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  • 5 October 2015 at 6:14 am #1810
    Avatar photocrazy8
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    • Recovery Champion
    • ★★★★
    @crazy8

    Hi, I was hoping someone could tell me how to go about procuring a 24 week supply of daclatasvir and sofosbuvir given that I’m only allowed to import a 12 week supply?, I assume the 24 week course would need to be taken without interruption of medication, can someone shed any light on this dilemma?, the only logical play out of this scenario to me would be to stockpile the first 12 week supply and then import the second 12 week course after the original 3 month medication was due to be used up?,

    i also would like to applaud the team at ‘FixHepC’ , I and many more now have a reason to hope, I put no faith in cabinet approval for a PBS listing, and who could blame them at the price the pharmaceutical companies are asking.

    GT 3, F3, Contracted 1993 Tx Naive
    V/L 1,267,000 AST 67 ALT 65 6/10/15
    commence Sof/Dac (Mesochem) 6/11/15
    AST ALT normal 24/11 *
    *V/L UNDETECTED 24/11*

    5 October 2015 at 6:41 am #1811
    Johnboy
    • Topics: 16
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    • Total: 91
    • Guardian Angel
    • ★★★★★
    @johnboy

    You can import three months at a time. This does not mean you have to wait three months to import your next lot.

    No issue my friend. As Meso have closed their doors to individual supply I would imagine Fixhepc will be your provider. In that case I think you will find they have this issue under control

    If you are using Indian sofosbuvir through Greg Jefferys then the same would apply.

    G1 58yo F1 54,000 viral load Relapser 2003/4 Sof/Dac started 21/9/2015

    5 October 2015 at 10:19 am #1823
    Avatar photoNadia
    • Guardian Angel
    • ★★★★★
    @nadia

    Hi Vicki,
    I’m not sure about supplements. My nurse was going to check with the pharmacist about vit D and calcium I am prescribed but for now I’ve stopped taking them just in case.
    I think Dr Freeman is the best person to ask this question.

    Virus not detected from 14.10.2015

    5 October 2015 at 12:34 pm #1837
    Johnboy
    • Topics: 16
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    • Guardian Angel
    • ★★★★★
    @johnboy

    Funny you mention magnesium calcium and vitamin D

    I am not a believer in artificial vitamins, especially vitamin D. You can not synthesise sunshine IMO. I also believe it is not Vit D but D2/3. I believe they are carcinogens.

    Here is something for you to think about:
    The chlorphyll molecule and the red blood molecule are identical except they have different central atoms. Chlorophyll has a central atom of Magnesium, red blood has a centre of iron. Green “plant blood” is changed to red human blood cells by the action of sunshines voltage on the skin. The by product of this process is calcium. So you see all these things are connected directly. What you need is more sunshine and more raw fresh greens in your diet. It’s the natural way to build red blood cells, get magnesium, get calcium and get the correct vitamin D.

    This is a very basic description but hopefully it entice you to find your healing in the way nature provides.

    Green is your medicine. Sunshine is your friend.

    G1 58yo F1 54,000 viral load Relapser 2003/4 Sof/Dac started 21/9/2015

    5 October 2015 at 12:40 pm #1840
    Avatar photoNadia
    • Guardian Angel
    • ★★★★★
    @nadia

    Unfortunately I live in the UK and already have osteopenia. Low vit D level is associated with the Hep C. Hopefully once the virus is gone, my vit D level will go up.

    Virus not detected from 14.10.2015

    5 October 2015 at 1:07 pm #1842
    Avatar photoLondonGirl
    • Guardian Angel
    • ★★★★★
    @londongirl

    Sunshine is indeed my friend, but also in UK. The sunshine here is not good enough, if we see it at all ! We can get cheap flights to warmer climates easily, I need my VitC fix frequently and always feel a huge improvement. Last bloods, my VitD result showed just enough, that was after taking suppliments over last winter.

    Magnesium is a v interesting one, it seems to help many ailments associated with HepC. Although my Dr said it was ‘unlikely’ I have found it has helped me personally.

