Thanks Joy, really appreciate your well wishes. Great to hear how much better your pain is after tx; as you say we get habituated to thinking this is life as “normal” – when in fact none of us knew what normal was at all heh.

Similarly, how much of our emotional/mental issues are hep-related and how much is endogenous…this is also going to be an interesting one to find out. I had a lot of depression-issues in my young life before contracting hep, but I can only think they would have been exacerbated afterwards.

I have a question, does the sof/led or sof/dac treatment affects the nervous system too?

If yes, the gurney is difficult during the treatment as in beginning there are two contributes HCV and The meds

Very interesting this extrahepatic involvement in hepatitis C.
In the last 10 years before being diagnosed with hepatitis C, I had strange pains.
I investigated, but no explanation. So I got to get used to them.
These periodic pain, comes and goes, in the diaphragm / stomach, as if you have something you can not swallow. Ultrasound / Endoscopy = result = unknown cause! Periodical pain, comes and goes, back at the base ribs. The pain woke me up, because that always happens at around 2 to 3 am. Rheumatologist / x-ray= result = unknown cause!
In both cases only help was heating pad. And patience … it usually does not last longer than 1 hour.
I hope the pain does not come back if I will cure hep C!

I’m really feeling optimistic after reading this. All these conditions that have hit me in the past couple of years – like being described here, especially the peripheral neuropathy, joint pain, night pain is the worst and causes insomnia, a lot of things investigated but told ‘it must be age’!!

A couple of years ago I was building bird aviaries, cages, gardening and maintaining a massive property – all on my own. Then went downhill rapidly and had to move to smaller place, lower maintenance, God I’m crippled in pain after mowing the lawn, barely 1/4 the size of previous. No chance building stuff anymore.

The idea I may be free of some of this is awesome! Like you Zhuk I know I can’t do anything about spinal nerve impingement & arthritis but would love not to have burning hands and feet 24/7 inch:

mm the spinal stuff is weird, I feel like my spine is changing even after 4 weeks, I can now crack my neck again without restriction, getting back into yoga and stuff, I had bad back issues before, I know it will take a long time to address these, but feel now like I can move again, doing headstands and serious back bends again after being off the yoga mat for many years.
Feels like I am living again Chejai, you go for it mate

I agree Enkel, given that the Vagus Nerve (AKA Wandering-from Latin- Nerve) is a major cranial nerve and the longest in the body because when it exits the brainstem it branches off to our throat, thorax and abdomen covering our organs and reporting info back to the brain. If it picks up signs of ‘infection’ it reports to the brain and it sends out an immune response. When you have a chronic infection like HCV that affects more than the liver, then the body is in a chronic state of immune response. The Vagus Nerve is a major part of our nervous system so you can imagine how dysfunctional many systems in our bodies become. It has both sensory and motor functions and controls our breathing, speaking, swallowing, heart rate, sweating, digestive processes and more.
Yes, one thing for sure I’m learning is that having chronic HCV, no matter what level of liver disease that might be present, so many symptoms and conditions e.g. peripheral neuropathy, chronic fatigue, fibromyalgia, and cognitive impairment -‘Brain Fog’ – are real and related directly to the virus. Yet, so many GP’s and some Specialists too, dismiss them and don’t consider a connection, despite the fact there is actually a lot of research saying so.
I understand it’s hard work for GP’s to keep up with all the different issues patients present everyday and I’ve been ‘dismissed’ so much over the years with my concerns that ‘something’s not right’ you just end up living with it.

I hardly slept at all last night from the pain in my right arm – like someone dragging a hot blade down my forearm, pins and needles and burning in my hands, can’t get comfortable, doze a few hours have wild dreams and wake in pain again! Endless cycle…

Jimmy6429 – yeah I miss Yoga so much. I practised on/off for over 25 years, had to stop about 2 yrs ago because of the pain in my wrists; I don’t miss the looks from the embarassing clicking sound of my right hip popping in & out and the squishing sound from my right knee during many postures
But if I can look forward to less pain and more flexibility again that would be awesome!

Yeas zhuk the doctors told me i was just neurotic and stop wasting their time. Evrn when i presented with excema arthritis rh factor and multiple other phisical symptons and yes enkel vagus nerve is definetly involveddue to viral load in brain is my guess.
Jim

How impressive is that, Wayne – great to hear!

All the best of luck for the rest of your treatment