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14 December 2015 at 8:23 pm #6271
Just out
Treatment naive
F 3/4
Genotype 1 a & b
V/L 17 MILLION
Started Harvoni 11th Dec 2015 for 12 weeks
4 weeks VL UND
6 WEEKS ALT 32, AST 34
EOT 03/03 2016 ! UND
ALT 34, AST 26
04.04.2016 SVR 4
26.05.2016 SVR 12
16.08.2016 SVR 2414 December 2015 at 11:01 pm #6283Great – So now just Cipla then?
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC14 December 2015 at 11:13 pm #6284yes but they have released an anti aging product if you like that. Lol
http://www.cipla.com/uploads/mediakit/1449134151_Cipla-launch-Cutisera.pdfThere is one more Pharma Zydus Cadila to release Harvoni soon
Treatment naive
F 3/4
Genotype 1 a & b
V/L 17 MILLION
Started Harvoni 11th Dec 2015 for 12 weeks
4 weeks VL UND
6 WEEKS ALT 32, AST 34
EOT 03/03 2016 ! UND
ALT 34, AST 26
04.04.2016 SVR 4
26.05.2016 SVR 12
16.08.2016 SVR 2415 December 2015 at 12:20 am #6288yes but they have released an anti aging product if you like that.
I take ten bottles ha ha
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC15 December 2015 at 7:37 am #6325Mylan
http://www.mylan.in/en/Like the Cipla website, Mylan’s site is not set up for consumers/patients to find information about specific drugs or distribution channels. Stlll looking for trustworthy retail sources.
Mylan is the authorized reseller of Gilead’s Sovaldi brand (Sofosbuvir) and presumably soon also Harvoni (Sofosbuvir/Ledipasvir.)
Contractually they are limited to only allowing delivery of a single 28 tab bottle, with the next order given on return of your empty bottle.
Don’t play their game.
There is no reason whatsoever to believe that the Gilead branded product is in any way superior.
Available Generic Products:
MyHep (Sofosbuvir 400mg)
28 tab bottles
19 December 2015 at 4:35 pm #6721
Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured30 December 2015 at 12:26 am #7501When getting quotes from distributors in India I’ve found this one to be cheapest of three Harvoni generics, dunno why is that, hopefully it is not quality issue:
Genotype 1b & 4, F0/A1, failed Peg&Riba TX 2015,
22 Jan. 2016 – Back from Delhi with 12 week Ledifos supply 🙂 Thx to Parag
Started TX on 27.Jan.2016 – AST 41, ALT 59, GGT 39, ALP 74, VL 500.000, Fibroscan 6.8
19. Feb 2016 – ALT 14, AST 14, GGT 19, ALP 107
19. Apr 2016 EOT – Undetected 🙂
26. Apr 2016 (1 week after EOT) – ALT 14, AST 17, GGT 12, ALP 77
28. Aug 2016 (17 weeks after EOT) – UND, ALT 15, AST 12, GGT 5, ALP 39 🙂30 December 2015 at 12:31 am #7502Received an email today :
The rate per bottle of Hepcinat LP @ $380usd (28tabs per bottle) including shipping .
The rate per bottle of Myhep Lvir @ $360usd (28tabs per bottle) including shipping
The rate per bottle of Ledifos @ $350USD (28Tabs per bottle) including shipping.
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC30 December 2015 at 4:07 am #7513Geno1b4 wrote:When getting quotes from distributors in India I’ve found this one to be cheapest of three Harvoni generics, dunno why is that, hopefully it is not quality issue:
As it is also manufactured by Natco I would suspect (but obviously can’t confirm) it is coming off the same production line but with different packaging.
We need to remember that with such recent release (only a few weeks ago) the various manufacturers and distributors will be jostling for marketing advantage. Larger ones will have the advantage of volume to reduce prices but OTOH they will be better known and trusted so can charge a premium while smaller ones are the reverse. Then there will be “special introductory offers” to gain initial market share but if these result in the distributor risking running out of stock they will put their prices back up until they can restock. I suspect in six months or so the market will be more settled with “household name” brands charging a slight premium and the lesser known ones being slightly cheaper. This is marketing today!
