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Young J the dragon slayer 6 years 10 months ago #3739

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This is really great news for J, and you too of course, Cindi. That is a fantastic drop in VL! So, glad he's feeling happier. I was 18 when I got it and have had depression most of my life, genetic predisposition but living with this chronic virus may well have factored in.
It's awesome you have taken this step for your son :)
QLD Australia ☀️
G3a HCV 35 yrs Tx naive
Started Sof/Dac 13/01/16

Dec '15
AST 70
ALT 89
GGT 124
Fibroscore 8.5
F1-F2
13 Feb'16 VL UND #woohoo!
AST 24
ALT 26
GGT 50H

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Young J the dragon slayer 6 years 10 months ago #4291

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Hi,
I've been looking on the drug interaction chart but can't find " Brompheniramine" I think it's an antihistamine. It's in a med called Dimetapp, which J needs at night when he has a cold, and he seems to be getting one.

I see the other ingredient "Phenylephrint" is ok with the Harvoni.

Can anyone help with this?
Anyone know?

J will have done 4 weeks tomorrow & will get his bloods done.
he's going well other than getting a sore throat now.
I really grilled him the other day about sides, as he doesn't say much.

It appears the only difference he's really felt on these orals is his appetite is a bit less.
Not as hungry, & eating less.
That's all. :)

Hope someone can come back with any advise about the drug interaction.

All the best to everyone,

Cindi x
J the young dragon slayer is:
HepC 1a since birth
Male aged 15
VL 2000000
Started Twinvir/ 10-11-15-then Sof/led.
NO sides so far !
after one week VL : 37
after 4 wks VL : UND !
EOT 2/2/16 UND.!
4 wks. post tx results....pending....
7/3/16 VL result : 4 week post tx: SVR !
12 weeks SVR !
24 wks SVR yeeaa!!

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Young J the dragon slayer 6 years 10 months ago #4293

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Also what about vit. C or Sambucol which seems to just be "Sambucas nigra" ( black elderberry)
Can't find anything like this on drug interaction chart.

The problem with J is he's a fussy eater, doesn't eat fruit & hates vegies except shelled peas.Maybe I can bribe a carrot into him & potatoes.
That's about it.
Once we offered him $20 just to "try" a banana, but he refused :ohmy: ....we did start off a lot lower but it got up to that amount & we gave up.

Very difficult to get vitamins into him except for the pill kind, and since starting the Led/sof, he's had NO sups at all.

Any suggestions?
x
J the young dragon slayer is:
HepC 1a since birth
Male aged 15
VL 2000000
Started Twinvir/ 10-11-15-then Sof/led.
NO sides so far !
after one week VL : 37
after 4 wks VL : UND !
EOT 2/2/16 UND.!
4 wks. post tx results....pending....
7/3/16 VL result : 4 week post tx: SVR !
12 weeks SVR !
24 wks SVR yeeaa!!

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Young J the dragon slayer 6 years 10 months ago #4295

According to pubchem.ncbi.nlm.nih.gov/compound/brompheniramine

The metabolic pathway has not been full characterised.

So while it should be fine, as short a period of use as possible would be best.
YMMV
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Young J the dragon slayer 6 years 10 months ago #4296

I can't find anything at all on the Dimatap but I think the Vitamin C is fine as I have seen it recommended for use on treatment elsewhere. Fussy eater eh ? I suppose mung beans, brussel sprouts and spinach are all out as well :)
Two time relapser.

SVR 4 achieved 12/16 at last
SVR 12 achieved 22/02/2017 The Bastard has been defeated :):):)

GT 3 - about 28 yrs with HCV
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Young J the dragon slayer 6 years 10 months ago #4298

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Thanks Dr James, I'll wait 'till when & if it get bad enough to use that.
J the young dragon slayer is:
HepC 1a since birth
Male aged 15
VL 2000000
Started Twinvir/ 10-11-15-then Sof/led.
NO sides so far !
after one week VL : 37
after 4 wks VL : UND !
EOT 2/2/16 UND.!
4 wks. post tx results....pending....
7/3/16 VL result : 4 week post tx: SVR !
12 weeks SVR !
24 wks SVR yeeaa!!

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Young J the dragon slayer 6 years 10 months ago #4299

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Thanks Paul, yes I'll give him Vit C later tonight.

I suppose mung beans, brussel sprouts and spinach are all out as well

Hehe! definitely none of those foods!!!! :lol:
You know how weird it is, he won't eat mango's ( even a slither) or watermelon, or any of those nice summer fruits, he loves strawberry milkshakes & ice-cream but wont touch a strawberry.

Oh.... just remembered, he has eaten little bits of pealed apple before if the bribe's good enough.

