Thrush and/or Thirst = Check for diabetes

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9 June 2016 at 3:15 am #18716
Dr James
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@fixhepc
There are many extra-hepatic manifestations of HCV.

Diabetes is one of them, and uncontrolled diabetes decreases SVR rates, so you need to care.

Common symptoms of diabetes include thirst and the yeast infection thrush.

Thrush can be a white mouth, a sore mouth, a sore back passage, a red rash under the breasts, in the crutch, or on the feet.

Diabetes is quite simply diagnosed with a fasting blood sugar and this can be done in 30 seconds with a finger prick blood sample.

If your blood sugar is over 11 mmol then that’s it – you are diabetic. No if’s ands buts or maybes. If it’s between 7-11 it needs a glucose tolerance test.

If you have diabetes, or develop it on treatment with DAAs then treating it with Metformin is a damn good idea.

Weight loss is known to reduce blood sugar levels in type 2 diabetics, so it is possible for many people to use this as a non-drug method of fixing the disease.

While HCV is a nasty disease so is diabetes so please don’t ignore the symptoms. The test is simple and so is the treatment if required.

YMMV
9 June 2016 at 6:26 am #18725
GT2
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@gt2
Can anyone recommend a reliable and reasonably accurate blood glucose meter?

1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2
22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Na√Øve)
10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India
09/05/16: ALT 34, VL: NOT Detected 🙂 , FBG 11.9
17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72
🙂 (Accu-Chek Mobile & Omron Auto BP Monitor) 🙂
9 June 2016 at 6:41 am #18727
Meg
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@meg
Thank you Dr Freeman. I will make sure to get a blood test for that.

Blood transfusion in 1992 – Diagnosed in 2007
Tx naive -G1b – F1
VL 2.270.000
ALT 40
Start tx June 4th/2016 with DAAs – Sof/Led from India
Bloods on two weeks of tx (June 18th)
AST 17 – ALT 10 – GGT 19
Virus UND
Bloods on six weeks of tx (July 16th)
AST 17 – ALT 8 – GGT 12
Virus UND
EOT on August 8th (did 9 weeks and 3 days)

SVR 4 Virus UND (September 7th)
AST 13 – ALT 5

SVR 14 Virus UND (November 12th)
9 June 2016 at 7:13 am #18729
Dr James
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@fixhepc
Accu-chek is a pretty standard brand.

It’s cheapest to get a starter kit that has the lancets, the push button staby jaby ouchy tool, test strips and the meter that reads the strips.

http://www.chemistwarehouse.com.au/buy/66103/Accu-Chek-Mobile-Blood-Glucose-Meter-Kit

YMMV
9 June 2016 at 7:46 am #18730
GT2
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@gt2
Thank you Dr Freeman.

As I’ve already said, my diabetes symptoms have dissipated over the last few weeks, however, doubt has been cast in my mind … so, it’s always better to be safe than be sorry …

Thanks for your support.

GT2

1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2
22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Na√Øve)
10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India
09/05/16: ALT 34, VL: NOT Detected 🙂 , FBG 11.9
17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72
🙂 (Accu-Chek Mobile & Omron Auto BP Monitor) 🙂
9 June 2016 at 10:58 am #18742
beaches
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@beaches
Thank you Doctor Freeman.
I have been thirsty throughout treatment and thought that was a Sx because quite a few people mentioned it. My fasting blood sugar has always been quite low, around 4.
I’m doing my EOT bloods tomorrow but am pretty sure there won’t be a glucose test because the Hep C nurse at RPA said I didn’t need to be fasting.
I’ll see how the thirst is over the next few weeks as the Harvoni leaves my system.

Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
10 June 2016 at 2:52 am #18777
Ariel
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@ariel
Hi all
With anything it’s always best to get checked asap
I do have oral thrush, you may too! I have had soooo many chemicals pumped into me over the past few years if this is the last thing to be re-balanced I don’t mind! Better than rotted feet from peginf riba ha!

Just finished my GP session

No I don’t have diabetes

Ariel
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10 June 2016 at 11:29 am #18803
Price
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@price
beaches,
You can’t judge blood sugar based on how thirsty you are. Your body can become used to having high blood sugar and the symptoms may decrease.

Some doctors think that the hypoglycemic of today is the diabetic of tomorrow. Because when your blood sugar starts going up, the pancreas works faster to make enough insulin to keep your blood sugar within the normal limit but sometimes it produces too much insulin, which can cause hypoglycemia (like your 4). Eventually, the pancreas might not be able to keep up the fast pace and the blood sugar starts going up and the person becomes a diabetic.

So it’s best to get your blood sugar checked.

P.
10 June 2016 at 12:16 pm #18811
beaches
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- Guardian Angel
@beaches
Random (not fasting)reading 1 hour after a gelato. Normal range. Think I’m ok.

Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
10 June 2016 at 12:48 pm #18813
Ariel
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@ariel
My reading had milk and a sports drink involved in my fasting lol
Nah no diabetes here either
Must be our ocean lifestyle Beaches
Ariel splashing you from Siberia here get out the steamer time!
10 June 2016 at 12:50 pm #18814
beaches
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- Guardian Angel
@beaches
Ariel wrote:

Must be our ocean lifestyle Beaches
Ariel splashing you from Siberia here get out the steamer time!

Splashes back from the sewage outlet. At least it’s warm. I’ll be swimming undeterred tomorrow

Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
10 June 2016 at 12:54 pm #18815
Ariel
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- Guardian Angel
@ariel
Beaches you never know what is in the water after last weekend don’t catch a fungal infection!!! A certain politician swims near there ick:' />
Ha! Have a great swim it’s pouring here
Ariel
10 June 2016 at 1:46 pm #18819
beaches
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- Total: 760
- Guardian Angel
@beaches
Ariel wrote:

Beaches you never know what is in the water after last weekend don’t catch a fungal infection!!! A certain politician swims near there ick:' />

Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
11 June 2016 at 12:34 pm #18913
Price
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- Guardian Angel
@price
The product monograph for Sovaldi (page 12) lists 6% blood sugar >250 (13.9). That’s diabetes but they don’t list diabetes. It also lists fungal infections (page 10). There are actually quite a few side effects that are not listed on the medication insert.

http://www.gilead.ca/pdf/ca/sovaldi_pm_english.pdf

Things like palpitations, chest pain, visual impairment, basal cell carcinoma and amaurosis fugax (a transient monocular or binocular vision loss that appears as a “curtain coming down vertically into the field of vision in one eye;”

That sounds just like a detached retina. One of our Vets had a detached retina while on Harvoni.

The Harvoni monograph lists blood sugar >160 (8.9) in 9% for the 8 week group, 10% for the 12 week group and 12% for the 24 week group.
Again, a fasting blood sugar of 160 is diabetes but they don’t list diabetes or say whether it resolved.

P
11 June 2016 at 12:41 pm #18914
Price
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- Guardian Angel
@price
You need to do it fasting because it can also tell you if you’re insulin resistant.

P.
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