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2B HERE 8 years 1 month ago #11282

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I wondered about that, now that I'm more aware of treatment options. When I started, I was offered only the regimen I'm on. It may be too late now, I have only 3 more weeks of treatment. I wish I had known then what I know now.
LLJ

Geno 2b; Fibrosure 4. Tx: sovosbuvir/ribavirin x 16 weeks. EOT March 4, 2016
0 weeks: RNA = 10012000 iu/ml; log10 = 7.001. AST 129; ALT 133
4 weeks: PCR Quantitation = 60 iu/ml; log10 = 1.778. 5 weeks: PCR Quantitation < 15 (UND); AST 35; ALT 24

2B HERE 8 years 1 month ago #11289

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hey hey hey...i am the ORIGINAL "2B" here.... :)
for what its worth, i took no ribavirin, i had it since 80's, and sofosbuvir and daclatasvir has seemed to have done the job.
got my test results from 1 week past the 12 weeks eot, and was UND and was UND at 4 and 8 weeks too.

best of luck to all 2B's and or course all the other b's and a's and c's and rest of the alphabet...

yes we are exotic, 2b or not 2b..but .i think now im no longer 2b,,,..im just me
GT 2b; since 80's, no prior tx, sofosbuvir and daclatasvir compounded from API's at Kingswood Pharmacy in Sydney, started tx nov 6,2015, undetected at 4 wks, UND at 8 weeks, UND at 1 week after EOT, UND at 4 weeks after EOT and UND at 8 weeks after EOT. " I feel GOOD!! I knew that I WOULD!"
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2B HERE 8 years 1 month ago #11302

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2b, that's brilliant. Congratulations. It seems so far away to me.
LLJ

Geno 2b; Fibrosure 4. Tx: sovosbuvir/ribavirin x 16 weeks. EOT March 4, 2016
0 weeks: RNA = 10012000 iu/ml; log10 = 7.001. AST 129; ALT 133
4 weeks: PCR Quantitation = 60 iu/ml; log10 = 1.778. 5 weeks: PCR Quantitation < 15 (UND); AST 35; ALT 24

2B HERE 8 years 1 month ago #11309

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Hi LLJ, Same here as 2b, I took no riba, am on sof/dac just finishing up my 5th week and was UND at 4wks.
Have you done any labs while on tx? You can post them in your signature in your profile.
Best wishes to SVR and hope you are not having too many sides from the riba.
GT2b diagnosed 10/2015
since: unknown
11/20/15 VL= 214,070
12/4/15 ALT=18 AST= 24
1/16/16 started sof/dac
2/13/16 @4wks VL=UND ALT=13 AST=22
3/12/16 @8wks VL=UND ALT=10 AST=18
4/9/16 EOT VL=UND ALT=11 AST=19
9/23/16 SVR24 ALT=11 AST=22

2B HERE 8 years 1 month ago #11327

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Hi LLJ,
I am also 2B and also no longer 2b :) I am on week 15/24 of Sof/Dac and was UND at 4wks. I have cirrhosis according to my Specialist although I have never had Fibroscan, hence the 24 weeks treatment.
Best of luck with your treatment :) Have you had any tests to see if you have cleared since you only have 3 weeks to go? I Hope all is going well :+1:
G2B - DIAGNOSED 2014, STARTED SOF/DAC 11/11/15 VL 6M
UND @ WEEK4
FINISHED TREATMENT 26/4/16
UND @ WEEK 24
ALT 12 AST 15
MY ETERNAL GRATITUDE TO GREG JEFFERYS & DR FREEMAN

2B HERE 8 years 1 month ago #11328

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Hi, I'm so glad to see you are doing well. I had labs before starting treatment, then viral load and LFT's in 4 weeks. He did another viral load a week later because it had decreased but was not UND; it went to <15 (UND) the second time.

I'm supposed to have labs again after end of treatment (2 weeks from now, I miscalculated), and again in 12 weeks.

I wish I had known about this site before I started. It was considered unusual for insurance to approve as much as 16 weeks, I would have done more meds if I'd had the chance. I can even put up with the Ribavirin.

