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TOPIC: undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr

undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 6 months ago #14859

  • Bob in ireland
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Just got a bit of positive news-- undetectable - although they are concerned about shady area showing up on ultrasound scan--had an ultrasound scan 6 months prior wasnt there then-- was told could be a bad scan by inexpereinced tecchy or bad interpretation or worse cas scenario a nodule/or cancer...yikes-- no cancer indicators in my latest bloods-- so they are sceduling an MRI scan to get a better look

still am glad I ve hit the undetectable point lets pray and hope for an SVR

best from

Rob ireland

ps James --did you meet Orla C from Ireland :+1: over in barcelona?
Last Edit: 5 years 6 months ago by Bob in ireland.
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 6 months ago #14874

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This is fantastic news!! Keep taking the meds bro!

It beats them damn squirrel feces salads :cheer: :+1:

Good for you!!

SVR 24 here you come dude!!
Gt 1a, F0, VL 6.5 million, AST 59, ALT 62
Started Twinvir 1/15/16
6 wk. labs VL UND, AST 27, ALT 20
EOT labs VL UND, AST 23, ALT 19
SVR 16, VL UND, AST 28, ALT 17
SVR 24 , VL UND, 10/8/16
SVR 125, VL UND, 9/22/18
SVR 230, VL UND, 10/3/20
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 6 months ago #14891

  • LondonGirl
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Pleased to read you're UND week 9 :+1: and good luck with the more detailed scan. I'm suprised they can see anything much at all if Ireland have similar USound scan equip to the ones we have locally to me here in England!
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 'In the slow lane'
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
Last Edit: 5 years 3 months ago by LondonGirl.
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 6 months ago #15015

  • Ariel
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Congratulations Bob
Hoping the liver is okay
Focusing on the UND is the go I wish you all the very best onwards from here
Ariel #flower #flower #flower
Gen 1a
Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas.
pre sof/led VL 240,000 Fibsc F0
Day 25 <30
Day 32 UND
Week 10 UND
EOT UND ALT11AST17GGT19
SVR4 UND ALT10 AST16 GGT13
SVR8 UND ALT <9 AST16 GGT15
SVR12 UND ALT14 AST19 GGT12 Bili 5
EOT +18 ALT13 AST20 GGT9 Bili 5
EOT +21 ALT11AST15
Cured SVR12
Dysplasia Adenomas RemvdAug '16
SVR24 UND ALT11AST16
ColonoscopyClear Nov17
LumpectomyClear ‘18
LithotripsyCytoscopyBiopsy 4/18
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 6 months ago #15016

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Congratulations, it's a good sign! :cheer:

Hope the MRI goes well for you, keep us posted.

x
J the young dragon slayer is:
HepC 1a since birth
Male aged 15
VL 2000000
Started Twinvir/ 10-11-15-then Sof/led.
NO sides so far !
after one week VL : 37
after 4 wks VL : UND !
EOT 2/2/16 UND.!
4 wks. post tx results....pending....
7/3/16 VL result : 4 week post tx: SVR !
12 weeks SVR !
24 wks SVR yeeaa!!
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 6 months ago #15071

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:cheer: Thanks everyone for the kind messages - wishing you all well
love from The Emerald isle :) :+1: #love
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 6 months ago #15072

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Hi LG-- I reckon the machines are the same over here-- i did feel the operator wasnt really with what she was doing!!! -so many variables--
fingers crossed -no cancer markers in blood test results ;)
hope all well over in Blighty ;) #flower
Last Edit: 5 years 6 months ago by Bob in ireland.
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 6 months ago #15088

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Great news Bob from Ireland!! WTG!!


G1a dx'd in 1992, Biopsy F2 VL 8mill +. Tried tx with Interferon/Riba, back in 2008 didn't last long it felt horribly ugly!! I stopped tx, after 5 weeks!!
Started tx 6/1/16 with Harvoni.
12 Month Labs= UND
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 5 months ago #16117

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Hi Bob,

Did you buy your meds online? Just wondering about hassle getting them into the country, I've trawled the threads for anyone with experience getting them into Ireland. Any advice or knowledge gleaned from your experience would be hugely appreciated, thanks.

