to avoid falling back into the pit of depression I lived through during childhood.

I found the best guide to my health is the Bristol Stool Chart, when I am in the middle, I am happy and have energy, as Hippocrates said I think all disease begins in the gut, which goes on to effect the mind and the rest of the body,

A subject no one likes to talk about but its been mentioned by inference in a few posts here,
en.wikipedia.org/wiki/Bristol_stool_scale

When my gut is happy my skin tone improves, I start to sweat again, my BO stinks like it should, and most anxieties go away, but yes I too am quite anxious about the end result, and I am not the best patient. No wonder so many doctors told me I was untreatable, being born with so many allergies did not make early life easy, my poor mom was at a wits end trying to feed me at all. When tested for allergies I was apparently showing reactions to the "control" test, so they gave up trying to figure out what I was allergic to,, just gave me a long list of foods and substances to avoid, almost impossible to adhere to in this world.

So long as I eat right, my gut is happy and so generally is my head. In my case I think I have food intolerance totally unrelated to HepC and so watch my diet very carefully. I can apparently eat a lot of the foods I used to avoid, but choose not to rock the boat so to speak, always my guts are my guide, literally.

As for Tx itself I had virtually no sides apart from disturbed sleep punctuated by lurid and weird dreams, but I guess I normally dream like this and just don't recall the dreams when I sleep more deeply,

Hope this helps somewhat,
good luck and regards
Jim
3 years cured, Sof/Dac, thanks Doc Freeman, hepc only a distant memory, go for it ppl
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Any Post-Treatment Reflections? 8 years 1 month ago #9794

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Lynne-Francis-facebook wrote: Hi Not sure if this is the right place to be for my question...I have five days to go before I finish treatment. The past week I have felt incredibly down and unhappy....not my usual demeanor......very teary. Very anxious about my post 12 week blood test....not sure if it is maybe being anxious about the result...... :( Has anyone else experienced this?


As an interferon relapser I was even scared of starting any new tx...I am scared of relapsing...I am scared of sx, I am scared of a lot of stuff BUT I think this is completely normal.
After all, I realise I have not been well for a darned long time, in my case Lynne, I was not told of any sx going into peg/inf, in fact when I asked I was told about people who 'worked all the way through peg/inf', and how they 'breezed' through it, no no truth was told. I was NOT told about fibroscan and not given one. I am F0! I was urged in fact to commence tx immediately.
I was not gene tested, I was not told about this and when I finally was taken off tx at 43 weeks with heart trouble by a locum while the Gastro person responsible for this failed duty of care was away, I relapsed within four weeks.

These and the last four years of rebuilding my completely destroyed body have made me nervous.

I agree with LG, I have decided to praise myself, and that is; focusing on the triumph of reinventing myself, of taking the bit between this old nags teeth and giving this a go...of never giving up hope, and of just accepting baby steps are my thang.

I asked about relapsing going in, via a pm to Dr James, and I know if the worst happened it is not all lost and done and dusted for any of us. I think that this is a great issue you have raised.

We will be okay. After tx a nice cleansing lifestyle to detox these meds too...lots of swimming in the sea (not very close to Bendigo ;) ) massages, walks, new hobbies, trying something we have never done before...these are great things to distract the mind.

I feel your anxiety, and thank you for the honesty Lynne xxx
Ariel #love #duck #love
Gen 1a
Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas.
pre sof/led VL 240,000 Fibsc F0
Day 25 <30
Day 32 UND
Week 10 UND
EOT UND ALT11AST17GGT19
SVR4 UND ALT10 AST16 GGT13
SVR8 UND ALT <9 AST16 GGT15
SVR12 UND ALT14 AST19 GGT12 Bili 5
EOT +18 ALT13 AST20 GGT9 Bili 5
EOT +21 ALT11AST15
Cured SVR12
Dysplasia Adenomas RemvdAug '16
SVR24 UND ALT11AST16
ColonoscopyClear Nov17
LumpectomyClear ‘18
LithotripsyCytoscopyBiopsy 4/18
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Any Post-Treatment Reflections? 8 years 1 month ago #9833

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Jimmy6429 wrote: As for nagging symptoms I have a few, but I think I had medical stuff going on way before I was infected with HepC, some gastric and psychiatric issues, an inability to put on weight, excema, depression was probably my worst pre infection issue. So for me, a lot of the issues which I had before infection became amplified by HepC it seems, meaning just because I have cleared(hopefully) the virus I still need to watch my diet(avoid foods I was intolerant of before infection) and watch my mental state to avoid falling back into the pit of depression I lived through during childhood.

