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  • 19 March 2016 at 8:28 am in reply to: labs and their techniques? #14164
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    As in my case <25 and a note UNDETECTED at the LLOQ.
    Abbot test is <15 LLOQ
    Roche Cobas Taqman <25 LLOQ
    AND if its detected it will mention as detected but sometimes the guy who writes the report forgets to write UNDETECTED <15, <25 <...... SO DONT PANIC

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    18 March 2016 at 11:05 pm in reply to: labs and their techniques? #14133
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    Where I live its state provided and they use the TaqMan COBAS which <25 as LLOQ
    The link is provided above by LG
    Features
    CE-IVD: Sensitivity (LOD; genotype 1) – plasma: 9.3 HCV RNA IU/mL, serum: 8.8 HCV RNA IU/mL; linear range – 25 to 3.91×10^8 IU/mL
    FDA-IVD: Sensitivity (LoD; across all genotypes) – 20 IU/mL; Linear range –Quantitation of HCV RNA from 25 to 3×10^8 IU/mL
    COBAS® TaqMan® 48 Analyzer for automated real-time PCR amplification and detection

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    18 March 2016 at 3:33 pm in reply to: EOT Viral Load result #14119
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    Just got mine and its UND at EOT of 12 weeks.

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    18 March 2016 at 3:07 pm in reply to: EOT Viral Load result #14116
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    https://www.hepmag.com/blog/new-hepatitis-c-trea-2-1

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    18 March 2016 at 2:23 pm in reply to: HCV RNA UNDETECTED #14114
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    http://hepatitiscnewdrugresearch.com/hcv-viral-load-test.html

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    18 March 2016 at 1:53 pm in reply to: HCV RNA UNDETECTED #14111
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    Just to add to this thread at 4 weeks into treatment my V/L was <25 and it clearly mentioned on the report as VIRAL LOAD IS BELOW LLOQ NO HCV-RNA detected. I am on Harvoni from Gilead. I consider this as undetected so does the doctor.
    So I guess it depends on the test. Now waiting for the EOT V/L results.
    Personally I would consider <12 as undetected maybe the lab guy forgot to mention UND.
    But as we all know SVR 12 AND 24 is all that matters so be it <12 or <25 its a great result which shows the medicine has CLEARLY worked or working.

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    18 March 2016 at 1:20 pm in reply to: EOT Viral Load result #14107
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    Great to hear this !

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    14 March 2016 at 10:59 pm in reply to: Any Post-Treatment Reflections? #13814
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    feeling ok here been 11 days off tx. Some edema ankle remains. Put on 6 kgs on tx, still eating like a glutton :P

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    14 March 2016 at 12:19 pm in reply to: HARVONI FATIGUE #13801
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    For ME it was the first 8 weeks where I was really tired. Finished tx seems ok now.

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    10 March 2016 at 1:09 am in reply to: EOT today! #13588
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    Best of Luck !

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    8 March 2016 at 10:50 am in reply to: Lynne’s SVR4 results are in!! #13513
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    using COBAS TaqMan HCV test, v 2.0 the detection range is <15 to 100 million yours is below 15 so not possible to detect lower than this ONWARD TO SVR 12. Congrats

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    7 March 2016 at 3:23 pm in reply to: HCV Viral Load and Speed of Decline Do Not Predict Cure #13469
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    http://forums.hepmag.com/
    Many many stories like this there

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    6 March 2016 at 3:08 pm in reply to: BP while on Tx #13429
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara
    darbara wrote:

    mine was 140/80 but on Harvoni it shot up to 186/95, 180/80 etc. so it does make the BP higher but NOT in all cases.
    Its now at around 150/85. I do take BP meds for long before DAA treatment

    EOT back to 140/80 or lower

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    5 March 2016 at 12:33 pm in reply to: Official FOI FDA Side Effect Reports #13361
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    Edema

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    5 March 2016 at 10:35 am in reply to: HCV Viral Load and Speed of Decline Do Not Predict Cure #13353
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara
    LondonGirl wrote:

    Hello Dr F, I have read much patient experience regarding this, have a friend on VPak detectable EOT and told he’d failed only to go on to clear at 3 months post tx – Interesting. Is there ‘any’ sort of pattern appearing?

    Yes if you see the US forums there are many examples of this kind of pattern where detected EOT and at 4 weeks EOT but got SVR 12

    Even for the doctors these are new drugs and their experiences are limited. The article is a year old but glad its here just reduces the anxiety and panic.

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

  • Author
    Posts
Viewing 15 posts - 31 through 45 (of 166 total)
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