Mike (also in Ireland)
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 5 months ago #16186

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Hi Mike, didnt have to go that route as I am F3 and have varices -which was the main criteria for getting the meds thru the HSE -

I am pretty sure getting the generics wont be a problem -- i am sure there some folk here who have done it in ireland-- if not you could always fly out and bring back the meds with you ?
good luck
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 5 months ago #16187

  • Bob in ireland
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I had MRI scan of liver - no carcinoma/nodules etc. did pick up the 4 varices - consultant wants me to up the dose of beta blockers to reduce pressure on portal hypotension-- so i was told i have precompensated liver disease with portal hypotension.
still undetectable at halfway point-- whether to take riba for last month as addition is on my mind any ideas?
pllatelets gone up from 42,000 to 59,000 in last month and white blood cell count is up as well - alts 67 .
dont feel too bad - bit of tiredness and headaches occasionally.
from Bob
:+1: :cheer:
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 5 months ago #16190

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:+1:
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 5 months ago #16194

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Cirrhotics respond slower.

The rise in platelets is encouraging, suggesting your portal pressures have fallen and you spleen shrunk a bit.

With portal hypertension using beta blockers looks to me to be a historical hangover. They were one of the first effective antihypertensive medications but the sides include tiredness and sexual dysfunction issues.

ACE inhibitors also work and this has been known since 1992!

www.ncbi.nlm.nih.gov/pubmed/1586932

And rediscovered in 2013!

www.ncbi.nlm.nih.gov/pmc/articles/PMC3627462/

Here is some detailed commentary on it:

f1000.com/prime/reports/m/6/95/

The driving issue for you is HCV. Fixing that will go a long way towards fixing the problem and preventing progression.
YMMV
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 5 months ago #16209

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Hi James , thanks so much for some clarity on the betablocker issue--i was taking only 20mg at night-- but am very sensitive to anything like that- I was wondering where my libido had gone,was feeling lethargic in the mornings- I phoned my consultant and asked whether she would prescribe an ACE inhibitor as a substitute to the beta blockers-- didnt get a positive response wouldnt do it -and my local gp is scared about treading on my consultants toes.. so I might drop the betas altogether -most nights ive only been taking 10mg (reluctance to take them )

I noticed that there are quite a few foods that contain ACE inhiibiting componenets such as :
Casokinins and lactokinins, breakdown products of casein and whey, occur naturally after ingestion of milk products, especially cultured milk. .
The lactotripeptides Val-Pro-Pro and Ile-Pro-Pro produced by the probiotic Lactobacillus helveticus or derived from casein have been shown to have ACE-inhibiting and antihypertensive functions.

I did restart taking a good brand of probiotics with Lactobacillus helveticus in it- also I ve been starting to make homemade KEFIR

this is an excellent link for info on ACE inhibiting foods materials
onlinelibrary.wiley.com/doi/10.1111/1541-4337.12051/full

will boost up on some specific foods :) I ve cut out carbs almost completely - high protein grassfed lamb/beef etc loads of green veggie etc. cutting out stuff with sugar in has been quite a challenge-- !!

Thanks James
will let you know how things unfold
Blessings from the Emerald Isle

Bob :) #flower
Last Edit: 5 years 5 months ago by Bob in ireland. Reason: speelin errors!
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undetectable at 9 weeks sof/dac gen 3a F3 inf/rib relapsr 5 years 5 months ago #16215

  • Matt-Kenney-google
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Hey Bob in Ireland, keep on the path man! It's great to see you're "demon" getting under control.

... thanks for the supplements advice too. Good stuff to know.
GT1a; Got it some time in the 70's; Diagnosed @1976
Tx naive
METAVIR: A2-F2
SOT May 18, 2016: CMP: AST 162 ALT 241 VL 13000000
3 weeks after SOT: AST 27 ALT 31 VL 138
Reached EOT Aug. 10, 2016 / Received svr4 results Sept. 20, 2016: AST 22 ALT 24
Hep C RNA "NOT DETECTED"
AS OF 3/20/2017 ,Hep C RNA PCR "NOT DETECTED" THAT'S SVR24!
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