....but that's about it.
J the young dragon slayer is:
HepC 1a since birth
Male aged 15
VL 2000000
Started Twinvir/ 10-11-15-then Sof/led.
NO sides so far !
after one week VL : 37
after 4 wks VL : UND !
EOT 2/2/16 UND.!
4 wks. post tx results....pending....
7/3/16 VL result : 4 week post tx: SVR !
12 weeks SVR !
24 wks SVR yeeaa!!
The following user(s) said Thank You: Paul-Jarman-facebook

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Young J the dragon slayer 6 years 10 months ago #4300

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Hmmm. Shepherds pie, lasagna, spaghetti bol, meatloaf, hamburgers, homemade sausage rolls?

Pretty much anything using (not too lean) mince meat you can grate up some carrot, zucchini, onion, etc. the thicker and richer flavoured any sauce is, and the finer you grate the more you can get away with but don't use too much in the beginning.

Blitz fresh strawberries with some strawberry syrup?

G
<who assisted R&D of many 'healthy' hiding skills> B)
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:

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Last edit: by Gaj.

Young J the dragon slayer 6 years 10 months ago #4301

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I couldn't find anything specifically on that one either, Cindi


But here is a complete rundown of all 156 drugs which interact with Harvoni: Hope you find something there, couldn't see Brompheniramine.


www.drugs.com/drug-interactions/ledipasv...osbuvir,harvoni.html
GT1a since 1988, diagnosed 1990
F0, tx naive
VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 - 2.9
Started Mesochem sof/dac 12 weeks 01/01/2016
11/02/2016 - 6 weeks UNDETECTED
AST 26
ALT 26

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Young J the dragon slayer 6 years 10 months ago #4302

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CJ wrote: Thanks Paul, yes I'll give him Vit C later tonight.

I suppose mung beans, brussel sprouts and spinach are all out as well

Hehe! definitely none of those foods!!!! :lol:
You know how weird it is, he won't eat mango's ( even a slither) or watermelon, or any of those nice summer fruits, he loves strawberry milkshakes & ice-cream but wont touch a strawberry.

Oh.... just remembered, he has eaten little bits of pealed apple before if the bribe's good enough.

....but that's about it.



Kids, huh! :)

I guess gone are the days when you were told to eat what was put in front of you, or you wouldn't get anything else...yeah my parents were very old-school. Consequently I have a deep and abiding intolerance of brussel sprouts, parsnips & turnips :lol:
GT1a since 1988, diagnosed 1990
F0, tx naive
VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 - 2.9
Started Mesochem sof/dac 12 weeks 01/01/2016
11/02/2016 - 6 weeks UNDETECTED
AST 26
ALT 26

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Last edit: by zhuk.

Young J the dragon slayer 6 years 10 months ago #4303

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Hi zhuk,

Yeah, mine were old school too, but we had quite a fat, greedy sausage dog, when we were young, & we could sneak our brussel sprouts etc. under the table to him :P
J the young dragon slayer is:
HepC 1a since birth
Male aged 15
VL 2000000
Started Twinvir/ 10-11-15-then Sof/led.
NO sides so far !
after one week VL : 37
after 4 wks VL : UND !
EOT 2/2/16 UND.!
4 wks. post tx results....pending....
7/3/16 VL result : 4 week post tx: SVR !
12 weeks SVR !
24 wks SVR yeeaa!!

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Young J the dragon slayer 6 years 10 months ago #4305

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Haha CJ, win!

I am an only child though, so it was harder to get away with things in general :P
GT1a since 1988, diagnosed 1990
F0, tx naive
VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 - 2.9
Started Mesochem sof/dac 12 weeks 01/01/2016
11/02/2016 - 6 weeks UNDETECTED
AST 26
ALT 26

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Last edit: by zhuk.

Young J the dragon slayer 6 years 10 months ago #4307

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Oh yeah it would have been harder, we were forever grateful for our little doggy garbage bin!

But you were probably healthier for it zhuk, :)
x
J the young dragon slayer is:
HepC 1a since birth
Male aged 15
VL 2000000
Started Twinvir/ 10-11-15-then Sof/led.
NO sides so far !
after one week VL : 37
after 4 wks VL : UND !
EOT 2/2/16 UND.!
4 wks. post tx results....pending....
7/3/16 VL result : 4 week post tx: SVR !
12 weeks SVR !
24 wks SVR yeeaa!!

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Young J the dragon slayer 6 years 10 months ago #4313

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Hmmm, maybe so heh

My mum grew up in the Depression so they was the inevitable "clean your plate because there are starving children in India" directive too :lol:
GT1a since 1988, diagnosed 1990
F0, tx naive
VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 - 2.9
Started Mesochem sof/dac 12 weeks 01/01/2016
11/02/2016 - 6 weeks UNDETECTED
AST 26
ALT 26

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Young J the dragon slayer 6 years 10 months ago #4315

When I grew up we were told to think of all the starving Biafrans, they were welcome to my sprouts but never got them.
Two time relapser.

SVR 4 achieved 12/16 at last
SVR 12 achieved 22/02/2017 The Bastard has been defeated :):):)

GT 3 - about 28 yrs with HCV

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