Wednesday, 10 June 2015 06:40

Sofosbuvir Ledipasvir NMR and Mass Spec

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We were quite excited to see the first shipment of Chinese sourced Sofosbuvir and Ledipasvir. A white powder and and off white powder, but what would the NMR show? Here's the NMR for Sofosbuvir which is right on the money.

Ledipasvir: mass [M+H] + 889.4195 ( < 2 ppm error)

  • molecular formula - C49H54F2N8O6

Sofosbuvir: mass [M+H] + 530.1699 ( < 0.2 ppm error)

  • molecular formula - C22H29FN3O9P
Read 104952 times Last modified on Sunday, 30 August 2015 01:00

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