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TOPIC: Two weeks Twinvir Undetected

Two weeks Twinvir Undetected 6 years 4 months ago #6931

  • IRMA88
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Great news Enkel, congrats :)
G2B - DIAGNOSED 2014, STARTED SOF/DAC 11/11/15 VL 6M
UND @ WEEK4
FINISHED TREATMENT 26/4/16
UND @ WEEK 24
ALT 12 AST 15
MY ETERNAL GRATITUDE TO GREG JEFFERYS & DR FREEMAN
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Two weeks Twinvir Undetected 6 years 4 months ago #6951

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The best news. Congratulations Enkel :cheer:
G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!)
Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back!
New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217.
SVR12 and SVR 24...
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Two weeks Twinvir Undetected 6 years 4 months ago #6963

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Great news Enkel another UND for the books. B)
Two time relapser.

SVR 4 achieved 12/16 at last
SVR 12 achieved 22/02/2017 The Bastard has been defeated :):):)

GT 3 - about 28 yrs with HCV
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Two weeks Twinvir Undetected 6 years 4 months ago #6966

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Awesome news, Enkel! - congrats :)
GT1a since 1988, diagnosed 1990
F0, tx naive
VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 - 2.9
Started Mesochem sof/dac 12 weeks 01/01/2016
11/02/2016 - 6 weeks UNDETECTED
AST 26
ALT 26
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Two weeks Twinvir Undetected 6 years 4 months ago #6967

I'm so happy for you Enkel....congratulations!! :)
Lives in Bendigo, Victoria
No prior treatment Genotype 1b Fibroscan 0 (only showed a bit of a fatty liver) Diagnosed in February 2015 Currently on my last week of treatment taking led/sof Last LFT normal
Insomnia the only side effect
Undetected at 4 weeks
SVR4 - undetected - all bloods good and GP very happy
SVR12 bloods to be done at end of April 2016
SVR12 - undetected!!!
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Two weeks Twinvir Undetected 6 years 4 months ago #6972

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Congratz Enkel
Mahbubul Hasan Leon
Senior executive,
International marketing,
Marketing Strategy Department,
Incepta pharma Ltd.
Phone: +8801715922964 (viber and WhatsApp )
Mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
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fixhepc.com/forum/daa-access/435-incepta-pharmaceuticals-sof-da
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Two weeks Twinvir Undetected 6 years 4 months ago #6975

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Fantastic Enkel!! So happy for you!
3a F0 TX Naive
Started Tx 12/12/2015 Kingswood Sof/Dac

Pre Tx - ALT 71 AST 40 V/L 9 million
Day 11 - ALT 12 AST 15
4 week - LFTs normal - detected (same sample sent for v/l showed undetected) :/
6 week - UND
12 week EOT - UND
SVR4
SVR12
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Two weeks Twinvir Undetected 6 years 4 months ago #6980

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GREAT news Enkel - so how are you feeling??
NSW Australia. Genotype 1b 30+ years, F0-F1, VL 91,000 Feb 2015 (740,000 in 2010), Tx naive.
Ordered Sof/Dac from Buyers Club 21 Sept, received 14 Oct.
Virus UNDETECTED at 3 weeks AND 12 weeks (EOT) AND SVR4 AND SVR12 AND SVR24. :-)
A thousand thankyous to Dr James and the amazing FixHepC team.
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Two weeks Twinvir Undetected 6 years 4 months ago #6987

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Welcome aboard Leon!!!
Mike
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G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
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Two weeks Twinvir Undetected 6 years 4 months ago #7001

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ENKEL!!! GREAT!!! So, how are you feeling now???
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Two weeks Twinvir Undetected 6 years 3 months ago #10595

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PCR test results came back. I worked HCV RNA quantitative test 22 days of therapy, and writes only NEGATIVE :woohoo: .
I expected that says "<15 IU / ml" or "<15 IU / ml" or UNDETECTED but writes only NEGATIVE.
Can HCV RNA quantitative test that is negative or only UNDETECTED, or should we say for example. "<15 IU / ml of"?
G1 F1 or F4 (I am not sure) 6. jan. 2014. -> Biopsy -> F1
24. dec. 2015 -> Fibroscan 16.3 kPa -> indicate chirosis
15. Jan. 2016 -> Fibroscan 10.2 kPa -> F3/F4
VL 30.000.000 - may 2015
VL 3.300.000 - dec 2015
Started TWINVIR treatment naive on January 13, 2016.
VL after 21 day UNDETECTED
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Two weeks Twinvir Undetected 6 years 3 months ago #10602

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The test should have a note about the LLOD or Lowest Level of Detection and LLOQ Lowest Level of Quantification. What are their values?

For cobas taqman LLOQ = 15

Negative is the same as Undetected.
Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured
Last Edit: 6 years 3 months ago by Enkel.
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Two weeks Twinvir Undetected 6 years 3 months ago #10604

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Yes, NEGATIVE is the word everyone wants to see!!!
M
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G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
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