Fitz starts REDEMPTION 3 Trial

This topic has 306 replies, 32 voices, and was last updated 7 years, 10 months ago by fitz.

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5 September 2016 at 8:27 am #22793
Sven
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- Guardian Angel
@sven
Hey brother, I know your cured so please make plans to enjoy your life. We all here appreciate your wisdom as it is obvious you’re extremely gifted and you have so much empathy and praise for those whom have had a hard time dealing with what HCV has done to them and their family
May our paths cross again my friend as the world is a small place and may God be with you always.

Contracted HCV 1980’s
Geno Type 1a
F3 ( doc says once treated I’ll be F2 maybe F1)
Meds shipped 6/17/2016 arrived early 7/2016

Viral count – 3,471,080

4 week quantitative bloods: August 17, 2016. I have been diagnosed as <15 (told undetected)

8 week quantitative bloods: September 14th. I have been diagnosed as <15 (told undetected)

11 week PCR RNA Qualitative bloods: September 26th 2016 – Undetected

December 19th 2016: Cured!
Viral count: zero!!!
2018 viral count: still zero!
Cured!
6 September 2016 at 3:54 am #22813
fitz
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- Guardian Angel
@fitz
Thanks my friend. We’re all in this together, for and with each other. Just sent a Karma point your way brother! Would give you ten if I could!
6 September 2016 at 4:06 am #22814
beaches
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- Guardian Angel
@beaches
You got this bro, I can feel it in my waters

Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
6 September 2016 at 7:17 pm #22821
fitz
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- Guardian Angel
@fitz
Thanks Beaches! Still have that Champagne locked and loaded for you, and for Meg too! Have decided to wait until EOT +4 weeks to test again. The way it works here, EOT VL is on the test schedule, as is SVR12, but nothing in between. So will use the EOT tests at 4 weeks post EOT, to determine if SVR4 has been reached.

If I remain UND at SVR4, then we can infer UND at EOT as well. My decision, my consequences, but hey – I bucked the system to get here, and reaped the rewards with <15 at 6 weeks, and UND at 8 weeks. I think I'm starting to get the hang of this

May pop into a walk in testing facility for interim LFTs. If so will post.
6 September 2016 at 9:07 pm #22822
isaing4
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- Total: 239
- Guardian Angel
@isaing4
fitz wrote:

Yesterday was my last dose of generic Sof/Led obtained through the REDEMPTION 3 Trial. 6 weeks since VL <15, and 4 weeks since UND.

Today is EOT for me, and it feels a bit surreal not to have opened the bottle of MYHEP LIVR -- Generic 'Harvoni' Sofosbuvir 400mg, Ledispavir 90mg produced under Gilead license in India by Natco for Mylan. The medicine bottles are now quite empty, there is no medicine left. I have taken the entire 12 week course of treatment. I'm done.

Happy EOT and only UND!

HCV since I don’t know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive,
started 12 wks Twinvir on 06.12.2015. Feeling great and grateful 🙂
virus not detected 06.02.2016 & SVR24
isaing4@gmail.com
7 September 2016 at 1:09 am #22826
Ariel
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- Guardian Angel
@ariel
Wishing you all the best Fitz
Sounds great for SVR4 coming up and like you say LFTs are a fallback when we need a little boost I sure use that blood test often enough since SVR12 even! (Just being vigilant)
I’m backing you Fitz your empathy and kindness are so appreciated too on this forum by myself anyway! You are always so encouraging and affirming
Sending you Goodvibes for your forthcoming path
Happies from Ariel
7 September 2016 at 6:46 am #22831
beaches
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@beaches
All I got was EOT and 12 weeks, that will do me, but will ask my GP (General Practitioner for you S….. sorry, Americans) for LFTs in a year or so.

Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
7 September 2016 at 6:47 am #22833
fitz
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- Total: 499
- Guardian Angel
@fitz
We get by with a little (or a lot) of help from our friends! OK Karma party! Thank you for your well wishes Ariel and Isaing! Pow, pow! Everytime I log on – good karma points are going out!

Yeah baby!
7 September 2016 at 6:56 am #22834
fitz
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- Total: 499
- Guardian Angel
@fitz
beaches wrote:

All I got was EOT and 12 weeks, that will do me, but will ask my GP (General Practitioner for you S….. sorry, Americans) for LFTs in a year or so.

Ha Beaches – you stinker you! I knew you couldn’t resist…. Breath deeply dear. Yoga breaths – that’s right!
7 September 2016 at 7:26 am #22837
beaches
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- Total: 760
- Guardian Angel
@beaches
Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
24 September 2016 at 1:30 am #23239
Matt-Kenney-google
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- Total: 424
- Guardian Angel
@matt-kenney-google
Just caught up to the last exchange between you 2, (fitz & beaches) …. couldn’t resist m’self …. YOU GUYS are toooo fun …. Thanks for being that way
Matt

GT1a; Got it some time in the 70’s; Diagnosed @1976
Tx naive
METAVIR: A2-F2
SOT May 18, 2016: CMP: AST 162 ALT 241 VL 13000000
3 weeks after SOT: AST 27 ALT 31 VL 138
Reached EOT Aug. 10, 2016 / Received svr4 results Sept. 20, 2016: AST 22 ALT 24
Hep C RNA NOT DETECTED”
24 September 2016 at 4:52 am #23243
beaches
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- Guardian Angel
@beaches
Hey Matt and Fitz, here’s something that will help you connect with your inner selves

https://www.youtube.com/watch?v=VDLzl-Ozg1A

Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
24 September 2016 at 9:33 am #23244
Sven
- Topics: 6
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- Total: 333
- Guardian Angel
@sven
Keep on rolling my man, you deserve all this! UND, frign beautiful, just beautiful.
In good health to you

Contracted HCV 1980’s
Geno Type 1a
F3 ( doc says once treated I’ll be F2 maybe F1)
Meds shipped 6/17/2016 arrived early 7/2016

Viral count – 3,471,080

4 week quantitative bloods: August 17, 2016. I have been diagnosed as <15 (told undetected)

8 week quantitative bloods: September 14th. I have been diagnosed as <15 (told undetected)

11 week PCR RNA Qualitative bloods: September 26th 2016 – Undetected

December 19th 2016: Cured!
Viral count: zero!!!
2018 viral count: still zero!
Cured!
24 September 2016 at 1:30 pm #23259
LondonGirl
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- Guardian Angel
@londongirl
Hey, Good idea Fitz (re VL testing).

I hope there’s a glass of fizz chilling for me too?

All my best wishes go with you

Cheers

GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
27 September 2016 at 3:07 am #23288
fitz
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- Total: 499
- Guardian Angel
@fitz
Hey ya’ll, RHF, Ariel, Matt, Beaches, LG, and Sven, I appreciate the well wishes!

Went in for EOT +4 week labs before the sun was up, and had CMP and CBC results back before noon.

Good news so far. LFTs are in the normal range as are all other metabolic markers. Blood counts are completely normal for the first time in memory. Will have VL tests back in a few days.

Fingers crossed my friends!
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