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27 February 2016 at 8:07 am #12793
Hi
Hello everyone, I’m new to this site. I’ve noticed there have been posts recommending to avoid I’d some fruits ie grape fruit etc..I just had a Cup of licorice tea and as an after thought decided to check if it potentially inhibited CYP3A4..I think it does..my concern is has this one cup of licorice
Damaged my chances for a sussessful outcome re treatment..It’s only early days for me re commencing treatment ..Feeling worried .. I’m due to take my 3rd dose of Sol/dac tonight
Any advise would be appreciated
Tx naive. GT3a
Female
Diagnosed 1996Start 25/2/16
VL 62700
F0
hb 141
ALT 36
ALP 814 week test
VL UND
ALT 18
ALP 70Additional 4 weeks Tx
Start 19.5.1627 February 2016 at 8:17 am #12794I’m no Dr, but I wouldn’t think it has harmed your chances. Especially since your intake of tea and your dose is staggered.
Genotype 3
VL 4,100,000
ALT 101 AST 71
Treatment Naive
Started Sof/Dac Jan 12, 2016
VL= <15 4 weeks in. AST/ALT normal.
VL=UNDETECTED 8 weeks in.
SVR4= Virus back. 3,300,000Started generic Epclusa Sep. 23, 2017
4 weeks in <15 *Detected.
12 weeks in <15 *Not Detected.
16 weeks in <15 *Not Detected.
Finished 24 weeks treatment 3-17-18
SVR5 <15 Not Detected.
SVR 20 <15 Not Detected.
SVR 44 <15 Not Detected.Thank you Jesus.
Thank you Dr. James27 February 2016 at 8:27 am #12795Appreciate your speedy/helpful response Spit Dog…just me being jittery I guess..I received meds approx 3 weeks ago..it’s taken me this long to bite the bullet and commence treatment
Tx naive. GT3a
Female
Diagnosed 1996Start 25/2/16
VL 62700
F0
hb 141
ALT 36
ALP 814 week test
VL UND
ALT 18
ALP 70Additional 4 weeks Tx
Start 19.5.1627 February 2016 at 8:41 am #12796Hi and welcome,
Also not a Dr but with the one cup you will be fine, liquorice has been identified as a cyp3a4 inhibitor but I couldn’t find anything on how strong the effect was. As splitdog says and given you are only two days into treatment that won’t be a problem, just don’t keep drinking it. If you search the site for “CYP3a4” you should find plenty on what items to avoid.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
27 February 2016 at 8:46 am #12797Jack, I’m on the same (Sof/Dac) and am on week 6. I have virtually no side effects. Are you experiencing any?
Genotype 3
VL 4,100,000
ALT 101 AST 71
Treatment Naive
Started Sof/Dac Jan 12, 2016
VL= <15 4 weeks in. AST/ALT normal.
VL=UNDETECTED 8 weeks in.
SVR4= Virus back. 3,300,000Started generic Epclusa Sep. 23, 2017
4 weeks in <15 *Detected.
12 weeks in <15 *Not Detected.
16 weeks in <15 *Not Detected.
Finished 24 weeks treatment 3-17-18
SVR5 <15 Not Detected.
SVR 20 <15 Not Detected.
SVR 44 <15 Not Detected.Thank you Jesus.
Thank you Dr. James27 February 2016 at 8:57 am #12798Just getting a response from you guys makes me feel less anxious..thanks for responding to me
Tx naive. GT3a
Female
Diagnosed 1996Start 25/2/16
VL 62700
F0
hb 141
ALT 36
ALP 814 week test
VL UND
ALT 18
ALP 70Additional 4 weeks Tx
Start 19.5.1627 February 2016 at 9:00 am #12799Hi Spitdog
Only 2 days in..no sides so far..(touch wood)
Tx naive. GT3a
Female
Diagnosed 1996Start 25/2/16
VL 62700
F0
hb 141
ALT 36
ALP 814 week test
VL UND
ALT 18
ALP 70Additional 4 weeks Tx
Start 19.5.1627 February 2016 at 10:45 am #12805nah, can’t see one cup throwing off 12 weeks of killer meds, but like everyone else said,
Stop doing that thing!
GT 2b; since 80’s, no prior tx, sofosbuvir and daclatasvir compounded from API’s at Kingswood Pharmacy in Sydney, started tx nov 6,2015, undetected at 4 wks, UND at 8 weeks, UND at 1 week after EOT, UND at 4 weeks after EOT and UND at 8 weeks after EOT. I feel GOOD!! I knew that I WOULD!””
10 March 2016 at 6:48 pm #13630 -
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