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
30 December 2015 at 1:08 pm #7535I agree GAJ,
I have decided to go through Redemption.
This takes all the worry of supply chain integrity away – essential here in England to get NHS medical support onside (free). My GP was very peased to hear the word ‘Cipla’ !Also takes away the worry of the confusing bombardment of emails from various sources arriving in my email account! (some a little aggressive).
It is a little more expensive, but saves hundreds, possibly thousands in monitoring while on tx. (which I don’t have!)
It also offers Dr support, side-effect monitoring and advise from some lovely, polite and helpful Drs. via MonkMed & Dr F. / GP2U.
The fact the trial results will be taken to the ‘powers that be’ is also a bonus as it may contribute to helping others in the future, so this ‘gives something back’ in a small way.
Hopefully, this will be my one and only treatment, fingers crossed, so as I have carried this damn thing for many years, I’m not going to risk a purchase from someone I don’t fully trust, this should also lessen any anxiety during treatment.
So for a small extra cost that takes so much worry away, for me and gives peace of mind, it’s the only way to go !
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC30 December 2015 at 1:19 pm #7539Great to hear you’re on the way now LG! and on the trial (me too heh)
Completely agree about helping to provide data that will assist others and the docs to better guide and treat…the main reason I’ve hung onto my meds the last month. I’ve been given so much just by having the opportunity to access tx, feel its only right to be able to help if possible.
GT1a since 1988, diagnosed 1990
F0, tx naive
VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 – 2.9
Started Mesochem sof/dac 12 weeks 01/01/2016
11/02/2016 – 6 weeks UNDETECTED
AST 26
ALT 2630 December 2015 at 1:37 pm #7542Great to hear you’re on the way now LG! and on the trial (me too heh)
Thank-you Zhuk My very best wishes to you
I’ve been given so much just by having the opportunity to access tx, feel its only right to be able to help if possible.
Absolutely , especially to the new-comers diagnosed recently, there is so much to learn, as I have been over the past 18 months, the stress has been terrible, especially pre the good people like MonkMed, Dr F & Gregg J. I was looking at the old triple with Telap / BOC (shudder) & possibly loss of job & home,
If I can be of any help in any small way I will, but collectively, we may be able to help ‘move mountains’
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC30 December 2015 at 2:07 pm #7544LondonGirl wrote:have decided to go through Redemption.
This takes all the worry of supply chain integrity awayHave to agree LondonGirl,
The Doc’s organising of the Redemption trials must give huge confidence to both heppers and doctors who were concerned about generics both from a sourcing and quality point of view. This was a big factor in my decision to use the FixHepC buyers club when I stumbled onto the generics path three months ago. Set up by a well known Australian doctor with easily checkable veracity (yep, I did due diligence ;~} ) who was happy to front our national media and had set up a system of NATA level testing for each import we made was a huge confidence booster for me. But of course only available for Australian delivery unlike Redemption .
I must admit I would have liked to participate in these trials myself but it was early days then and my priority was to get treatment started asap based on my state of health. I can be very impatient when I decide a course of action.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
30 December 2015 at 2:17 pm #7547I hear ya GAJ,
I decided to wait, mainly due to monitoring issues here in the UK & life responsibilities. In a different senario I may well have taken your path, after all, it is ultimately our own responsibility to make an informed choice and take control of our health where possible. We do what we have to do.
However, waiting for NHS support (still waiting for consultant re-referral as I type) and the release of better-known generic meds for that reason, was important to me, didn’t want to ‘go it alone’.
The fact it may help others in a small way is definitely a bonus though
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC30 December 2015 at 3:38 pm #7558Hi Gaj,
Re: Redemption trials
“I must admit I would have liked to participate in these trials myself but it was early days then and my priority was to get treatment started asap based on my state of health. I can be very impatient when I decide a course of action.”
I did wonder whether there is any way of contributing our data to this trials? I expect though that doing this in such an ad hoc manner would be a big no no.
J.
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