I know a few people here in Australia have have recently treated, some with Viekira Pak (Geno 1s) nd other with sofosbuvir and ribavirin (Geno 3s) all were cirrhotic with cricket scores for liver function ALT, AST and GGT and a range of other issues associated with the cirrhosis. It is amazing that all since SVR they have within normal range liver function. All are feeling the best they have in a long time and so I guess there will be an expectation that things will only improve from this point. It would be interesting to track some of this with research, perhaps it’s already been done to some degree? Em

Hi DT

I wasn’t commenting on scarring or fibrosis and I understand that the correlation between LF testing is no indication of fibrosis progression. I guess I was just providing insight into several friends have now are feeling much better and LF coming back to within range. A good news story I guess. Em

Sure valid point! But with my own experience on IFN/Riba for an extended period was that even when I cleared I was that messed up from the chemicals I couldn’t say that I had a sense of wellness, I was a bitter and twisted mess. And what I’m hearing from many people who are clearing now with DAAs they are feeling better than they had in a long long time. We don’t know what we don’t know hey? While this isn’t a scientifically validated fact, I am excited by the chance of feeling this way once again. See me there in my avatar, I want to get through that barrier, here’s hoping anyway. Sorry if this seems overly emotive and not backed by research. This isn’t a fairytale to those people, we have people on this site stating this and from other local forums. Lol dt love ya work oo Em

Accessing these medications might not be as simple as seeing a doctor, going to a pharmacy, and then getting them – but it is entirely possible.

Patients are doing it and the results look good. The absolute proof of SVR24 is not yet available but only because generics have only been available for 6 months. Our testing indicates that the generics are good copies so the only real reason they won’t demonstrate similar results is if the real active ingredient happened to be a small manufacturing by product contaminating the active.

This site, the forum, the chat part are just as much about social proof as they are about provisioning good quality information to people with a need to know.

A Google for

“dr james freeman” hepatitis c

https://www.google.com.au/#q=%22dr+james+freeman%22+hepatitis+c

Will turn up stuff dating back for the last 6 months.

Hi Stew,

Like you, I’m F4. I recently spoke with my specialist who told me that with the inflammation caused by HCV gone my cirrhosis was unlikely to worsen and would probably improve. He also mentioned that in some people the improvement can be remarkable. He did mention that my platelets steadily inproving back into the normal range was a positive sign for me as platelet count is linked to cellular repair.

While there is some suggestion that Silybum marianum (who thinks up these names? ) reduces inflammation and improves liver function there doesn’t appear to be much solid evidence regarding cirrhosis regression.

http://www.mayoclinic.org/drugs-supplements/milk-thistle/evidence/hrb-20059806

Hopefully, if SVR resolves my liver inflammation and improves its function anyway then I think I would prefer to let my body heal naturally for now in the area of cirrhosis regression. But with a watchful eye on the large amount of research that is happening in this field.

Hi logged after being away for a while… re this reversal of cirrhosis, I can report that I had it 18+ years. When I started Daa’s late 2015 it was urgent, with a Kp of 40. At end of treatment had halved to 22, still high but good result. At 24 weeks SVR, down to 9.5 so F2-3 which I had thought impossible. All tests done by same expert on modern machine on 12 hour empty stomach. I keep feeling better so I think when I go back again in a couple months will be lower still…… I didn’t know this was possible either, but it is.