I found the best guide to my health is the Bristol Stool Chart, when I am in the middle, I am happy and have energy, as Hippocrates said I think all disease begins in the gut, which goes on to effect the mind and the rest of the body,

A subject no one likes to talk about but its been mentioned by inference in a few posts here,
en.wikipedia.org/wiki/Bristol_stool_scale

When my gut is happy my skin tone improves, I start to sweat again, my BO stinks like it should, and most anxieties go away, but yes I too am quite anxious about the end result, and I am not the best patient. No wonder so many doctors told me I was untreatable, being born with so many allergies did not make early life easy, my poor mom was at a wits end trying to feed me at all. When tested for allergies I was apparently showing reactions to the "control" test, so they gave up trying to figure out what I was allergic to,, just gave me a long list of foods and substances to avoid, almost impossible to adhere to in this world.

So long as I eat right, my gut is happy and so generally is my head. In my case I think I have food intolerance totally unrelated to HepC and so watch my diet very carefully. I can apparently eat a lot of the foods I used to avoid, but choose not to rock the boat so to speak, always my guts are my guide, literally.
Jim

Thanks, I'm getting a lot out of reading everyone's experiences and thoughts.
I'm about to end week 3 of Tx tomorrow so have awhile to go yet. But like you Jimmy I have a lot of pre-existing conditions and HepC has definitely exacerbated things - as to how much? I won't really know until EOT/post-Tx. My gene pool has left me with a lot of allergies/food intolerances and hence gut issues. I absolutely agree with how my 'mood' is affected by my gut issues. I've been diagnosed with IBS but I'm also sure the HepC is messing me up more. Severe diarrhoea, that can go for days, unless I take medication - leaves me extremely dehydrated either way. Therefore more headaches, dry skin and mouth, dizzy spells etc. Alternating with constipation, being 'blocked' and bloated for days, makes me really cranky and depressed.
On Tx, my 1st 2 weeks were good, high energy, sleeping solidly, but sweating profusely, liver and kidney pain, sharp stabbing on/off headaches. Emotionally, a roller-coaster ride, very teary at times. But, noticed my usual persistent low grade anxiety isn't there, I have high anxiety episodes still but they resolve faster. Depression still lurking and have had some real lows. Peripheral neuropathy still shocking and swollen painful joints - pre-existing arthritis - seems to flare up badly at times.
I still seem to be having gut issues, can't digest meat properly - I end up with 'pale, floating' stools - sign of not digesting fats well.
I'm still very fatigued though and hope that lifts.

I feel encouraged by those of you who have finished and started out with similar conditions/symptoms and are rid of some and less affected by the rest.
I'm trying to be optimistic but don't want to put too much hope into improving - being 'cured' of the virus won't necessarily mean 'cured' of all conditions - because I'll be like others have mentioned and become anxious or depressed at EOT about 'results'.
Good Luck to those who have finished, are about to and the rest of us with many weeks to go #love #love
QLD Australia ☀️
G3a HCV 35 yrs Tx naive
Started Sof/Dac 13/01/16

Dec '15
AST 70
ALT 89
GGT 124
Fibroscore 8.5
F1-F2
13 Feb'16 VL UND #woohoo!
AST 24
ALT 26
GGT 50H
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Any Post-Treatment Reflections? 8 years 1 month ago #9872

I've been reading this book:

www.amazon.co.uk/dp/B00A3KO1Q6/ref=pe_385721_48721101_TE_M1T1DP
Why Do I Still Have Thyroid Symptoms? When My Lab Tests Are Normal
by Datis Kharrazian

The reason I quote it here is because he dwells a lot on gut issues and the immune system. One of the primary underlying causes he cites for kicking off a whole cascade of malfunction in multiple systems is chronic viral infection. This is the book that joins up the dots.

dt
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Any Post-Treatment Reflections? 8 years 1 month ago #9873

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dointime wrote: I've been reading this book:

www.amazon.co.uk/dp/B00A3KO1Q6/ref=pe_385721_48721101_TE_M1T1DP
Why Do I Still Have Thyroid Symptoms? When My Lab Tests Are Normal
by Datis Kharrazian

The reason I quote it here is because he dwells a lot on gut issues and the immune system. One of the primary underlying causes he cites for kicking off a whole cascade of malfunction in multiple systems is chronic viral infection. This is the book that joins up the dots.

dt


Hashimoto's disease and hypothyroidism are EASILY discovered with blood test. He is saying he DISCOVERED hashi is a autoimmunity disorder? NO he did not! First he is not a real DOCTOR. He is a Chiropractor. He is generating money off his books, speaking engagements, a ton of websites. A intern can diagnose these diseases with blood work etc.
Genotype 1A
ALT 473
AST 226
Virus Load 3,119,030
Results as of May-2016
5 week viral load/undetected as of 12/02/2016
Liver Biopsy Results from Feb 2013
Portal/Periportal chronic inflammation and mild interface hepatitis (Grade 2)
Focal Lobular chronic inflammation (Grade 1)
Portal/Periportal fibrosis (stage 1-2 trichrome and reticulin stains utilized)
Negative Iron stains.
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Any Post-Treatment Reflections? 8 years 1 month ago #10537

