emo Need advise for gt4 treatment

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3 years 10 months ago #26994

Hello kaju,

Is it hot and humid where you exercise?


YMMV
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3 years 10 months ago #26995

I do in my home, and not much hot and humid. Normal.
I do since 1 month maybe and outside is 30-35 degree.
But sure I sweaty during exercise.


The thing is for my last 2 hcv rna test day.
I did not do any exercise before test.
I was at the exhibition and 5 days I used many steps ( Everyday overally 20.000 step during show and looking around the city ) and I stand at the booth all day.I did get not enough food I was tired end of the trip and was cold because of weather.

Before last test day I was at the trip for 3 days and I used alcohol and drink to much coffee. I feel little tired because of holiday you know, because of walk to much almost 20.000 step, I swam . Maybe dont drink good enough water because My glucose value was little high too. It was the first time . I dont used sugar since long tıme and all glucose value are ok just 1 month ago .

Last Edit: 3 years 10 months ago by kaju.
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3 years 10 months ago #26997

Hello kaju,

20,000 steps is a lot. Particularly where is it hot and humid, but also with people exercising without enough water intake we see these enzyme rises due to mild muscle damage.

So please make sure you get enough water when exercising. For most people getting enough water means you need to urinate several times a day and that urine is ~ 1/2 way between clear water color and dark urine colour - too much water and it becomes very pale, not enough water and it becomes very dark.


YMMV
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3 years 10 months ago #26999

Thank you for your advise. When I think about it now, I realized I havent drunk enough water especially before test days.

One time , I lay on my back and I hold my legs with the bend knees position. Hope I explained correctly. Because english is not my first language.


I hold them 2 minutes , because I readed in paper, healty people can do that for 2 minute. I did, but my abdominal muscles worked and contractioned. Sure i did not do before warm up exrcise .Other day I got test and ck enzyme increased to 2000 . After 2 day rest at the weekend and drunk much water ıt deacresed to 400 from 2000. I havent checked following days again.

I will do test after drink too much water and stable 10 days before next hcv rna test for next month.
Hope will be still undedected with normal enzymes.
Thank you very much again for your help and reply all my obsession questions. One of my doctor told me I should see psychiatrist because I am very worried guy . Hope I am because if she rights thats mean I am healty :)
Best Regards
Cheers.

Last Edit: 3 years 10 months ago by kaju.
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3 years 10 months ago #27001

Hello kaju,

Being worried during Hep C treatment is not a reason to see a psychiatrist. It is completely normal!

It does sound like you are pushing the exercise a little too hard, a little too fast.


YMMV
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3 years 8 months ago #27176

Hi Guys,
Today I got my new alt result. Still waiting for hcv rna pcr ı thinh in few days I will get it.


My previous results 31.07.2018: AST 99 ALT 100 viral load : undedected SVR4
Refresh results 20.09.2018 : AST:48 ALT: 46

I do dumble exrcies at home and 10 day before test day, I gave break.

Can we say all is good or should I wait for viral load result to see what is really happening …!
Cheers.

Last Edit: 3 years 8 months ago by kaju.
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3 years 8 months ago #27177

Hello Kaju,

We have seen your AST and ALT elevated from what sounded like too much exercise. Obviously, your numbers are lower (always good). If they were 20 I would be positive the RNA would come back negative. I expect it will be fine, but you (like me) will have to wait to see the RNA to be 100% positive.


YMMV
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3 years 8 months ago #27180

I want to be positive for undedected.
If I look the past, alt and ast was more higher but get undedected at eot and svr4 . Now they more less and maths must be work . Hope so ..
God knows and pray for this .

Thank you for your reply ..Regards..

Last Edit: 3 years 8 months ago by kaju.
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3 years 8 months ago #27182

Hi Guys,

I just received my hcv rna result and it s undedected !!

HCV-RNA (real time PCR) : viral genom not dedected
dinamic range of test:12 - 10-8 IU/mL


Thanks God and thank you for all your replys to my questions and
especially thank you very much Dr James.

I am at the SVR12 now and I hope will reach to SVR 24 .
Cheers

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3 years 8 months ago #27183

That is awesome Kaju, things are looking great :cheer: . Looking forward to your cure announcement after the SVR24 test :+1:

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3 years 8 months ago #27184

Such great news! Looking forward to your SVR24 results.


G4
F0-F1
diagnosed in 2006
Tx naive
Treatment started 8/12/16, Ledipasvir/ Sofosbuvir (Harvoni) supplied by Monkmed
8/1/16 ALT 36 AST 40
1/4/17 ALT 17 AST 21
7/13/17 ALT 17 AST 25
12/28/17 ALT 22 AST26
2/22/18 ALT 19 AST 25
7/10/18 ALT 26 AST 32
1/8/19 ALT 16 AST 28
7/2/19 ALT 16 AST 26
Hcv Rna, Quantitative Real Time Pcr <15 NOT DETECTED (IU/mL) NOT DETECTED
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3 years 8 months ago #27185

It must be time for the dancing banana!

#magic


YMMV
Last Edit: 3 years 8 months ago by DrJames.
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3 years 8 months ago #27186

Thank you again. I feel more happy now :) :cheer: Todal will make little party for this with refresh foods and healty drinks :)
Hope I will come here with good news again after 3 months.


Cheers

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3 years 8 months ago #27187

Congrats on your SVR 12 kaju!

Look forward to reading about your SVR 24
Enjoy!

S


Diagnosed: 2001 GT1a , HCV since mid-70's.
Biopsy 2010 F1
Fibroscan and Fibrosure 2018 F2

Treated in trial 2010 with Dac/Peg/ Riba and Relapsed.

Resistance test 2017. Have Ns5a Rav Q30r/H58d enhanced from doing Dac.

Start Tx. Jan 18th/18 w/ Vosevi /Riba 12wks. plus 6 wks.Viekira Pak +Sof/Riba(From Dr Freeman @GP2U)

VL start: 1.6mill.ALT 125 AST 88
Wk. 4 Det @LLOQ <15.
VL Wk.8 UND Alt &Ast 22
Wk. 12 UND
EOT:UND

EOT+12 >>>UND (SVR12)! ALT11 AST13
Nov6/18 SVR 24!
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3 years 8 months ago #27191

Congratulations kaju!! Enjoy your party :woohoo:


G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!)
Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back!
New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217.
SVR12 and SVR 24...
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