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  • 12 November 2015 at 12:29 pm #3727
    nuribeslen
    • Topics: 2
    • Replies: 1
    • Total: 3
    • Novice
    • ★
    @nuribeslen

    I want to use twinvir but there is not enough shared and experinced patient in this forum

    12 November 2015 at 12:37 pm #3728
    Avatar photoklhilde
    • Guardian Angel
    • ★★★★★
    @klhilde

    What genotype are you?

    Twinvir works well for types 1a, 1b, 2 and 4 … not quite so good with type 3.
    Twinvir is from Incepta from Bangladesh.
    Incepta also has Hopetavir (sofosbuvir), and the new Virodacla (daclatisvir)
    The sof/dac combo is better for type 3 and works very well across all genotypes.

    12 November 2015 at 12:40 pm #3729
    Avatar photoLondonGirl
    • Guardian Angel
    • ★★★★★
    @londongirl

    Hi Nuribeslen – Twinvir is a new drug, there are quite a few patients sharing their treatment experiences on this forum now, although sometimes not in the same place so will involve some reading.
    I believe the Redemption Trials have been set up for this reason and will provide more detailed answers hopefully.
    I guess you can’t get the results without waiting for patients to finish their treatments.

    GT1a Dec14 F2/8.7 VL 900000-2.5M
    Jan16 Hepcivir-L MonkMed/Redemption
    Baseline: VL 913575 Alt 76 Platelets low
    Wk2 VL1157 Alt 23
    DET Wk 8 VL 32 Alt19 ‘In the slow lane’
    June16 Fibro 5.7 F0/1 LIF 1.5
    Wk 11 VL<12 Alt 13 Det/Unq
    Extending tx 12 wks Mylan Sofo/Dac MonkMed
    Wk 14 VL <12 Det/Unq
    Wk 16 VL UNDETECTED
    Wk 22 + 4 Wks Sunprevir FixHepC
    Wk 24 UNDETECTED Alt 13
    Wk 12 post tx SVR12 Wk 26 SVR24
    Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC

    12 November 2015 at 1:50 pm #3736
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    Twinvir works very well for the Genotypes mentioned above. There are many on other forums who have confirmed this.

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

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