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Well, it seems that while a lot come here and gather info, do their Tx and leave; some complete EOT but stay to offer guidance and be part of the support network. It appears that most of the soul-searching and reflection process goes on during treatment and some share this but doesn't appear to be much in the way of post-tx - if this section is any guide, which is a shame really.
Anyway, I've appreciated what has been shared.
QLD Australia ☀️
G3a HCV 35 yrs Tx naive
Started Sof/Dac 13/01/16

Dec '15
AST 70
ALT 89
GGT 124
Fibroscore 8.5
F1-F2
13 Feb'16 VL UND #woohoo!
AST 24
ALT 26
GGT 50H
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Any Post-Treatment Reflections? 8 years 1 month ago #10548

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Hi Chejai, I know what you mean about some finishing up, and moving on not to come back. For a little bit, I had that going on, thinking, well, that's that, done with that.

But, after a little while I find myself drawn back to this place, to check on those still here, to see who else is looking for answers, keeping in touch, and doing my best to inflict my bad tastes in music on the rest of the world via the Party Playlist, :evil:

What's encouraging is to see the people stepping up as some leave, others taking up the baton, to help those who come after. Not sure I'll ever totally be away from here...its too good a thing.
GT 2b; since 80's, no prior tx, sofosbuvir and daclatasvir compounded from API's at Kingswood Pharmacy in Sydney, started tx nov 6,2015, undetected at 4 wks, UND at 8 weeks, UND at 1 week after EOT, UND at 4 weeks after EOT and UND at 8 weeks after EOT. " I feel GOOD!! I knew that I WOULD!"
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Any Post-Treatment Reflections? 8 years 1 month ago #10556

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I suspect that some of the lack of comment is due to the few who have so far completed treatment mostly still awaiting their SVR results. In my imagination I can see that wait taking forever when it becomes my turn and wonder how I would comment on that at the time?

......but then again, I was always awake by 4am on Xmas day and talking to my brother about the anticipated presents, even though we weren't allowed to get out of bed and start unwrapping until six! :P
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:
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Any Post-Treatment Reflections? 8 years 1 month ago #10576

Yeah Gaj, 2B, Chejai, Lynne, and all of you here, 3 months more waiting, it's like counting every second as it goes bye. Still 10 days away from EOT myself, getting sides from the dac, Doc has suggested cutting it in half for the last 10 days or whatever is left. then the wait starts,, I've met so many amazing people in here. I used to mod on Dalnet many years ago, it was nothing like this. I've rarely met such a bunch of caring people in here, and so informative, the club just blows me away (and I've been to some weird places).
The discussions here have been robust without the put downs or any abuse from my observation. If nothing else we have been able to show a little window into this issue. Perhaps we have set an example for those in power, I don't know yet, seems like too much money is involved with disgusting examples like Gilead showing how not to help people. Too many emotions to relate, so much happening inside and nobody around me has any idea at all. Such a gift to have this forum, such a rare gift,,thank you to everyone who has been and is part of it :)
3 years cured, Sof/Dac, thanks Doc Freeman, hepc only a distant memory, go for it ppl
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Any Post-Treatment Reflections? 8 years 1 month ago #10629

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I'd guess a lot more people here are currently on Tx rather than finished. As time goes by there may be more post-tx reflections.
Also there are a lot of Looky-Loos in here but that's normal for lots of forums. Compare FixHepC forum 9 Members and 169 Guests Online, with Bleeping Computer forum 73 members, 6639 guests. :o
M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia

Any Post-Treatment Reflections? 8 years 1 month ago #10673

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2b said -
"But, after a little while I find myself drawn back to this place, to check on those still here, to see who else is looking for answers, keeping in touch, and doing my best to inflict my bad tastes in music on the rest of the world via the Party Playlist, :evil:

What's encouraging is to see the people stepping up as some leave, others taking up the baton, to help those who come after. Not sure I'll ever totally be away from here...its too good a thing."


Yeah, 2b that's true, seeing some remain and some people return to check how others are doing and keep up the support, hey even if it is to 'party'. That's one of the great things here it doesn't matter our taste in music, our pet obsessions, our anxieties and discussing all the weird shit happening in our bodies - literally :lol:

Jimmy -
"I've met so many amazing people in here. I used to mod on Dalnet many years ago, it was nothing like this. I've rarely met such a bunch of caring people in here, and so informative, the club just blows me away (and I've been to some weird places).
The discussions here have been robust without the put downs or any abuse from my observation."


