Home Forums Main Forum Media & News Harvoni – decline of sales in U.S.?!

Viewing 15 posts - 1 through 15 (of 27 total)
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  • #17628
    Avatar photorohcvfighter
    • Guardian Angel
    • ★★★★★
    @rohcvfighter

    Hi Everybody,

    in the latest press release from Gilead (for the first quarter of 2016), available at http://investors.gilead.com/phoenix.zhtml?c=69964&p=irol-earnings, there is a strange information, that by compare with the first quarter from 2015, the sales for Harvoni declined in US, while Sovaldi sales increased slightly, while in Europe Sovaldi sales decreased. Looking at the numbers, the drop in sales for antiviral products seems quite big (US -$1 billion)

    Are perhaps US people knowing something more about the drug Harvoni than the rest of the world?

    Regards,
    RHF


    In fiecare an HCV ucide peste 500000 oameni.Medicamentele generice pentru hepatita C functioneaza. Nu deveni statistica! Cauta pe Google “medicamente generice pentru hepatita C”.
    HCV kills more than 500000 people every year. HCV generic drugs work. Don’t become a statistic.
    By sharing this Youtube video you might save someone’s life!
    My TX: HEPCVIR-L[generic Harvoni]-India
    SVR52 achieved

    #17629
    Avatar photoMeg
    • Topics: 3
    • Replies: 92
    • Total: 95
    • Guardian Angel
    • ★★★★★
    @meg

    Interesting question RHF.
    I was just checking their site too – but for info on the new drug to be approved by the FDA on June 28th.


    Blood transfusion in 1992 – Diagnosed in 2007
    Tx naive -G1b – F1
    VL 2.270.000
    ALT 40
    Start tx June 4th/2016 with DAAs – Sof/Led from India
    Bloods on two weeks of tx (June 18th)
    AST 17 – ALT 10 – GGT 19
    Virus UND
    Bloods on six weeks of tx (July 16th)
    AST 17 – ALT 8 – GGT 12
    Virus UND
    EOT on August 8th (did 9 weeks and 3 days)

    SVR 4 Virus UND (September 7th)
    AST 13 – ALT 5

    SVR 14 Virus UND (November 12th)

    #17634
    Avatar photoAriel
    • Guardian Angel
    • ★★★★★
    @ariel

    Thankyou for the interesting read
    It’s hard to say why a drop in sales. I’m certain it won’t be to do with the effectiveness or safety of the DAAs we have taken or are taking or for some, about to take. Like Meg I researched the new drug but information is sketchy.

    Interesting snippets from this pdf include Gilead stating “….the potential pricing pressure from additional competitive HCV launches or austerity measures in European Countries and Japan…..”

    I’m still arguing the generic case and recoil at Gileads profit margins as we all do.
    Another useful doc ty ROhcv for this
    Cheers from Ariel

    #17636
    Avatar photobeaches
    • Guardian Angel
    • ★★★★★
    @beaches

    Maybe it’s the generics :P


    Genotype 1a
    Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
    Harvoni treatment, started 19 March 2016
    4 week results Bilirubin 12 down from 14 pre treatment,
    Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
    VL <15 down from a lazy 6 million or so

    EOT Results
    Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

    12 Weeks post EOT
    Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
    Cured baby

    #17637
    Avatar photoGreedfighter
    • Guardian Angel
    • ★★★★★
    @greedfighter

    I also read that insurance companies continue to limit access to only the sickest patients, and that many are given only 8 weeks of treatment (less than 6 million VL) that is also cutting in to earnings.

    #17638
    avatar876.jpegGaj
    • Guardian Angel
    • ★★★★★
    @gaj

    The market certainly doesn’t seem happy with their performance. Big initial drop after the announcement with no recovery and in fact a slow worsening. This is a company that was at $1.20 in July last year with projections of $1.50 within 12 months. :evil:

    image-2-3-4-5-6-7.png


    G3a since ’78 – Dx ’12 – F4 (2xHCC)
    24wk Tx – PEG/Riba/Dac 2013 relapsed
    24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
    16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
    SVR7 – 22/06/17 UND
    SRV12 – 27/07/17 UND
    SVR24 – 26/10/17 UND
    :cheer: :cheer: :cheer:

    #17664
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Gilead’s share price is down 32% from a peak of $122.21 on 23 June 2015 pre generics to $83.62 today – post generics.

    ScreenShot2016-05-24at2.04.46AM.png

    Current market cap of $112 billion was $164 billion last year, so $52 billion dollars worth of greed has now dissolved before investors eyes.

    $50 billion – that’s $50,000,000,000 in investor losses, and last year 500,000 patients died of a now curable illness.

    Coincidentally it works out at an investor loss of $100,000 per patient death, more or less exactly the same as the cost per cure.

    Karma?


