How manny GT3’s on this forum are cured?

[AK123]

Hello and good luck to all currently on treatment, including myself!

My burning question is treatment length (non-cirrhotic)- 12 weeks or more on Daklinza/Sovaldi? I can’t seem to find trial results that show different treatment time-frame results. Ie. 16 weeks, 24 weeks as alternatives. Anyone have an idea?

It would be great for those retreating for Genotype 3 to mention their new drug combination and length too, please.

[wilko johnson]

Hi AK123, I was advised by Dr Freeman to extend my 12 weeks tx to 16 or 18 weeks as results suggested better outcomes. This was back in April. So I did 16 wks and have just reached svr 24. I had no cirrhosis and fibroscan score of 2. Hope this helps. Wilko

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gt3 started sof dac jan 2016 now 48 wks svr. not the real wilko johnson just have the same real name. shropshire uk

[Donna]

I’m doing 12 weeks ( finish 28/11/16) I did think about extending treatment… but decided on 12 weeks.
Undetected at 3 weeks into treatment… I had no cirrhosis and fibro scan F1

[LondonGirl]

Hi AK123, Maybe you could put some more info re your VL pre tx and any previous treatment? Then people with a similar status can tell you of their own experience.

There is a patient called rightsaidfred on this forum, GT3 and they are now now clear, They may be able to advise you, I believe RSF extended over the 12 weeks, just to be sure.

Of course, you can talk to Dr Freeman of FixHepC for advise and Dr Debasis at MonkMed via care@monkmed.com

They are the best in the HepC world with unbiased excellent advise.

I am not GT3 but I was a slow responder and their advise and support was outstanding. (I am currently SVR12 thanks to their EXPERT advise).

Good luck and my advise is, seek advise with these two experts if you have any concerns. It can all be easily done with a telephone or skype appointment.

Best wrishes

LG

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GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC

[AK123]

Thank you LondonGirl and others for your kind sharing of advice and personal treatment stories. I have had an informative reply from Dr Freeman (posted under ‘Sovaldi/Daklinza-side-effects and treatment duration’, which has been a marvellous help as well. All the best!

[LondonGirl]

and there’s another GT3 success story in wilko johnson

Congratulations wilko mate

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GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC

[MtGoat]

I’m another G3a who is cured. Just got my SVR24. Did 18 weeks TX

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Cheers
3a for 35 years
Dx 1996, tx naive, ALT 46 AST 38 VL 140K
Started Sof/Dac 1/23/16
Kingswood generics AUS
2/19/16 4wk lab HCV Undetected ALT 14 AST 19
EOT 6/1/2016
TX was 18 wks (w/some 1/2 doses & 1 skip dose after 11 wks
while waiting for +6 wks to arrive)
SVR4 6/30/16
SVR12
SVR24 Redeemed

[Gaj]

Congratulations on your SVR24 MtGoat!!!

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G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND

[MtGoat]

Thanks Gaj. What’s happening for you? Are you waiting for a 3 part combo to become available?

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Cheers
3a for 35 years
Dx 1996, tx naive, ALT 46 AST 38 VL 140K
Started Sof/Dac 1/23/16
Kingswood generics AUS
2/19/16 4wk lab HCV Undetected ALT 14 AST 19
EOT 6/1/2016
TX was 18 wks (w/some 1/2 doses & 1 skip dose after 11 wks
while waiting for +6 wks to arrive)
SVR4 6/30/16
SVR12
SVR24 Redeemed

[Donna]

Lovely news MtGoat

[Fara]

Great news MtGoat on your SVR24!!! ……Best wishes with continued health and happiness!..Fara

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HCV since 35-40yrs., GT 1a , Dx 2004; VL 4-5 mil, F2-3
Tx sof/led started 3/4/16
4wks VL <15
9 weeks VL UND, ; Alt-15,Ast-13
16 weeks VL UND Alt-20, Ast-22;
EOT 24 wks UND
SVR 4 UND
SVR 12 UND, Alt.15, Ast. 17
SVR 24 UND

[CC2B]

great news! MG
Congrats

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GT2b diagnosed 10/2015
since: unknown
11/20/15 VL= 214,070
12/4/15 ALT=18 AST= 24
1/16/16 started sof/dac
2/13/16 @4wks VL=UND ALT=13 AST=22
3/12/16 @8wks VL=UND ALT=10 AST=18
4/9/16 EOT VL=UND ALT=11 AST=19
9/23/16 SVR24 ALT=11 AST=22

[Gaj]

Thanks MG. Having tried twice with Dac combos I’ve decided to look for a three way to really nail it this time. Currently doing something I’ve had plenty of previous practice at …….waiting! There are some good options coming through for relapsed GT3s but time seems to drag.

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G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND

[Vororo]

For me (probably life-long GT3), Sof+Dac worked like a dream. Please see my signature.

… No, not a dream. It’s real!!!

Oor Wullie.

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Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).

[MtGoat]

Well Gaj, I am a fan of yours so, I’ll be waiting in the wings to follow you through whatever comes after this. I don’t want you to wait & I saddened that you’re waiting.

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Cheers
3a for 35 years
Dx 1996, tx naive, ALT 46 AST 38 VL 140K
Started Sof/Dac 1/23/16
Kingswood generics AUS
2/19/16 4wk lab HCV Undetected ALT 14 AST 19
EOT 6/1/2016
TX was 18 wks (w/some 1/2 doses & 1 skip dose after 11 wks
while waiting for +6 wks to arrive)
SVR4 6/30/16
SVR12
SVR24 Redeemed

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