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isaing4 Twinvir story 8 years 7 months ago #8641
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If my viral load is not UND at 6 weeks, half treatment...
Maybe it is recommended to prolonged the treatment with 4 weeks, with a total of 16 weeks? I don't know, I am a little bit disappointed.  Any advice will be appreciated. Thanks!  HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive, started 12 wks Twinvir on 06.12.2015. Feeling great and grateful virus not detected 06.02.2016 & SVR24 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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isaing4 Twinvir story 8 years 7 months ago #8642
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I know from
fixhepc.com/forum/viral-load-and-svr/287...ct.html?limitstart=0 that after 8 weeks I have a big chance of UND. But if not, maybe I must continue the treatment more then 12 weeks. So I have to arrange to buy the medication as soon as possible. Dr. James please consider my question if you have some little time.  Thank you so much! HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive, started 12 wks Twinvir on 06.12.2015. Feeling great and grateful virus not detected 06.02.2016 & SVR24 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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isaing4 Twinvir story 8 years 7 months ago #8650
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Hi Enkel,
Thanks! Good idea to test at another lab!  But at this one I have 50% discount. Maybe I will try another lab at 8 weeks!  HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive, started 12 wks Twinvir on 06.12.2015. Feeling great and grateful virus not detected 06.02.2016 & SVR24 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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isaing4 Twinvir story 8 years 7 months ago #8653
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Hi isaing4 Thankyou for your really great data in your blog and your questions they are very helpful to many people incl myself here on only Day 8. I know of a few people who have done all extra six weeks
I also hear that some are still detected at 4 weeks but clear later on It seems that the aim of achieving an SVR isn't tightly linked to the four weeks result to my thinking Wishing us all our SVR hang in there all Cheers from Ariel PS sorry for the late reading of your story I am relatively new to the forum  Gen 1a
Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas. pre sof/led VL 240,000 Fibsc F0 Day 25 <30 Day 32 UND Week 10 UND EOT UND ALT11AST17GGT19 SVR4 UND ALT10 AST16 GGT13 SVR8 UND ALT <9 AST16 GGT15 SVR12 UND ALT14 AST19 GGT12 Bili 5 EOT +18 ALT13 AST20 GGT9 Bili 5 EOT +21 ALT11AST15 Cured SVR12 Dysplasia Adenomas RemvdAug '16 SVR24 UND ALT11AST16 ColonoscopyClear Nov17 LumpectomyClear ‘18 LithotripsyCytoscopyBiopsy 4/18 |
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isaing4 Twinvir story 8 years 7 months ago #8665
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Hi Isaing - Do I read correctly that your VL came down from 9 million?
(Can't see your Profile while typing this on small device, so much more tricky keeping up since big comp. out of action) If so, that may explain your result somewhat? it would have come down quite alot! Agree with Ariel over this, I've even read some people have been detected at EOT only to clear and know of someone personally who was 15 at EOT and went on to clear, so it could well be worth checking at another lab in 2 weeks. Agree also, be prepared,just in case, but that's a magnificent drop really, 9 mil to 83 . Wishing you all the very best for success and get those Bs & Ds down you  GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption Baseline: VL 913575 Alt 76 Platelets low Wk2 VL1157 Alt 23 DET Wk 8 VL 32 Alt19 'In the slow lane' June16 Fibro 5.7 F0/1 LIF 1.5 Wk 11 VL<12 Alt 13 Det/Unq Extending tx 12 wks Mylan Sofo/Dac MonkMed Wk 14 VL <12 Det/Unq Wk 16 VL UNDETECTED Wk 22 + 4 Wks Sunprevir FixHepC Wk 24 UNDETECTED Alt 13 Wk 12 post tx SVR12 Wk 26 SVR24 Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC |
isaing4 Twinvir story 8 years 7 months ago #8722
Good luck and........UND HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive, started 12 wks Twinvir on 06.12.2015. Feeling great and grateful virus not detected 06.02.2016 & SVR24 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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isaing4 Twinvir story 8 years 7 months ago #8725
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Thanks Ariel the mermaid, like your name
Thanks LondonGirl, good choice also for your name, remind me of being spontaneous and young It is a big drop from 9.000.000 to 83 in 4 weeks. Those bastards were so many and they were feeling so good inside my liver/body. I was a polite host, but not anymore!  Generally, I think positive and I am an optimistic. Happy with my progress toward regaining my health!  All the best and UND soon to everyone of you!  HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive, started 12 wks Twinvir on 06.12.2015. Feeling great and grateful virus not detected 06.02.2016 & SVR24 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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isaing4 Twinvir story 8 years 7 months ago #8731
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Heh you are right, isaing! The bastards were indeed many - and most have been decimated now, only the more persistent stragglers left
As LG says, you can have detectable levels at EOT and still go on to achieve SVR, so I wouldn't be worrying at 4 weeks. Easy to say I know, when you read of others getting UND by that time. But there's still a long way to go GT1a since 1988, diagnosed 1990
F0, tx naive VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 - 2.9 Started Mesochem sof/dac 12 weeks 01/01/2016 11/02/2016 - 6 weeks UNDETECTED AST 26 ALT 26 |
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isaing4 Twinvir story 8 years 7 months ago #8738
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We are in the same boat, Isaing. I also had a 9 million v/l and have not reached undetected at the 4 week test. Still waiting on the v/l results.
Hopefully it will not take much longer for us both. At 83 you are getting close! 3a F0 TX Naive
Started Tx 12/12/2015 Kingswood Sof/Dac Pre Tx - ALT 71 AST 40 V/L 9 million Day 11 - ALT 12 AST 15 4 week - LFTs normal - detected (same sample sent for v/l showed undetected) :/ 6 week - UND 12 week EOT - UND SVR4 SVR12 |
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isaing4 Twinvir story 8 years 7 months ago #8771
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Isaing, sorry I have not left you any well wishes on your thread yet!
Huge drop and heres wishing for an UND for you soon! All the best Deb Geno 1a, F1, tx naive, had it 35 yrs.
Started Cipla HepcvirL on 12/01/16 Starting VL 490,000 At 16 days in <15 4 week results: UND 8 week results: UND 5 weeks EOT alt 25 SVR 15 - Not Detected 6 months EOT - Not Detected |
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isaing4 Twinvir story 8 years 7 months ago #8789
You are 1b F0-1 and treatment naive. That gives you a 99% chance of SVR with 12 weeks Sof/Led: ION-1 100% (67/67) ION-3 98% (43/44) Aggregate 99.1% (110/111) Not bad odds. To reassure you here are some real results from a patient of mine... Week 0 7.8 million Week 2 598 Week 4 76 Week 5.5 < 15 Week 8 0 Week 12 0 SVR 4 0 SVR 12 0 Lots of testing because she was a doctor and one of my first patients. 5.5 weeks because she went on a cruise! Personally if I wanted an insurance blanket I would add some Simeprevir rather than treat for longer. The odds are on your side and you are chasing the last 1-2%. fixhepc.com/forum/experts-corner/602-100...mpossible-dream.html YMMV
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