    YMMV

    #17666
    Avatar photobeaches
    • Guardian Angel
    • ★★★★★
    @beaches

    I always say to anyone who will listen (and to others as well) that if you own shares in big pharma you are profiting from death and misery


    Genotype 1a
    Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
    Harvoni treatment, started 19 March 2016
    4 week results Bilirubin 12 down from 14 pre treatment,
    Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
    VL <15 down from a lazy 6 million or so

    EOT Results
    Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

    12 Weeks post EOT
    Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
    Cured baby

    #17669
    Avatar photomgalbrai
    • Guardian Angel
    • ★★★★★
    @mgalbrai

    A lot of factors could be contributing to this decline in “blood money”.
    I would like to think generics is a major one.
    m


    Curehcvnow@gmail.com
    http://forums.delphiforums.com/generichcvtx

    G 1a F-1
    Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
    11/17/15 4 wk lab ALT 17 AST 16 <15
    11/18/15 Started Harvoni
    12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
    1/14/16 Fin. Tx
    7/07/16 UND SVR 24

    #17670
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Realistically generics are only a tiny contributor and represent one component of competition, but logically only a trivial part because if you have to chase generics, then by definition you’re not in the (potentially) funded population.

    And it’s not undercutting pricing from Abbvie that’s driving it either – their volumes are down too.

    http://www.bidnessetc.com/58797-gilead-sciences-inc-and-abbvie-face-declining-hcv-scripts/

    Effectively bankrupting the major payers like the VA and Medicaid is the primary cause.

    Gilead and other pharmaceutical companies are strangling the geese that lay the golden eggs.


    YMMV

    #17671
    Avatar photoGreedfighter
    • Guardian Angel
    • ★★★★★
    @greedfighter

    It seems to me the only way these prices will ever come down, is to make a legal case that these companies are ‘profiteering’ or ‘price gouging’.

    Seems a lot of politicians are either corrupt or cowards.

    #17693
    Avatar photoVororo
    • Guardian Angel
    • ★★★★★
    @vororo

    Another reason for the fall in share prices could be investor fears of pending class actions:

    https://www.chimicles.com/gilead-sovaldi-lawsuit

    https://www.schmidtandclark.com/sovaldi-lawsuit

    http://www.law360.com/articles/603544/pa-transit-agency-slaps-gilead-with-price-gouging-suit

    (see also https://www.chimicles.com/wp-content/uploads/2014/09/Gilead-FAC.pdf)


    Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
    Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
    Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
    Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).

    #17696
    Avatar photomgalbrai
    • Guardian Angel
    • ★★★★★
    @mgalbrai

    I’m sure there were quite a few people with enough money just to self-pay when Harvoni first came out. The “Pamela Andersons” and other financially blessed suffers just bought it.
    m


    Curehcvnow@gmail.com
    http://forums.delphiforums.com/generichcvtx

    G 1a F-1
    Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
    11/17/15 4 wk lab ALT 17 AST 16 <15
    11/18/15 Started Harvoni
    12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
    1/14/16 Fin. Tx
    7/07/16 UND SVR 24

    #19217
    Avatar photorohcvfighter
    • Guardian Angel
    • ★★★★★
    @rohcvfighter

    If one looks today at the stock market for Gild, will notice a nice downward trend in the last month (ref. Point 25.04.2016 till today).

    Would I be too malicious if I would wish to GILD a nice and safe trip to the bottom (0$)? I mean, I am concerned about their safe journey in a similar way they care about ours…..


    In fiecare an HCV ucide peste 500000 oameni.Medicamentele generice pentru hepatita C functioneaza. Nu deveni statistica! Cauta pe Google “medicamente generice pentru hepatita C”.
    HCV kills more than 500000 people every year. HCV generic drugs work. Don’t become a statistic.
    By sharing this Youtube video you might save someone’s life!
    My TX: HEPCVIR-L[generic Harvoni]-India
    SVR52 achieved

    #19220
    Avatar photomgalbrai
    • Guardian Angel
    • ★★★★★
    @mgalbrai

    Gilead stock is currently trading at $83.04, down from $123.57 a year ago. A lot of things have happened since last June:
    As I mentioned earlier, the people who had the money in the US, bought Harvoni as soon as it became available. That market is pretty much gone.
    The insurers covered many of the sickest patients early on. There are a lot of really sick people who don’t have insurance or have bad insurance coverage, however. Many are still waiting for access to treatment.
    The competition has increased, forcing Gilead to negotiate lower prices for insurance companies as well as entire countries. Australia is a good example.
    In addition, generics have come into play. I imagine the health tourism business in India is flourishing.
    There are other factors I’m sure, but Gilead’s share price seems to have stabilized around $80.00. I imagine it will stay there until someone comes up with a much shorter treatment regimen.
    m


    Curehcvnow@gmail.com
    http://forums.delphiforums.com/generichcvtx

    G 1a F-1
    Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
    11/17/15 4 wk lab ALT 17 AST 16 <15
    11/18/15 Started Harvoni
    12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
    1/14/16 Fin. Tx
    7/07/16 UND SVR 24

Viewing 15 posts - 1 through 15 (of 27 total)
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