Eight week treatment

This topic has 6 replies, 6 voices, and was last updated 8 years, 10 months ago by Geno1b4.

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1 November 2015 at 3:49 am #3133
Johnboy
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- Guardian Angel
@johnboy
http://www.natap.org/2015/EACS/EACS_23.htm

Seems to me that eight weeks treatment is not a financial decision after all. These are great results. Virtually 100% (one patient discontinued due to nausea).

I seriously wonder whether Daclatasvir (for G1 at least) would be as good over the short course. It has a higher log kill than Ledipasvir.

Nevertheless….. I will take each and every pill of my twelve week course.

I am “undetectable” at three weeks and am half through my twelve week course.

G1 58yo F1 54,000 viral load Relapser 2003/4 Sof/Dac started 21/9/2015
1 November 2015 at 11:28 am #3152
Joy
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@joy
Fantastic news Johnboy!
1 November 2015 at 12:04 pm #3154
emilio
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@emilio
Hi JB, We’re creating a research category when we get 5, are you happy for me to move this thread into it once I do this? Cheers Em
1 November 2015 at 12:06 pm #3155
emilio
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@emilio
Hey JB and forgot to say congratulations on your 3 week result. Mine was still detectable under 15 but not far off. Em
1 November 2015 at 2:47 pm #3164
zhuk
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@zhuk
Outstanding news johnboy, and congratulations!

Its nothing short of miraculous to read of the success stories posted here,..yeah the stats on paper are impressive but to read of you guys real-world successes, well its amazing tbh

I can only wish everyone here going for treatment the best of luck

GT1a since 1988, diagnosed 1990
F0, tx naive
VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 – 2.9
Started Mesochem sof/dac 12 weeks 01/01/2016
11/02/2016 – 6 weeks UNDETECTED
AST 26
ALT 26
1 November 2015 at 3:29 pm #3166
miko3
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@miko3
I seriously wonder whether Daclatasvir (for G1 at least) would be as good over the short course. It has a higher log kill than Ledipasvir.

Hopefully some answers to that question will come from the AASLD conference in mid nov.Like you I will continue to take my sof dac riba for at least 12 wks in the meantime.When you look at the size of some of the subcategories in these results the numbers are sometimes
very small.One must remember in trials like this one of the objects is to overcome the obstacle of the absurd costs Big Pharma are demanding.This criteria does not apply to the same extent when using generics.

Gen 1b 40yrs,tx naive, f3/f4.VL too high to quantify.
Started tx 12Oct.sof and riba India via greg.Dac from Mesochem.
4wk result virus not detected,all liver functions in normal ranges.
Only SE intermittent insomnia.Feel great and grateful otherwise
30 December 2015 at 12:41 am #7504
Geno1b4
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@geno1b4
@Johnboy
Great news and cheers to your new life
I’ve stumbled upon this hepc therapy calculator based on trial results on various genotypes.
Some trials are not big but still one can get a picture of how treatments worked.

http://hcvsvrpredictor.liverdoc.com/#/HCV

Genotype 1b & 4, F0/A1, failed Peg&Riba TX 2015,
22 Jan. 2016 – Back from Delhi with 12 week Ledifos supply 🙂 Thx to Parag
Started TX on 27.Jan.2016 – AST 41, ALT 59, GGT 39, ALP 74, VL 500.000, Fibroscan 6.8
19. Feb 2016 – ALT 14, AST 14, GGT 19, ALP 107
19. Apr 2016 EOT – Undetected 🙂
26. Apr 2016 (1 week after EOT) – ALT 14, AST 17, GGT 12, ALP 77
28. Aug 2016 (17 weeks after EOT) – UND, ALT 15, AST 12, GGT 5, ALP 39 🙂
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