Home Forums Main Forum FixHepC Admin Q & A Things to avoid on treatment?

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  • #10867
    wilko johnson
    • Topics: 5
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    • Recovery Champion
    • ★★★★
    @wilko-johnson

    Can anyone give advice on the following; Avoiding fats while on daclatasvir? Am I ok to carry on with nicotine replacement while on tx and anything else to avoid? I am aware of avoiding grapefruit. thanks.


    gt3 started sof dac jan 2016 now 48 wks svr. not the real wilko johnson just have the same real name. shropshire uk

    #10870
    Avatar photoLondonGirl
    • Guardian Angel
    • ★★★★★
    @londongirl

    Hey Wilko :)
    Seville oranges and I think, marmalade. The best of luck with your treatment, so pleased that you are finally sorted :+1:


    GT1a Dec14 F2/8.7 VL 900000-2.5M
    Jan16 Hepcivir-L MonkMed/Redemption
    Baseline: VL 913575 Alt 76 Platelets low
    Wk2 VL1157 Alt 23
    DET Wk 8 VL 32 Alt19 ‘In the slow lane’
    June16 Fibro 5.7 F0/1 LIF 1.5
    Wk 11 VL<12 Alt 13 Det/Unq
    Extending tx 12 wks Mylan Sofo/Dac MonkMed
    Wk 14 VL <12 Det/Unq
    Wk 16 VL UNDETECTED
    Wk 22 + 4 Wks Sunprevir FixHepC
    Wk 24 UNDETECTED Alt 13
    Wk 12 post tx SVR12 Wk 26 SVR24
    Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC

    #10872
    avatar876.jpegGaj
    • Guardian Angel
    • ★★★★★
    @gaj

    Hi Wilko,

    Couple of threads about things to avoid on Daclatasvir, just be aware in the second one that only the first four fruits are really a problem and garlic is probably since disproved but just don’t eat several raw cloves at the same time as the Dac.

    http://fixhepc.com/forum/drug-interactions/108-daclatasvir-warning-interactions-cyp3a4.html

    http://www.ganfyd.org/index.php?title=Inhibitors_of_CYP3A4

    Regarding fats, there are some warnings about that going around but the only research I’ve seen involved taking it directly after a meal containing very high fat (from memory +30-40g?) in which case not as much was absorbed by your body. They suggested it wouldn’t be a problem on normal diets. You can take Sof & Dac with or without food so if with then just make it a low fat meal. OTOH Ribavirin should be taken with some fat, in which case you may want to take It at a different time to the other meds.


    G3a since ’78 – Dx ’12 – F4 (2xHCC)
    24wk Tx – PEG/Riba/Dac 2013 relapsed
    24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
    16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
    SVR7 – 22/06/17 UND
    SRV12 – 27/07/17 UND
    SVR24 – 26/10/17 UND
    :cheer: :cheer: :cheer:

    #10875
    wilko johnson
    • Topics: 5
    • Replies: 47
    • Total: 52
    • Recovery Champion
    • ★★★★
    @wilko-johnson

    Thanks Gaj, I’me taking my meds in the mornings, no riba required for me. So I can have double cream on me pud at evening meal!! Thats great , and I do like me gaalic in my cooking, usually at evening meal too. Cheers.


    gt3 started sof dac jan 2016 now 48 wks svr. not the real wilko johnson just have the same real name. shropshire uk

    #10946
    Avatar photoSirchinenge
    • Guardian Angel
    • ★★★★★
    @sirchinenge

    Great news they have Arrived at last…………..:)

    Hopefully, you have a easy time whilst on treatment I have my fingers crossed for you.

    In no time you’ll be joining us on the Undetected bench and soon after cured.

    Good luck.


    Sob/Dac from Oct 29 2015
    Geno 1b
    Fiberscan 9.9 Pre treatment
    Fiberscan 7.4 week 10
    VL 1.3 million pre treatment
    Week 2.5 VL 96
    Week 5.5 VL 17
    Week 10 VL UD
    SVR 3 UD
    SVR 16 UD
    Cured:
    All liver functions in normal ranges.

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