Exactly Jimmy, I bet a lot of us would agree, having had experiences on other forums, FB etc. There's no 'trolling' or 'flaming' here -Thank Goodness!! Doesn't mean there aren't plenty of passionate discussions, which is great.
Says a lot about the Mods of this forum - a Big Thank You there :+1: #love

I also think that, as a group, we've experienced being social pariahs - for those who have made it known about their HCV status - and also feeling like one because of the stigma attached. We're used to carrying this 'dirty little secret' - it shouldn't be like that, we shouldn't feel 'shame' or embarrassment - but there's an isolation attached to feeling that way.

Many of us are also experiencing emotional and psychological reactions to treatment that is making us feel vulnerable, which is why those that stay here seem to have the empathy and compassion for others and that keeps the forum a safe place, a haven to come to share, vent and offer kindness and lots of 'Elove and Ehugs' to others who feel the same.

Even for those who have finished Tx and are celebrating their UND but remaining cautious as they wait for SVR's they still probably have a lot going on in their head, as Gaj commented on, and not really feel like treatment is over, done, ended or finito!
So, it's great that everyone can still check in - it's like going on a journey and returning to home base now and again :)

I'm truly grateful for all those that make this place feel so comfortable and reassuring.
I have this image in my head of Dr James having this big shed out the back of his place where anyone can stop in and stay over, have treatment or just hang out, share stories, retreat from the world and then leave when we're ready and know we can drop in anytime #love

Feel the Looooove everyone #love #love #flower
QLD Australia ☀️
G3a HCV 35 yrs Tx naive
Started Sof/Dac 13/01/16

Dec '15
AST 70
ALT 89
GGT 124
Fibroscore 8.5
F1-F2
13 Feb'16 VL UND #woohoo!
AST 24
ALT 26
GGT 50H
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Any Post-Treatment Reflections? 8 years 1 month ago #10728

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Well, I've kind of finished (in my head anyway)
In so far as I ordered 24 weeks but think I could have gotten away with 12 (sof/ dac)
So I hardly even think about it anymore (week 14 now)
I just take my pills in the morning like a vitamin and just go about things as usual

I had a bit of a low feeling around Xmas but that is not unusual as it is a 'family time'
It was the double whammy of having hep on my mind that led me to dwell on past family experiences that I feel contributed to my drug use and self loathing which led to my hep
But with a holiday i felt heaps better and back to not giving the whole hep or family thing much thought at all - a much better state of mind

I have been virus undetected since week 4 but have felt no different during the treatment at all
I can honestly say I feel no better or no worse than before i started - I was even worried they were placebos initially lol except for the taste
I originally was taking them at night as I thought they could make me nauseous
As they didn't i changed to mornings so I could drink more water after taking them (a bit dehydrating)

I guess my biggest reflection has been the belief that the hep has overall been a positive in my life
It has forced me to concentrate a lot on my health and wellbeing
i have never actively thought about the complications, only about what i can do to lead a normal healthy life
The only time I have actively thought about a hep death is during tx when i researched how to get my hands on Nembutal in case I do ever need to die on my terms rather than some medical practitioners

I've seen a few people die, and some quite young, some quite unexpected
Go into any high care facility and look at all the living corpses that aren't allowed to die - it's a fate worse than death
Death can happen anytime and anywhere so I'm not going to give it any more thought than 'what will be will be or pass me the Nembutal'

And lastly...when I first read about the buyers club and Dr Freeman it all sounded too good to be true - I am extremely cynical about such things
I swore that after the last tx debacle i would never do tx again unless i could be guaranteed the sides were insignificant enough to warrant it
I went straight to this website and checked it out - it seemed legit with lots of people undertaking tx with little or no sides

Not having given any thought to my hep for 12 years i had no info or blood tests and didn't know where to start
I finally spoke to the doc who said, doesn't matter G1 or G3,, liver damage, or VL - start immediately and get yourself cured - here's a script and what to do to get it filled
i had not previously, and probably will never again hear such practical advice from someone with Dr in front of their name
How lucky am I/ we that we have the monetary and practical means to cure ourselves on our terms - it's incredible really

Anyhoo, as I've been scorned for before, I do like a drink and it's fast approaching beer o clock
So if you excuse me i'm going to smoke a reefer to get the thirst going :P

Love to all :kiss:
Sure are some great people on this site and behind the scenes so thanks for everything!
52 y.o. G3a for about 30 years
Previous tx 2004 interferon/ ribavarin
2004: ALT 624 AST 263

Pre tx test 23/10/15: ALT 153 AST 128 VL 11 849 493
6/11/15: Sof/ dac started
26/11/15: ALT 41 AST 41
7/12/15: ALT 36 AST 30 Virus undetected

2004 biopsy F3
Fibroscan appt Jan 11 2016.
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