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Hi Stew-H,
Sorry to hear things could be better.
It would be worth having a Berroca a day as peripheral neuropathies can be related to B deficinecy.
The water retention ought to be treated with a diuretic like lasix or spironolactone – that will get rid of it and make things more comfortable.
Yes, sadly for some people the effects remain.
If it had not been for people like you accessing generics, and us treating the transplant list with generics Australia might not have got such a good deal quite as quickly. It took the pressure off and let our Government negotiators negotiate hard.
It sounds like you are being looked after but maybe there is a bit of tuning up to be done. I’m happy to run a second opinion for you and see if I’ve got any nuggets of wisdom to toss in your general direction.
YMMV
Trust in the statistics Cherr1985. Chances are it’s just onward and upward for you now.
Best wishes
James
YMMV
3 April 2020 at 8:38 am in reply to: Cirrhosis and Resistant Hep C – New Symptoms are they serious? #29773There are quite a number of options, and to a degree they are all “suck it and see” in that some work great for some patients and not so great for others.
The full list is here: https://www.mayoclinic.org/diseases-conditions/psoriatic-arthritis/diagnosis-treatment/drc-20354081
We would usually start with methotrexate but that might not be the best idea in you. As you can see there are stacks of options and it’s really something best managed by a rheumatologist. Not only do they have expert skills in this area they are also allowed to use stuff GPs are not.
YMMV
Hello tototo,
Thanks for sharing your experience. It’s so much more real for people to hear it direct from the horse’s mouth as it were, rather than from a doctor.
Best wishes
James
YMMV
Hello Curl77,
While this is speculative, your azathioprine is quite possibly protective.
There is little doubt that both chloroquine and hydroxychloroquine help and the thing that kills people is a cytokine storm that causes the pneumonia.
It would be wise to stop the Candesartan while questions remain about its safety.
YMMV
Hi Kris,
The manufacturers decided it would be easier for patients to take 3 smaller pills than one big one so I doubt you will need to make them even smaller. You can, if required, crush them but they will taste foul – like the taste of a Tylenol/Panadol if you chew it.
If you’ve only had Hep C for four years your liver will not have much damage and will recover fully.
I have a prediction – you will take the pills, you will get cured, and you will ook back and wonder what your were worrying about.
How can I say that? Well, I’ve treated nearly 4000 Hep C patients and that’s the way the story goes for just about everyone.
The great thing about this forum is that you are not alone. Hep C is not the sort of thing most people talk to their friends about but here you can ask anything and you’ll find sympathetic support from people who been in your shoes and walked the walk.
While I can’t promise you a prince or a princess at the end of the journey, these new drugs are a bit of a fairytale and there is a lot of the “lived happily ever after”.
YMMV
Hi Kris,
The Mavyret pills are quite small. It could have been 1 big tablet but they made it as 3 little ones to make swallowing them easier.
While no medication is 100% side effect free Mavyret gets pretty close to that ideal. Most people cruise through treatment without any problem whatsoever.
YMMV
That’s fantastic news joy2world.
Maviret is great with very little in the way of side effects so don’t sweat it too much. Get a glass of water, swallow the first 3 pills, do that every day and it will be over almost before you notice.
YMMV
Hello p711,
Hep C is not the sort of disease you go to bed with and wake up dead. It’s a slow progression over time so there is plenty of time to get things sorted.
Do you know what the fibroscan result was? It is usual expressed as a number like 7.4kPa
Really, the key question for the specialist is what can you get me for retreatment and when. What country are you in?
I’d expect your pains are anxiety-related, or totally unrelated to the Hep C. It may be the virus growing back and annoying your liver but that usually happens quite promptly on stopping the tablets.
A good healthy diet, exercise, enough water, enough sleep, don’t smoke or drink too much alcohol remain the basis of good health. Relationships are also important and that includes your relationship with yourself (don’t beat yourself up about the past) and your friends and family.
YMMV
Hello Cherr1985,
Don’t worry – taking 2 doses on the same day is not a toxic overdose and 83 days of total treatment will be just fine.
Best Regards
James
YMMV
Hello tellietubbie,
Itching probably relates to an increased level of bilirubin and suggests your Fibroscan might be F4 (>12.5kPa). That potentially has some impact on the choice of treatment, best duration of treatment and if we should consider Ribavirin.
In a perfect world we have full blood count, liver and kidney function results.
In patients with cirrhosis, we like to have an AFP as cirrhosis carries a 3% per year risk of liver cancer and this generally shows up with an elevated AFP. Treated early we can fix it. Leave it too late and it sadly becomes get your affairs in order time.
The best way to proceed would be for you to book an online appointment with me so we can go over it all together. https://gp2u.com.au/
Now, for the really important question: Is your favourite Tinky Winky, Laa-Laa, Dipsy or Po?
YMMV
Hi p711,
Sorry to hear about that.
The sad reality of a success rate of 95% is that is also a failure rate of 5%. That means there is a 1:20 chance the treatment does not work.
For a person cure is 100% cured or 100% not, so it’s not really 95%. It’s 19 cured, 1 not cured.
Don’t panic. GT1 is easy to retreat and you will have about the same odds of cure next time around. You will probably be offered Vosevii and that’s great stuff.
This post of mine talks about resistance:
https://fixhepc.com/blog/item/118-why-does-hepatitis-c-treatment-fail-sometimes.html
This post talks about resistance:
https://fixhepc.com/blog/item/101-hcv-retreatment-101-in-plain-english-part-1.html
Please have a read and then feel free to ask any questions you have here.
It is not the end of the world. It happens. Mostly it’s pretty easy to get it fixed.
YMMV
Hello sudjoy,
No. Himalayan Rock salt is basically ordinary table salt – NaCl
“Chinen Salt” is a salt derived from Berberis sp. plants (commonly known as the Barberry plant).
https://www.quora.com/What-is-chinen-salt-used-for
Here is a scientific overview of Barberry extracts
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678494/
YMMV
Those results look great Sven.
Thank you for your kind words.
I’m really sad to hear about your dog passing on. There are no words…
YMMV
Hi Jimmy6429,
Great to hear from you! Thanks for checking in.
I know it’s true but it’s hard to believe we’ve been doing this for going on 5 years and patients are getting to SVR208 and beyond.
I reckon at 4 years we can definitely ditch the “Sustained Virological Response” and call it cured.
YMMV
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