    Edit: Please note I am not on treatment, would also be interested in DrF’s take on that

    GT1a Dec14 F2/8.7 VL 900000-2.5M
    Jan16 Hepcivir-L MonkMed/Redemption
    Baseline: VL 913575 Alt 76 Platelets low
    Wk2 VL1157 Alt 23
    DET Wk 8 VL 32 Alt19 ‘In the slow lane’
    June16 Fibro 5.7 F0/1 LIF 1.5
    Wk 11 VL<12 Alt 13 Det/Unq
    Extending tx 12 wks Mylan Sofo/Dac MonkMed
    Wk 14 VL <12 Det/Unq
    Wk 16 VL UNDETECTED
    Wk 22 + 4 Wks Sunprevir FixHepC
    Wk 24 UNDETECTED Alt 13
    Wk 12 post tx SVR12 Wk 26 SVR24
    Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC

    5 October 2015 at 1:08 pm #1843
    WILSON1
    • Topics: 0
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    • Acolyte
    • ★★
    @wilson1

    A site you may get help from.It’s not all things but is pretty extensive. I check “view all” to navigate.
    http://www.hep-druginteractions.org

    5 October 2015 at 1:12 pm #1844
    Johnboy
    • Topics: 16
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    • Guardian Angel
    • ★★★★★
    @johnboy

    There is a very handy app which is great too. It cross references many drugs for interactions with HepC meds.

    It is called “Hep Ichart”

    It is from the the university of Liverpool

    G1 58yo F1 54,000 viral load Relapser 2003/4 Sof/Dac started 21/9/2015

    5 October 2015 at 2:30 pm #1850
    Avatar photoVicki
    • Topics: 5
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    • Recovery Champion
    • ★★★★
    @vicki

    I’m hearing you Johnnboy, I eat so much fresh green from my garden. I get a fair bit of sunshine here on the on the South Coast of Australia.

    I’m not big on supplements but since taking manesium my nasty migraines have abated.
    I can get a rub on magnesium rub on gel (though expensive)

    5 October 2015 at 2:35 pm #1851
    Johnboy
    • Topics: 16
    • Replies: 75
    • Total: 91
    • Guardian Angel
    • ★★★★★
    @johnboy

    Whatever works for you has got be good eh!

    If I had migraines I would take anything that worked too :)

    G1 58yo F1 54,000 viral load Relapser 2003/4 Sof/Dac started 21/9/2015

    9 October 2015 at 11:14 am #2065
    Avatar photoVicki
    • Topics: 5
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    • Recovery Champion
    • ★★★★
    @vicki

    Hi all,

    I’m 2 1/2 weeks into Sof/Dac 12week treatment. So far so good. :)

    I’m wondering about times to take the Sof/Dac?
    Right now I’m taking both the Sof and Dac together in the morning with a light healthy breakfast.
    I saw mention that Dr. Freeman had published a page on this site about foods to avoid when you take your cure.
    I can’t seem to find it
    I have thoroughly read the “Consumer Medication” directions and they don’t mention diet.

    9 October 2015 at 12:14 pm #2068
    Avatar photoLife
    • Guardian Angel
    • ★★★★★
    @life

    Hello Vicky, this is Life!!! :)

    So you take both at the same time in the morning, is that correct?

    Thanks for replying!!!

    Ohw, I see that you asked the same question…i’m also looking for the foodlist, I’m starting on monday!!

    Thanks

    9 October 2015 at 2:47 pm #2071
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hi Vicki,

    The big NO NO with Dac is Grapefruit juice which inhibits the enzyme CYP3A4 which breaks down the Dac. As a result of this inhibition the Dac levels build up, as do the sides.

    You may find this page helpful

    http://www.ganfyd.org/index.php?title=Inhibitors_of_CYP3A4

    Here’s Wikipedia’s overview of it https://en.wikipedia.org/wiki/CYP3A4

    YMMV

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