TOPIC:

I was on 8 weeks of Mavyret and due to Covid could not get labs done in the middle of treatment. One week AFTER treatment I was finally able to get my viral load test done and was still detected but below level of quantitation. Basically a viral load of less than 12, but still detected.

Fast forward to today, I just received the EXACT same result and it has been 12 weeks since my last dose of Mavyret.

My viral load didn’t rebound or relapse, but here I am... still testing detected 12 weeks post treatment.

I just don’t understand it. My liver labs are perfect. All labs are great otherwise.

Hello joy2world,

Please don't worry. If you were going to relapse you would have by now.

I would be confident that a PCR at 24 weeks will come back negative.

The tests have got a lot more sensitive over the years and detect down to very tiny residual traces.

Thank you so much. I’ve been thinking the same thing, but my mind has been playing tricks on me.

My treatment was only 8 weeks long, but I’ve read people on much longer treatment courses still detecting at the end of treatment. But I’ve never seen anyone test detected at 12 weeks post treatment, so I freaked out initially.

But then I’ve read many people testing detected on the Abbott and undetected on the other less sensitive test. Also, on the Mavyret website it states their cure rate as SVR12 as anything <LLOQ 12 weeks post treatment and they didn’t use the LLOD in their clinical trials. I found that pretty interesting.

I appreciate the response! Makes me feel a little less apprehensive about the whole situation.

Update-

GI doc was puzzled with the <LLOQ target detected results and consulted with their Hepatologist.

She wasn’t at all concerned (thankfully) and advised her to recheck my labs again in 3 months. Apparently, she has seen this happen in her patients before and it isn’t a cause for concern since I haven’t had any sort of viral relapse in 12 weeks.

Fingers crossed for an SVR 24. The wait continues!

Hi joy2world,

Even though everything indicates a good outcome it is difficult not to be a bit worried when waiting for test results. We'll have our fingers crossed with you for your SVR 24. Hang in there.....

Hello joy2world
I will say one thing and you can look at my entire record I recorded here, mine said almost the same thing until it didn’t. I was
Indeed 100% cured and yes it took a little time to post. You have got this! Please do not waste a moment of your precious life considering anything but.
May God be with you.
Sven

I AM CURED AT LAST!!!! Took until the 24th week post treatment to finally receive NOT DETECTED.

Thank you all so much for the kind words of encouragement. I hope I can bring hope to those who tested DETECTED 12 weeks AFTER treatment. There is still hope that you will indeed go on to clear!!!!

Congratulations joy2world,

Now, it's just got to be time for a happy dance



Best wishes

James

I knew you had this! Like the rest of us whom have been cured, PLEASE enjoy your new long life......you’ve earned it.
May your God walk with you always.
Sven

Hi Sven,

Thanks for the reassuring words from somebody who has walked in those shoes!

Best Regards

James

Thank you all so much. I can’t even begin to describe how thankful I am for all of you. Without you, I would have fallen into a very dark place.

A year ago today I found out for certain that I was carrying around Hep C for over a decade with my very first RNA test results. One full year from start to finish, and it’s been one hell of a rollercoaster ride. From my treatment beginning and ending right at the height of the Covid-19 pandemic and not knowing for sure if treatment was working, as I was not allowed to have labs done during treatment due to Covid. To not clearing at a week after EOT, to not clearing 12 weeks after EOT, to finally clearing 24 weeks after EOT. Whew! What a wild ride it’s been!

2020 has been a shit show for so many, but I will always remember it as the year that I took the step to get my life back on track. I’ll forever be grateful to you wonderful people for always offering kind words of encouragement and wisdom!

Thank you, thank you, thank you! May you all have a blessed holiday season!

Hi everyone its been a long long time since I have been here but still keeping an eye on everyone. Joy2world what wonderful news! You must be feeling so good at the moment despite all the other crap going on. It is such a joy to know this programme continues to help people get well.

As I have said before and will carrying on saying Dr James you are a star!!!! Thank you.

Joy2world lets hope other things will improve in all our lives and allow you to enjoy the full extent of recovery.

Take care of yourselves everyone.
much love and hugs (oh those illusive hugs!!!)
Nads

Hi Nads,

Thsnks for the kind words. Like joy2world says 2020 has been such a shit show - it's nice to be able to share a little bit of happiness!

Best Wishes

James

So, I was wondering... is this the song?

Haha yes!!! One of my all time favorites!