REDEMPTION is "Official" in the U.S.!

This topic has 14 replies, 10 voices, and was last updated 8 years, 11 months ago by Tina-Hill-facebook.

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22 January 2016 at 12:53 am #10023
mgalbrai
- Topics: 28
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- Total: 1,326
- Guardian Angel
@mgalbrai
This IS BIG!!!

Way to go Doc!!

https://www.clinicaltrials.gov/ct2/show/NCT02657694?term=redemption&rank=1

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
22 January 2016 at 12:58 am #10024
splitdog
- Topics: 5
- Replies: 374
- Total: 379
- Guardian Angel
@splitdog
Thank you Dr. Freeman.

splitdog@roadrunner.com

Genotype 3
VL 4,100,000
ALT 101 AST 71
Treatment Naive
Started Sof/Dac Jan 12, 2016
VL= <15 4 weeks in. AST/ALT normal.
VL=UNDETECTED 8 weeks in.
SVR4= Virus back. 3,300,000

Started generic Epclusa Sep. 23, 2017

4 weeks in <15 *Detected.
12 weeks in <15 *Not Detected.
16 weeks in <15 *Not Detected.
Finished 24 weeks treatment 3-17-18
SVR5 <15 Not Detected.
SVR 20 <15 Not Detected.
SVR 44 <15 Not Detected.

Thank you Jesus.
Thank you Dr. James
22 January 2016 at 1:05 am #10025
Vororo
- Topics: 25
- Replies: 307
- Total: 332
- Guardian Angel
@vororo
Dr James does it again!

Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).
22 January 2016 at 1:25 am #10026
LondonGirl
- Topics: 16
- Replies: 1,348
- Total: 1,364
- Guardian Angel
@londongirl
Wow – That ‘s totally awesome !!
Respect to Dr F
MonkMed too !

Hey, let’s not forget the patients on Redemption

GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
22 January 2016 at 2:02 am #10029
Paul-Jarman-facebook
- Topics: 8
- Replies: 373
- Total: 381
- Guardian Angel
@paul-jarman-facebook
Huge news indeed

Two time relapser.

SVR 4 achieved 12/16 at last
SVR 12 achieved 22/02/2017 The Bastard has been defeated

GT 3 – about 28 yrs with HCV
22 January 2016 at 2:24 am #10032
2b
- Topics: 17
- Replies: 332
- Total: 349
- Guardian Angel
@2b
There it is!! I’m gonna go post this ‘somewhere’

UPDATE: wow, volleyboss beat me to it!!
eviljoy loves her trials for her followers, she probably doesnt’ realize these are the generics she rails against.

GT 2b; since 80’s, no prior tx, sofosbuvir and daclatasvir compounded from API’s at Kingswood Pharmacy in Sydney, started tx nov 6,2015, undetected at 4 wks, UND at 8 weeks, UND at 1 week after EOT, UND at 4 weeks after EOT and UND at 8 weeks after EOT. I feel GOOD!! I knew that I WOULD!””
22 January 2016 at 2:43 am #10034
mgalbrai
- Topics: 28
- Replies: 1,298
- Total: 1,326
- Guardian Angel
@mgalbrai
I didn’t intend to steal your thunder…

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
22 January 2016 at 3:34 am #10047
dointime
- Topics: 29
- Replies: 325
- Total: 354
- Guardian Angel
@dointime
Yes it is big, and in so many ways.

– It is not sponsored by Big Pharma.
– The sof/dac combo will finally get the trial results that have been sorely lacking.
– The generics naysayers will have nowhere to hide.

… and so much more which will no doubt unfold in the fullness of time.

dt
22 January 2016 at 3:50 am #10049
emilio
- Topics: 13
- Replies: 368
- Total: 381
- Guardian Angel
@emilio
This is awesome news and hopefuly will give some US cred to generics and fixhepc. Posting now. Em
22 January 2016 at 5:37 am #10063
2b
- Topics: 17
- Replies: 332
- Total: 349
- Guardian Angel
@2b
not at all, funnier than hell I thought when I saw your post there, , im staying far away from it so she doesn’t catch on and maybe it will survive longer in her temple of un-reason.

GT 2b; since 80’s, no prior tx, sofosbuvir and daclatasvir compounded from API’s at Kingswood Pharmacy in Sydney, started tx nov 6,2015, undetected at 4 wks, UND at 8 weeks, UND at 1 week after EOT, UND at 4 weeks after EOT and UND at 8 weeks after EOT. I feel GOOD!! I knew that I WOULD!””
22 January 2016 at 11:31 am #10081
Tina-Hill-facebook
- Topics: 28
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- Total: 733
- Guardian Angel
@tina-hill-facebook
Great news about the Redemption trials in the US!!!

Do you think it’s possible for insurance to pay for it?..(sorry I’m not that familiar with US health insurance policies)

SVR 24
22 January 2016 at 4:34 pm #10097
mgalbrai
- Topics: 28
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- Guardian Angel
@mgalbrai
That is above my pay grade. If I were an insurer, I would be huddling with my legal beagles coming up with a release from liability form for clients to sign who opted for clinical trial treatment coverage.
Since it makes sense, I doubt they will do that.
Mike

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
22 January 2016 at 5:03 pm #10098
dointime
- Topics: 29
- Replies: 325
- Total: 354
- Guardian Angel
@dointime
Generally speaking, I have never heard of a medical insurer who would cover “experimental treatment”, which is what trials usually come under. They usually only cover treatment approved by the regulatory body, ie. the FDA, NHS, PBS etc. But this is an interesting case because brand name sof, led and dac are all approved drugs. So what category will be applied to the generic sof, led and dac used in this trial?
ie. “experimental” or “approved”.

I guess somebody will have to make a claim to find out.
dt
22 January 2016 at 8:14 pm #10107
The_1B_Dude_Abides
- Topics: 1
- Replies: 12
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- Acolyte
@the_1b_dude_abides
This is huge!
Forwarded to my dr. and am digitizing my bloods as we speak
Thank you for all your hard work, Doctor!
22 January 2016 at 10:32 pm #10119
Tina-Hill-facebook
- Topics: 28
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- Guardian Angel
@tina-hill-facebook
dointime wrote:

Generally speaking, I have never heard of a medical insurer who would cover “experimental treatment”, which is what trials usually come under. They usually only cover treatment approved by the regulatory body, ie. the FDA, NHS, PBS etc. But this is an interesting case because brand name sof, led and dac are all approved drugs. So what category will be applied to the generic sof, led and dac used in this trial?
ie. “experimental” or “approved”.

I guess somebody will have to make a claim to find out.
dt

Yeah both yourself and Mike make some good points, when I started treatment I had to sign a disclaimer with my aftercare provider – even though the medication I was taking was on the Med Safe list, much the same as Sof, Led & Dac are approved by the FDA.

I think it would be well worth further investigation.

SVR 24
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