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  • 23 July 2016 at 8:39 pm #21279
    Avatar photoFara
    • Topics: 1
    • Replies: 82
    • Total: 83
    • Guardian Angel
    • ★★★★★
    @fara

    Congratulations Meg! :+1:

    HCV since 35-40yrs., GT 1a , Dx 2004; VL 4-5 mil, F2-3
    Tx sof/led started 3/4/16
    4wks VL <15
    9 weeks VL UND, ; Alt-15,Ast-13
    16 weeks VL UND Alt-20, Ast-22;
    EOT 24 wks UND
    SVR 4 UND
    SVR 12 UND, Alt.15, Ast. 17
    SVR 24 UND

    24 July 2016 at 2:32 am #21292
    Avatar photoMeg
    • Topics: 3
    • Replies: 92
    • Total: 95
    • Guardian Angel
    • ★★★★★
    @meg

    Thank you guys! #love

    So…with the completion of 7 weeks of treatment – came all good things and I am feeling way better. :whistle: There is no comparison actually with the “me before” with the “me during” tx.

    But all pretty roses have thorns (although they don’t take away the beauty and fragrance of the flowers) #flower #flower …and so I got a bit unsure on how to go about the cholesterol thorn/ issue. Will it resolve by its own with EOT? Is cholesterol a real culprit still or have doctors changed their opinion about it? Just for some context… I come from a family with heart disease. My mother, her mother and her siblings all died young due heart attacks. I believe I took over my father’s genetics though and don’t think I am at risk. I also always had low BP and have no idea if it has gone up with the DAAs. Something I should check this week. As you can see my cholesterol levels did increase post initiating Tx. Vitamin D and B12 decreased on the other hand. Also I thought I had been immune to Hep A and Hep B but according to these tests the vaccines I took years ago (?!) did not make me immune to them. Another surprise this week I did not like very much.

    Cholesterol levels before (on the right side) and during tx (on the left side)

    CholesterollevelsbeforeandduringtreatmentwithDAAs-2.png

    Vitamin D before and during tx:

    CortisolandVitaminD-2-3.png

    Test for Hep A and Hep antibodies (not sure what to make of them)

    Funções-VacinasHepAeHepB-2.png

    Blood transfusion in 1992 – Diagnosed in 2007
    Tx naive -G1b – F1
    VL 2.270.000
    ALT 40
    Start tx June 4th/2016 with DAAs – Sof/Led from India
    Bloods on two weeks of tx (June 18th)
    AST 17 – ALT 10 – GGT 19
    Virus UND
    Bloods on six weeks of tx (July 16th)
    AST 17 – ALT 8 – GGT 12
    Virus UND
    EOT on August 8th (did 9 weeks and 3 days)

    SVR 4 Virus UND (September 7th)
    AST 13 – ALT 5

    SVR 14 Virus UND (November 12th)

    24 July 2016 at 5:34 am #21300
    Avatar photofretboard
    • Guardian Angel
    • ★★★★★
    @fretboard

    Wow Meg,
    I salute you on your great news!! Keep it coming!! :cheer:

    Benny-2.png

    G1a dx’d in 1992, Biopsy F2 VL 8mill +. Tried tx with Interferon/Riba, back in 2008 didn’t last long it felt horribly ugly!! I stopped tx, after 5 weeks!!
    Started tx 6/1/16 with Harvoni.
    12 Month Labs= UND

    24 July 2016 at 8:39 am #21308
    Avatar photorohcvfighter
    • Guardian Angel
    • ★★★★★
    @rohcvfighter

    Hi Meg,

    looks very very good :).
    About your cholesterol level, any stress lately? As far as I know, there exist a link between stress level and cholesterol.
    Or you can have a look also here : http://www.hc-sc.gc.ca/dhp-mps/prodpharma/sbd-smd/drug-med/sbd_smd_2015_harvoni_173180-eng.php where it is specified that:
    “Ledipasvir was well-tolerated in studies up to six months in the rat and nine months in the dog. The primary effects noted in toxicology studies were decreased weight, weight gain and food consumption and minor increases in cholesterol.”

