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EOT- Relapse 8 years 2 weeks ago #13681

damn virus, sorry to hear your news Paul.
The thought is in my mind too....but these are fantastic drugs now and you will get rid of it.
good luck!
EOT UNDETECTED
Week 8 all bloods within normal limits
Week 4 Undetected
2016 - 28 January started Harvoni & Riba treatment
VL pretreatment 639,000 alt- 77
2015 fibroscan - 6.6
2 x non responder peg interferon & riba
geno 1a
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EOT- Relapse 8 years 1 week ago #14305

Really sorry to hear your news Paul. I reckon reducing high GI carbs and sugar is the way to go next time as others are saying. Wish I'd heard that advice before I started as I reckon high glucose levels are responsible for my slow response to Sof/Dac (I'm pre diabetic). I've relapsed so many times I'm finding it hard to stay positive about curing this time.

I know GT3 can be a bugger to cure but I reckon you'll do it next time. Just wondering why you are doing Sof/Dac again rather than waiting for some of the pan genotype drugs in the pipeline.

Anyway, big big hugs.
Marie
Geno 1a, HCV+ since 1981 35 years
3 previous attempts at curing, most recently with telaprevir in 2013.
f3/f4
Started 24 weeks of Sof/dac on 22/12/2015
2 week bloods ALT 12 AST 19
4 week vl 120 (aagh!)
8 week UND
EOT 7 June 2016 UND
1
SVR12 Undetectable! 6 Sep 2016
SVR24 Undetectable 23 Nov 2016 yippee!
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EOT- Relapse 8 years 1 week ago #14309

Marie,
The old drugs were like clubs and stones.
These new combinations are laser guided smart bombs.
You will nail it this go round!
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forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
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EOT- Relapse 8 years 1 week ago #14310

Hi Paul ,sorry to hear that news mate hopefully the next round will be the knock out punch you need to ko the little bastards
g3 since 96 :( 2 rounds of interferon in 2010 and again in 2012 and that was hell
4 week bloods <15
Undetected at 12 weeks :)
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EOT- Relapse 8 years 1 week ago #14311

Thanks for your encouragement. I see you reached SVR 12 recently. How fantastic. Congratulations!
Geno 1a, HCV+ since 1981 35 years
3 previous attempts at curing, most recently with telaprevir in 2013.
f3/f4
Started 24 weeks of Sof/dac on 22/12/2015
2 week bloods ALT 12 AST 19
4 week vl 120 (aagh!)
8 week UND
EOT 7 June 2016 UND
1
SVR12 Undetectable! 6 Sep 2016
SVR24 Undetectable 23 Nov 2016 yippee!
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EOT- Relapse 8 years 1 week ago #14319

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Hi Paul - I've been relocating for the past few weeks so am slowly catching up with the news. So sorry to hear yours but liking your attitude - it is what it is so lets get on with it.

Thanks all for the reminder about the carbs and glucose. I've taken less notice of this while I've been moving and things have crept back into my diet that probably aren't helping the fight.
G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!)
Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back!
New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217.
SVR12 and SVR 24
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EOT- Relapse 8 years 1 week ago #14380

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Thanks for the dood wishes guys and gals the Sof and Dac are Pan Genotypic Marie. We will see what the 4 week bloods look like by then there could be news from Barcelona regarding G3 tx options.

cheers
Two time relapser.

SVR 4 achieved 12/16 at last
SVR 12 achieved 22/02/2017 The Bastard has been defeated :):):)

GT 3 - about 28 yrs with HCV
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EOT- Relapse 8 years 1 week ago #14382

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Hi Paul,

Yes, if it was me I'd be trying the low GI diet as much as possible, it's not too hard & sugar cravings get less & less quickly when on that type of diet. Bet it'd make a difference.

Good luck my friend.

