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  • 21 December 2017 at 12:05 am #27170
    Smp123
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    • Novice
    • ★
    @smp123

    Hi, I am about to start daclatasivr/ sofosbuvir and am curious to know if there is anything specific to avoid while on treatment that I may not have heard of ? Also what time of day is best for taking pills to combat side effects? Thank you!

    21 December 2017 at 3:14 am #27171
    Avatar photoGreedfighter
    • Guardian Angel
    • ★★★★★
    @greedfighter

    Hi Smp123,

    I believe you need to avoid taking Milk Thistle and St. John’s Wart.

    21 December 2017 at 10:54 am #27174
    Avatar photoMnem
    • Guardian Angel
    • ★★★★★
    @mnem

    Hello Smp123,
    It’s great to have you on the forum. To check for interactions this is the best online tool:
    http://www.hep-druginteractions.org/checker

    Go well, Mnem

    G2, infected maybe in 1971?
    Diagnosed HVnon-A non-B 1980s, revised to HVC 1990’s.
    Treatment naive. Fibroscan & bloods all normal ranges.
    Viral load 7million,
    began Redemption trial4, 12-week generic Sof/Vel (Incepta) 2017. Week 4 UND, Week 12UND, SVR24
    Thank-yous to my doctor for the script, to Jan at FixHepC for wrangling, and to Dr Freeman for courage.
    Kia kaha e hoa ma!

    21 December 2017 at 1:13 pm #27175
    Avatar photoMnem
    • Guardian Angel
    • ★★★★★
    @mnem

    Hello again Smp123,
    About taking the meds: It’s really up to you to decide when. The big thing is to take them at the same time every day; and to take them every day. Do not miss a beat. If you forget a dose then take it soon as possible.

    :idea: My own system involved every morning without fail, waking then taking.

    As back up I kept a stash in the bag I take out with me each morning. That way I always had the meds to hand if needed. So if you #duck #duck #duck #duck #duck #duck #duck #duck you will always remember to remember to take the drugs

    G2, infected maybe in 1971?
    Diagnosed HVnon-A non-B 1980s, revised to HVC 1990’s.
    Treatment naive. Fibroscan & bloods all normal ranges.
    Viral load 7million,
    began Redemption trial4, 12-week generic Sof/Vel (Incepta) 2017. Week 4 UND, Week 12UND, SVR24
    Thank-yous to my doctor for the script, to Jan at FixHepC for wrangling, and to Dr Freeman for courage.
    Kia kaha e hoa ma!

    21 December 2017 at 2:23 pm #27177
    avatar876.jpegGaj
    • Guardian Angel
    • ★★★★★
    @gaj

    Hi Smp123 & welcome. :)

    I’m not sure how you are viewing the forum currently but if you scroll to the top of this page you will see set of blue tabs that provide shortcuts to various areas. If you click on the one labelled “Index” this will take you to forum topics by category. Most of the information you ask about can be found in the Experts Corner section under the heading .

    Here is a link to that area, the yellow ‘pinned’ posts at the top cover most of the Daclatasvir relevant information although a read through the others may also assist.

    https://fixhepc.com/forum/drug-interactions.html

    (The “hep-drugsinteractions” checker that Mnem links is excellent but more geared towards medicines/pharmaceuticals than everyday foods and drinks, etc. though it does list some of the more well known consumables like Grapefuit)

    G3a since ’78 – Dx ’12 – F4 (2xHCC)
    24wk Tx – PEG/Riba/Dac 2013 relapsed
    24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
    16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
    SVR7 – 22/06/17 UND
    SRV12 – 27/07/17 UND
    SVR24 – 26/10/17 UND
    :cheer: :cheer: :cheer:

    21 December 2017 at 2:30 pm #27178
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hello Smp123,

    You’ve been given some good pointers already. This is a good thread discussing Daclatasvir

    https://fixhepc.com/support-forum/drug-interactions/611-cyp3a4-inhibitors-and-daclatasvir-fruits.html

    Taurine is in red bull and other energy drinks and some body building supplements. We got it added to the literature because we saw people failing on treatment because of it.

    You will find the official manufacturers detailed instructions here: https://fixhepc.com/medication-information.html

    There is both the simple patient info version and the complicated doctor one.

    YMMV

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