    Boa saúde :)

    RHF

    In fiecare an HCV ucide peste 500000 oameni.Medicamentele generice pentru hepatita C functioneaza. Nu deveni statistica! Cauta pe Google “medicamente generice pentru hepatita C”.
    HCV kills more than 500000 people every year. HCV generic drugs work. Don’t become a statistic.
    By sharing this Youtube video you might save someone’s life!
    My TX: HEPCVIR-L[generic Harvoni]-India
    SVR52 achieved

    24 July 2016 at 9:07 am #21311
    Avatar photofitz
    • Guardian Angel
    • ★★★★★
    @fitz

    I’m sure Dr James will have some excellent input on the cholesterol numbers, Meg. Hopefully, just a passing blip on the screen. I do see that your Cortisol number is down. Not a doc, but I do know that Cortisol is a stress hormone and lower is good, so you are apparently doing a great job at keeping you stress levels down. Good for you, and for your heart! :+1:

    24 July 2016 at 9:12 am #21312
    Avatar photorohcvfighter
    • Guardian Angel
    • ★★★★★
    @rohcvfighter

    Oups, I missed the info about the cortisol… Thank you Fitz.
    Perhaps a copy/paste error then? (106 instead of 160 :D ) Just kidding….

    RHF

    In fiecare an HCV ucide peste 500000 oameni.Medicamentele generice pentru hepatita C functioneaza. Nu deveni statistica! Cauta pe Google “medicamente generice pentru hepatita C”.
    HCV kills more than 500000 people every year. HCV generic drugs work. Don’t become a statistic.
    By sharing this Youtube video you might save someone’s life!
    My TX: HEPCVIR-L[generic Harvoni]-India
    SVR52 achieved

    25 July 2016 at 3:28 pm #21376
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    I’m sure Dr James will have some excellent input on the cholesterol numbers, Meg. Hopefully, just a passing blip on the screen.

    I’m with fitz on this – just have another look at SVR12. There is nothing overwhelmingly urgent about cholesterol – long term high levels rust your arteries but that takes 20 years.

    YMMV

    26 July 2016 at 12:28 am #21391
    Avatar photoMeg
    • Topics: 3
    • Replies: 92
    • Total: 95
    • Guardian Angel
    • ★★★★★
    @meg

    Yay good to know! Thank you so much for your input Dr Freeman. #love

    Blood transfusion in 1992 – Diagnosed in 2007
    Tx naive -G1b – F1
    VL 2.270.000
    ALT 40
    Start tx June 4th/2016 with DAAs – Sof/Led from India
    Bloods on two weeks of tx (June 18th)
    AST 17 – ALT 10 – GGT 19
    Virus UND
    Bloods on six weeks of tx (July 16th)
    AST 17 – ALT 8 – GGT 12
    Virus UND
    EOT on August 8th (did 9 weeks and 3 days)

    SVR 4 Virus UND (September 7th)
    AST 13 – ALT 5

    SVR 14 Virus UND (November 12th)

    14 September 2016 at 12:09 am #22922
    Avatar photoMeg
    • Topics: 3
    • Replies: 92
    • Total: 95
    • Guardian Angel
    • ★★★★★
    @meg

    Hi everyone I was waiting for a SVR 4 before posting again so since my lab results just came out yesterday here I am with the VERY good news that the HCV RNA bloods came UNDETECTED! :woohoo:

    Such a relief as these last days prior to the labs I was getting a bit paranoid and suspicious I might relapse! One of the reasons was that immediately after EOT I felt great, super great actually for about two weeks but then on weeks 3 and 4 after EOT I felt tired again and some of those pre tx pains in my joints – as well as on the soles of my feet – returned with a ” vengeance” ! OH MY!

    I see now that those sides and fatigue post tx were probably part of the healing process and although I know I have to wait for SVR 12 and SVR 24 to really celebrate and consider myself cured – I am so so happy that I have come this far and so wanted to shared it with all of you.

    My liver is looking pretty good too by the way so I SHOULD just relax from now and enjoy the ride :whistle: until it is time for that SVR 12 test in early November.