The lab values are under my signature, if I did it right.
LLJ

Geno 2b; Fibrosure 4. Tx: sovosbuvir/ribavirin x 16 weeks. EOT March 4, 2016
0 weeks: RNA = 10012000 iu/ml; log10 = 7.001. AST 129; ALT 133
4 weeks: PCR Quantitation = 60 iu/ml; log10 = 1.778. 5 weeks: PCR Quantitation < 15 (UND); AST 35; ALT 24
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2B HERE 8 years 1 month ago #11329

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With two weeks to go it would be easy to get 4-8 weeks generic Sof+Dac to finish off with, the goal being kill off any remaining resistant mutants.

Chances are you will SVR but retreatment with 24 weeks Sof+Dac should work well with no prior NS5A exposure and is far less than most co-pays.
YMMV
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2B HERE 8 years 1 month ago #11334

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I have fingers & toes crossed for a good result for you :)
And as Dr Freeman says, you have options here if you want to make sure. :+1:
G2B - DIAGNOSED 2014, STARTED SOF/DAC 11/11/15 VL 6M
UND @ WEEK4
FINISHED TREATMENT 26/4/16
UND @ WEEK 24
ALT 12 AST 15
MY ETERNAL GRATITUDE TO GREG JEFFERYS & DR FREEMAN

2B HERE 8 years 1 month ago #11465

i have .sof/dac 8weeks test clear not detected.
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2B HERE 8 years 1 month ago #11486

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Hi Viki, congratulations on your 8 week result and welcome to the site! :+1: :)
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:
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2B HERE 8 years 1 month ago #11532

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Congratulations Viki #woohoo!
G2B - DIAGNOSED 2014, STARTED SOF/DAC 11/11/15 VL 6M
UND @ WEEK4
FINISHED TREATMENT 26/4/16
UND @ WEEK 24
ALT 12 AST 15
MY ETERNAL GRATITUDE TO GREG JEFFERYS & DR FREEMAN

2B HERE 7 years 11 months ago #15124

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Day 168 is here finally!!! Last pills down the hatch!! Sof/Dac 24 wks Geno 2B 35yrs.
Thank you James Freeman and Greg Jefferys #love #love #love
I finally get my fibroscan on the 17th May, hopefully finally find out my cirrhosis status.
Thank you everyone for posting and allowing me hang around and keep myself sane :)
#woohoo!
G2B - DIAGNOSED 2014, STARTED SOF/DAC 11/11/15 VL 6M
UND @ WEEK4
FINISHED TREATMENT 26/4/16
UND @ WEEK 24
ALT 12 AST 15
MY ETERNAL GRATITUDE TO GREG JEFFERYS & DR FREEMAN
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2B HERE 7 years 11 months ago #15128

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Congratulations IRMA88! :woohoo:

Sounds like there are a few of us 24 weekers finishing Tx around now. Mine is next week so we'll be able to compare SVRs. :)
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:
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2B HERE 7 years 11 months ago #15131

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Hi Irma88 and Gaj,

I am also finishing my 24 weeks with my last pills this Thursday. That makes 12 weeks of Sof/Led and 12 weeks of Sof/Dac.
It will be strange but good not to have that nightly ritual. Good luck to all for the next stage :+1:

Coral
G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!)
Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back!
New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217.
SVR12 and SVR 24
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2B HERE 7 years 11 months ago #15132

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Hi all EOTers
Welcome Viki and CONGRATS :+1: :+1:
IRMA, GAJ and Coral good luck from me wishing you the best.
Many more of us are now at the testing part EOT and beyond its kept me sane the support from some fantastic members here too IRMA.
My bloods get done Friday for the SVR4 and I am nervous as all hell too.
We're all in this together that is the comforting thing

And big congrats to 2b from me :)
So onwards to EOT team and good luck to all I will be counting down with you in spirit
Love from Ariel #flower #flower #flower
Gen 1a
Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas.
pre sof/led VL 240,000 Fibsc F0
Day 25 <30
Day 32 UND
Week 10 UND
EOT UND ALT11AST17GGT19
SVR4 UND ALT10 AST16 GGT13
SVR8 UND ALT <9 AST16 GGT15
SVR12 UND ALT14 AST19 GGT12 Bili 5
EOT +18 ALT13 AST20 GGT9 Bili 5
EOT +21 ALT11AST15
Cured SVR12
Dysplasia Adenomas RemvdAug '16
SVR24 UND ALT11AST16
ColonoscopyClear Nov17
LumpectomyClear ‘18
LithotripsyCytoscopyBiopsy 4/18
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