emo isaing4 Twinvir story

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6 years 6 months ago #5908

4/52 possiblity means ,every 4 weeks for 52 weeks.


Gen 1b, F1-F2. Naive.
Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
Starting VL 400000, Alt 49/AST 44
1 week VL 29, ALT 44/AST 30.
4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
7 weeks VL Detected, ALT 28, all other normal
8 weeks UND, 12 week UND, 24 week SVR UND
Last Edit: 6 years 6 months ago by Dan.
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6 years 6 months ago #5911

Thank you, Dan!
Urea and Creatinine - done and are OK
The electrolytes, the various salts in the bloodstream... things like sodium, potassium, chloride and bicarbonate.- never done, as I remember. :(
But I shall test at 4 weeks! B)
And 52 weeks? Why? As I understand the treatment is either 12 weeks or 24 weeks.
I don't understand. :unsure:


HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive,
started 12 wks Twinvir on 06.12.2015. Feeling great and grateful :)
virus not detected 06.02.2016 & SVR24
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6 years 6 months ago #5912

Not sure, but you need to check post treatment your VL at 4, 12 and 24 weeks, to see if you reached SVR.

Check this thread
fixhepc.com/forum/questions-and-answers/...apse-whats-next.html


Gen 1b, F1-F2. Naive.
Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
Starting VL 400000, Alt 49/AST 44
1 week VL 29, ALT 44/AST 30.
4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
7 weeks VL Detected, ALT 28, all other normal
8 weeks UND, 12 week UND, 24 week SVR UND
Last Edit: 6 years 6 months ago by Dan.
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6 years 6 months ago #5913

The quote mentioned earlier is from
fixhepc.com/forum/forum-gp-cheat-sheet.html
Monitoring paragraph.

Treatment success SVR 4/ SVR12/ SVR 24 with SVR24 weeks - the final goal, cured 99%. For me - september 2016! :cheer:
Thank you Dan!


HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive,
started 12 wks Twinvir on 06.12.2015. Feeling great and grateful :)
virus not detected 06.02.2016 & SVR24
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6 years 6 months ago #5914

I have one more question.
ALT/AST ratio does have a meaning during treatment?
Does anyone know?
:unsure:


HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive,
started 12 wks Twinvir on 06.12.2015. Feeling great and grateful :)
virus not detected 06.02.2016 & SVR24
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6 years 6 months ago #6047

A belated welcome here isaing4! Great you are doing well already.

My understanding of the 4/52 is it's an abbreviation - a way of indicating @ 4 weeks, as there are 52 weeks in a year; therefore testing @ 8 weeks would be written 8/52. It doesn't mean it's the length of your treatment.

All the best for the rest of your Tx :)


QLD Australia ☀️
G3a HCV 35 yrs Tx naive
Started Sof/Dac 13/01/16

Dec '15
AST 70
ALT 89
GGT 124
Fibroscore 8.5
F1-F2
13 Feb'16 VL UND #woohoo!
AST 24
ALT 26
GGT 50H
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6 years 6 months ago #6191

HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive,
started 12 wks Twinvir on 06.12.2015. Feeling great and grateful :)
virus not detected 06.02.2016 & SVR24
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6 years 6 months ago #6197

Just to confirm what others have already correctly told you.

4/52 is doctor code for 4 weeks

8/52 would be 8 weeks


YMMV
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6 years 5 months ago #6492

I just received 2 weeks viral load, down to 514 from 9 mil. Yay! :woohoo:
I know, there are targets to be achieved, the first UND and SVR24. But right now I am confident that cure is possible for me.
Happy New Year and be all cured in 2016! :lol:


HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive,
started 12 wks Twinvir on 06.12.2015. Feeling great and grateful :)
virus not detected 06.02.2016 & SVR24
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Last Edit: 6 years 5 months ago by isaing4.
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6 years 5 months ago #6493

I have a question, please! :unsure:
On my blood test paper is written:
method of work limit of detection in the field of linearity ( measurable ) 45 UI/ml
analytical sensitivity 15 UI/ml

Why the measurable limit of detection is not equal with the sensitivity? When UND the viral load is < then 15 UI/ml or <45 UI/ml?
Thanks!
I just want to know how good is my lab. :cheer:


HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive,
started 12 wks Twinvir on 06.12.2015. Feeling great and grateful :)
virus not detected 06.02.2016 & SVR24
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6 years 5 months ago #6495

It can measure accurately from 45 to 100 000 000. Under 45 it can only detect between 15 and 45 but not quantifiable. Below 15 the apparatus can not detect it. So <15, it means UND for the Lab.

Your Lab is very good.


Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured
Last Edit: 6 years 5 months ago by Enkel.
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6 years 5 months ago #7484

Hi Isaing4,

How you doing, any news?


Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured
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6 years 5 months ago #7644

Thanks I am fine. :cheer:
Still waiting 4 weeks viral load. :huh:
I also tested vit B12 and vit D and waiting the result . I am considering to take those vitamins if there is a deficiency.
All the best! To each and every one of you! #duck #duck #duck #duck #duck #duck #duck #duck #duck #duck #duck #duck


HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive,
started 12 wks Twinvir on 06.12.2015. Feeling great and grateful :)
virus not detected 06.02.2016 & SVR24
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6 years 5 months ago #8388

Still waiting 4 weeks viral load. The lab told me the result will come monday! :ohmy:
But I have vitamin D and B12 results. The levels are in normal range but low.
So I will take vit D and B12. :cheer:


HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive,
started 12 wks Twinvir on 06.12.2015. Feeling great and grateful :)
virus not detected 06.02.2016 & SVR24
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Last Edit: 6 years 5 months ago by isaing4.
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6 years 5 months ago #8640

Just got my viral load result, 83. :woohoo:
I am a slow responder like F4, even my fibroscan/fibromax is good with F0/F1.
I am taking B12 and D vitamin from today. Hoping all the best for me and all of you! :lol:


HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive,
started 12 wks Twinvir on 06.12.2015. Feeling great and grateful :)
virus not detected 06.02.2016 & SVR24
This email address is being protected from spambots. You need JavaScript enabled to view it.
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