    ALT = 5
    AST = 13
    Alkaline Phosphastase = 44
    Bilirubin Total = 0.2
    Albumin = 4.2
    Total Protein = 6.6

    Best wishes to all of you and thank you so much for your presence! #love Hope we all achieve SVR and that those reading this forum who are still undecided to treat with generic DAAs – please take the plunge asap because these meds really work and there is a whole new HEP C life waiting for us! xoxo

    Blood transfusion in 1992 – Diagnosed in 2007
    Tx naive -G1b – F1
    VL 2.270.000
    ALT 40
    Start tx June 4th/2016 with DAAs – Sof/Led from India
    Bloods on two weeks of tx (June 18th)
    AST 17 – ALT 10 – GGT 19
    Virus UND
    Bloods on six weeks of tx (July 16th)
    AST 17 – ALT 8 – GGT 12
    Virus UND
    EOT on August 8th (did 9 weeks and 3 days)

    SVR 4 Virus UND (September 7th)
    AST 13 – ALT 5

    SVR 14 Virus UND (November 12th)

    14 September 2016 at 1:15 am #22923
    Avatar photoAriel
    • Guardian Angel
    • ★★★★★
    @ariel

    Hi Meg
    Thanks for sharing your great news achieving SVR4 is awesome you clearly have got this for sure #flower #flower
    The LFTs are so good gosh our labs in Oz don’t even read under 9 on ALT, I have had it say <9 so you have a really specific reading there too that's the first time I have read ALT at 5. It's very interesting the differences in pathology ranges from place to place it fascinates me.
    You mentioned about a few little niggles after EOT I think a few friends have felt same, I recall a bit of fatigue that I didn't expect. Considering that we are more than just our physical bodies I personally believe there's a psychological and emotional release after treatment and it could make anyone tired or anxious even.
    Just my humble opinion
    The main thing is you are cured and have started on the SVR road towards SVR12 which I am sure you will get just look how wonderfully healthy your liver is that's fabulous
    Congrats again
    Very happy splashes from Ariel #love #flower

    14 September 2016 at 1:15 am #22924
    Avatar photorohcvfighter
    • Guardian Angel
    • ★★★★★
    @rohcvfighter

    Hi Meg,
    Congratulations, these are excellent news!!!
    Stay positive, like you been as until now :) SVR12 is very close ;-)

    Cheers,
    RHF

    In fiecare an HCV ucide peste 500000 oameni.Medicamentele generice pentru hepatita C functioneaza. Nu deveni statistica! Cauta pe Google “medicamente generice pentru hepatita C”.
    HCV kills more than 500000 people every year. HCV generic drugs work. Don’t become a statistic.
    By sharing this Youtube video you might save someone’s life!
    My TX: HEPCVIR-L[generic Harvoni]-India
    SVR52 achieved

    14 September 2016 at 2:33 am #22927
    Avatar photofitz
    • Guardian Angel
    • ★★★★★
    @fitz

    Fantastic news Meg! Those lab numbers are incredible. WOW!!!

    Here’s to SVR 4!!!

    14 September 2016 at 2:46 am #22929
    Avatar photoGreedfighter
    • Guardian Angel
    • ★★★★★
    @greedfighter

    Meg, :cheer: :+1:

    I can’t resist, sorry fitz, ha ha, it’s impossible to top the Leo champagne toast, lol! :cheer:

    Attachments:
    • giphy[1].gif
    14 September 2016 at 3:47 am #22931
    Avatar photoHieupham
    • Topics: 9
    • Replies: 50
    • Total: 59
    • Recovery Champion
    • ★★★★
    @hieupham

    Hi Meg,
    :woohoo: :woohoo: :woohoo:

    Congratulations!
    #flower #flower #flower

    Nishkama Karma
    Cùng nhau loại bỏ Viêm gan C trên khắp thế giới!

    14 September 2016 at 5:41 am #22933
    Avatar photoCC2B
    • Guardian Angel
    • ★★★★★
    @cc2b

    Excellent news :+1:
    Congratulations Meg!
    On to SVR 12
    #flower #flower #love

    GT2b diagnosed 10/2015
    since: unknown
    11/20/15 VL= 214,070
    12/4/15 ALT=18 AST= 24
    1/16/16 started sof/dac
    2/13/16 @4wks VL=UND ALT=13 AST=22
    3/12/16 @8wks VL=UND ALT=10 AST=18
    4/9/16 EOT VL=UND ALT=11 AST=19
    9/23/16 SVR24 ALT=11 AST=22

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