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  • 11 November 2015 at 7:20 pm #3693
    nuribeslen
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    • Novice
    • ★
    @nuribeslen

    Could you please share which genotype whıch generic you use and what is your starting HCVRNA and day 14 result. İf we share this may be we clear the confusion about new generics coming day by day.

    12 November 2015 at 12:29 pm #3727
    nuribeslen
    • Topics: 2
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    • Total: 3
    • Novice
    • ★
    @nuribeslen

    I want to use twinvir but there is not enough shared and experinced patient in this forum

    12 November 2015 at 12:37 pm #3728
    Avatar photoklhilde
    • Guardian Angel
    • ★★★★★
    @klhilde

    What genotype are you?

    Twinvir works well for types 1a, 1b, 2 and 4 … not quite so good with type 3.
    Twinvir is from Incepta from Bangladesh.
    Incepta also has Hopetavir (sofosbuvir), and the new Virodacla (daclatisvir)
    The sof/dac combo is better for type 3 and works very well across all genotypes.

    12 November 2015 at 12:40 pm #3729
    Avatar photoLondonGirl
    • Guardian Angel
    • ★★★★★
    @londongirl

    Hi Nuribeslen – Twinvir is a new drug, there are quite a few patients sharing their treatment experiences on this forum now, although sometimes not in the same place so will involve some reading.
    I believe the Redemption Trials have been set up for this reason and will provide more detailed answers hopefully.
    I guess you can’t get the results without waiting for patients to finish their treatments.

    GT1a Dec14 F2/8.7 VL 900000-2.5M
    Jan16 Hepcivir-L MonkMed/Redemption
    Baseline: VL 913575 Alt 76 Platelets low
    Wk2 VL1157 Alt 23
    DET Wk 8 VL 32 Alt19 ‘In the slow lane’
    June16 Fibro 5.7 F0/1 LIF 1.5
    Wk 11 VL<12 Alt 13 Det/Unq
    Extending tx 12 wks Mylan Sofo/Dac MonkMed
    Wk 14 VL <12 Det/Unq
    Wk 16 VL UNDETECTED
    Wk 22 + 4 Wks Sunprevir FixHepC
    Wk 24 UNDETECTED Alt 13
    Wk 12 post tx SVR12 Wk 26 SVR24
    Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC

    12 November 2015 at 1:50 pm #3736
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    Twinvir works very well for the Genotypes mentioned above. There are many on other forums who have confirmed this.

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

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