Remember I'm always a phone call away for you :)
x
J the young dragon slayer is:
HepC 1a since birth
Male aged 15
VL 2000000
Started Twinvir/ 10-11-15-then Sof/led.
NO sides so far !
after one week VL : 37
after 4 wks VL : UND !
EOT 2/2/16 UND.!
4 wks. post tx results....pending....
7/3/16 VL result : 4 week post tx: SVR !
12 weeks SVR !
24 wks SVR yeeaa!!

EOT- Relapse 8 years 1 week ago #14384

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Look forward to hearing the news from Barcelona also

we all keep goin :+1:

best wishes Paul
gt 1a VL 6m
F2/3 FibroScan - 9KPa in 2011 and 7KPa in 2015
sof/dac 10 December for 12 weeks
pre tx alt 85 ast 51
4 wk alt 34 ast 31 UND <35
8 wk alt 29 ast 32 UND <15
12wk alt 25 ast 25 EOT 3.3.16
SVR24 UND KPa5.3 F0 in normal range
I am well
.forever grateful to fixhepc
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EOT- Relapse 8 years 1 week ago #14391

#duck Paul, do you take R lipoic acid? I was taking it but stopped once I started treatment. I found it lowered my glucose levels (proven by blood tests) and I'm convinced it lowered my viral load as well. Might be an idea to take it in the months before starting treatment again to get the vl as low as possible. Do you know if it's OK to take while on treatment? I miss its glucose lowering effects.
Geno 1a, HCV+ since 1981 35 years
3 previous attempts at curing, most recently with telaprevir in 2013.
f3/f4
Started 24 weeks of Sof/dac on 22/12/2015
2 week bloods ALT 12 AST 19
4 week vl 120 (aagh!)
8 week UND
EOT 7 June 2016 UND
1
SVR12 Undetectable! 6 Sep 2016
SVR24 Undetectable 23 Nov 2016 yippee!
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EOT- Relapse 8 years 6 days ago #14418

Hi all, I used to take Alpha Lipoic Acid pre tx and stopped on tx as there was no guidance. I am wondering if that was the right thing to do too should anyone know.
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 'In the slow lane'
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
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EOT- Relapse 7 years 8 months ago #20036

That was supposed to be a PM to Archer, but it seems I'm struggling operating on this forum. Also wondering if Paul is an old Nomad refugee like myself. Weather he is or isn't, the 'R' word is a lousy outcome to have to grapple with.
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EOT- Relapse 7 years 8 months ago #20045

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Hi Skank,

I've removed your other post from public view and forwarded it to Archer as a Private Message. You can also send PMs on this site by clicking on the little blue speech bubble at the bottom of the side panel with their user name and other details to the left of a member's post. You can read PMs sent to you by clicking on your own name to go to your profile where you will find the link in a similar spot. Or via the link just under "Glossary" in the row of tabs at the top right of each page. (If that isn't showing click on the little blue tab to the right of the "Glossary" one.) Hope that helps.
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:
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EOT- Relapse 7 years 8 months ago #20046

Many thanks for that Gaj. I used to be quite active on several forums in the past, but my cognitive powers ain't what they used to be. Sure I''ll get the hang of it again eventually, and hope to participate a bit more around here when I do.
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EOT- Relapse 7 years 8 months ago #20167

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Alpha Lipoic Acid: I did too, please let me know ASAP if we can or cant during treatment.
Thx
Contracted HCV 1980's
Geno Type 1a
F3 ( doc says once treated I'll be F2 maybe F1)
Meds shipped 6/17/2016 arrived early 7/2016

Viral count - 3,471,080

4 week quantitative bloods: August 17, 2016. I have been diagnosed as <15 (told undetected)

8 week quantitative bloods: September 14th. I have been diagnosed as <15 (told undetected)

11 week PCR RNA Qualitative bloods: September 26th 2016 - Undetected

December 19th 2016: Cured!
Viral count: zero!!!
2018 viral count: still zero!
Cured!
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