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Hello Kansuke, your test results are quite encouraging, your liver fibrosis is low and Genotype 2 is one of the easiest genotypes to treat. Regarding the needed prescription, of course you know that the decision tool is just for general guidance and that the doctor is the one who will ultimately decide which medication is right for you. However, in terms of generic medications, if you take a look at the international treatment guidelines https://fixhepc.com/genotype-specific-hepc-treaments.html they indicate that treatment naive Genotype 2 patients with low fibrosis (such as yourself) should be treated for 12 weeks without Ribavirin with either one of the following medications (both of them are extremely effective with about 95% cure rates) :
1. Sofosbuvir 400 mg + Daclatasvir 60 mg (Sovaldi® + Daklinza®), which is REDEMPTION-2 on the FixHepC website https://fixhepc.com/redemption-etrials
2. Sofosbuvir 400 mg / Velpatasvir 100 mg (Epclusa®), which is REDEMPTION-4 on the FixHepC website https://fixhepc.com/redemption-etrials
Best of luck to you.
Making the world a better place – one patient at a time.
Hello Elizabeth, welcome to the forum. Just because the test gives an untedectable result, doesn’t mean that the patient is cured and should stop the medication. The virus can come back after an undetected result if the patient doesn’t continue treatment for the duration indicated in the prescription. Also, GT3 is the hardest to treat, your mum should continue her 24 weeks treatment especially that she was detected at 12 weeks. I know that Ribavirin is not the easiest drug to take, but it will be all worth it at the end. If she continues her 24 weeks treatment, there is an excellent chance she will be cured.
Making the world a better place – one patient at a time.
Great work Hazel, very very nice
Making the world a better place – one patient at a time.
Hello Tototo, extending treatment duration has been proven to increase cure rates in a large study conducted by the United States Department of Veterans Affairs. Please see this thread in which Dr James Freeman discusses its results https://fixhepc.com/support-forum/experts-corner/1576-8-weeks-versus-12-weeks-harvoni.html#24591 Hang in there, it will be over soon enough, and as Hazel said, drinking plenty of water helps most patients minimize or avoid side effects.
Making the world a better place – one patient at a time.
Hello Maga, welcome to the forum, and congratulations on starting your 84,000 USD treatment . Looking forward to your 4 weeks test result, there is a very good chance you will be undetected by then, most patients on DAA treatment are, best of luck.
Making the world a better place – one patient at a time.
Asta este o veste minunată Nelu, felicitări pentru tratamentul tău și pentru nivelul tău de Fibroză care coboară de la F3 la F1, e minunat
Making the world a better place – one patient at a time.
Congratulations Songbird, that’s fantastic news
Making the world a better place – one patient at a time.
Hello Paul, and welcome to the forum . The University of Liverpool in the UK has a dedicated page for checking interactions between the new Hepatitis C medications (DAAs) and other common medications, and when I checked the ‘Sofosbuvir + Daclatasvir’ combo and ‘Sildenafil’, the result was ‘No Interaction Expected’. You can take a look here https://www.hep-druginteractions.org/checker
Making the world a better place – one patient at a time.
Hello wrightjw198034, welcome to the forum, and congratulations on starting treatment . Don’t stress out, even though Genotype 3 is the most difficult of all genotypes, it’s still easy to treat for treatment naive patients with the new DAA medications, such as Epclusa. So if the generic Epclusa you’re taking is of good quality, your cure chances are really excellent with the standard 12 weeks course, about 90% (95% for the other genotypes).
Also, if you’re undetected at 4 weeks, it does not mean that you will be cured after the end of treatment with total certainty. Cure can be declared with 99% certainty when a patient has an undetectable test 12 weeks after end of treatment. The certainty increases to 99.9% when the test yields an undetectable result 24 weeks after end of treatment, this is the golden standard for declaring a patient cured.
On a side note, if you’re undetected at any time after start of treatment, there is no need to waste time and money by taking the test again until you finish treatment, because once you’re undetected during treatment, you will stay undetected until you finish it.
Making the world a better place – one patient at a time.
Hello 808cruiser, welcome to the forum! Strange as it may seem, your viral load has very little correlation to cure rate. Patients with high viral loads have the same excellent cure chances as anyone else, 95% for Genotypes 1,2,4,5,6 and 90% for Genotype 3, when treated with the modern direct-acting antiviral medications, or DAAs (e.g. Harvoni®, Epclusa®, etc). Besides, 4 million is not very high, I know FixHepC patients who started treatment with about 30 million viral load and got cured easily. It’s common to see a patient with a 16 million viral load go to 1,600 in the first week of treatment, these drugs are remarkably effective. Please this thread of the forum for more on this topic https://fixhepc.com/forum/fixhepc-admin/1930-viral-load.html#26786 Best of luck to you.
Making the world a better place – one patient at a time.
Welcome to the forum Bobraas . It has never been easier to get rid of Hep C as it is right now. With cure rates north of 90% with the new medications, and the availability of high quality generics (if insurance denies treatment), you made a great decision. As Hazel said, life for patients divides sharply into “before” and “after” because of how much better they feel after being cured, best of luck to you.
Making the world a better place – one patient at a time.
That’s a really inspiring story, congratulations on your achievement, and your cure EC2
Making the world a better place – one patient at a time.
Outstanding humanitarian work Dr James, many lives will greatly improve because of that box of medicines you donated. Hopefully all Hep C patients’ lives in Mauritius will improve with your assistance
Making the world a better place – one patient at a time.
Nice job Hazel, keep piling up the pressure
Making the world a better place – one patient at a time.
Hello Michael, and welcome to the forum. Sorry about your mom’s condition. I know that FixHepC will try to help patients secure authentic affordable medications for all diseases, not just Hep C. Baclofen seems easily available in India where they source their drugs, so email Jan (help@fixhepc.com) and I think she can help.
Making the world a better place – one patient at a time.
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