Hi DennisP and welcome.

If you read the article that Dr Freeman linked in the following post you will see that it states:

“In patients with HCV gentotype 3, the new drug did better in sustained virologic response and “hints of lesser harm” in that there were fewer reports of adverse events.”

It doesn’t state how much better the SVR rate is but from what I have read elsewhere probably in the order of a couple of percent.

https://fixhepc.com/forum/hcv-research/1348-velpatasvir-not-better-than-earlier-drugs.html#22381

Hi!
I was gen 1b and the results are being updated in my signature. I’m 1m into treatment.
I read of several (>5) gen 3 people who were cured with sofosvel on hcv.ru Probably no difference btw the two generics (sofosvel and panovir – which I’m being cured with now).
Otherwise, check the trial results. On sof/vel and on pibrentasvir/glecaprevir.
As far as I see, there is no reason to defer treatment as many retreatment options are coming – and you never know what works.
If I were you I’d sof/vel. And if were unsuccessful, retreat with abbvie’s combination. However, read everything carefully. Individual experience does not count. Trial data is a bit more reliable.
There is few data and you can just read through and see what works for you.
Wish you best luck with your treatment.

Good Luck on treatment Dennis. I’ve only heard of good success rates with Sof/Vel.
Where do you live? I’m in USA and thinking about ordering from Beacon also.
Thanks
happi

I am genotype 3A and on generic Epclusa. I plan on taking it the full 24 weeks just to be sure it is gone, although I know results have been shown to be effective in treating it not as long. You have already finished your 12 weeks by now. Your post was 4 months ago. Hope to hear how you are doing.

Hi JoannaCH and welcome,

Firstly congratulations on starting your treatment. I had G1a so my treatment was a little different to yours but thankfully these different medications are leading to the same outcome – the eradication of the virus.

There are G3s who have successfully treated with Epclusa and you’ll find one will hop on the forum soon to share their experiences on that particular medication.

In the meantime we’re with you. Roll on October 24th!

Hi sixtieschild,

Congratulations on your results. I know how wonderful it is to hear the news that it’s a great big negative.

Thanks for sharing your story. It might be the one that tips the balance for someone who needs treatment but is worried about the legitimacy of FixhepC. As those of us that are now cured know it may seem too good to be true but it really is good and true.

I also had Hep C for 30+ years and had children that may have been infected. One son is carrying antibodies suggesting that he was exposed to the virus but his body managed to clear it. Ahh the guilt of a mother!

Good to hear that things are returning to normal for you – it takes a while for the drugs to get out of your system. That fatigue and brain fog is a killer. Sometimes it’s hard to believe how bad I felt and how much the virus affected my life but now that it’s gone I think it’s really important to be thankful and look forward.

It’s great that you had some good support around you. Take it easy and there’s nothing wrong with a bit of Netflix every now and again.

Coral

hi. Yes I took epclusa and my viral load became undetectable within 4 weeks. It’s 4 months since I began treatment and my labs are still undetectable.

The side effects were difficult but worth it. Worst side effects were fatigue and confusion. I had fatigue almost all day long, and I would pass out mid sentence sometimes and if I sat for more than 10 minutes. The confusion would come and go. I would forget things like which day of the week it was. Having long conversations was difficult. It was difficult for my thoughts to continue that long.

Other side effects. In the first month I had nausea. I had dizziness throughout treatment. So dizzy I had to lay on the couch and I couldn’t lift my head for about half hour. I also got a blister rash that would come and go. Occasional weakness too.

Again, all of these side effects were worth the result of the treatment. I did not drive during the 3 months due to my extreme fatigue and confusion and I regularly had friends and family help with my kids and help take care of me.

Good luck it has a really high cure rate so stick it out to the end. Also, I was told my side effects were more intense than some experience.