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TOPIC: So, the battle is joined!

So, the battle is joined! 3 years 10 months ago #6633

zhuk
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Thought after reading so many inspiring stories of other's journeys here, I would kick off with my own. I haven't shared much detail about my background before, so sorry for the essay in advance lol

After a fairly excruciating wait of a month since receiving my meds, an auspiscious New Year's day start! Really wanted to get onto the Redemption-2 trial - I can never repay the generosity of those here and the Buyer's Club who made this possible, but hopefully throwing in my contribution to help Dr James might go some small way towards it

A bit of preliminary info on my pre-tx condition. GT1a, 27 years infected, diagnosed 1990 (which would have been the year it was isolated from merely 'non-A/non-B' status) Years I forgot about it/repressed to a certain extent, and had a fairly fatalistic POV. Kind of like the bullet that's out there with your name on it - or not!

During those decades somehow I managed to keep to a F0 score (no idea how heh) but in recent years I've come to suspect that a lot of symptoms might not be caused by other conditions as I'd thought. The sometimes crushing fatigue (hey my 92-yr old mother has more energy a lot of the time lol), joint/muscle pain which might not be completely chronic pain after all, weird abdominal issues with no apparent cause, those irritating & unnerving stinging/congested liver sensations, the grasping for words you're sure you knew once...all those familar symptoms.

Last pre-tx stats:

Ended up with a relatively small VL - 262,000 (no idea what it was until a month ago, so that was a surprise)
ALT - 40 (used to be in the high 50s-60s until I started milk thistle a few years back)
AST - 26
GGT - 13
Bilirubin - 5
Platelets - 411
Edit: Fibroscan 04/12/15 - 2.9

Prescribed Mesochem sof/dac 12 weeks by Dr J, and its all go from here. Not expecting any issues, although I'm open to the possibility of extra sx purely due to my lower than average weight of 52kg, giving a higher gram per kg effect particularly with the dac, as the doc informed me could be the case. Planning to try and stick it out without any dosage decrease, maybe the bit extra will give a kind of added "insurance"!

So, I'm locked, loaded and ready as I'll ever be for the battle. I reckon the odds are very definitely on my side

GT1a since 1988, diagnosed 1990
F0, tx naive
VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 - 2.9
Started Mesochem sof/dac 12 weeks 01/01/2016
11/02/2016 - 6 weeks UNDETECTED
AST 26
ALT 26

Last Edit: 3 years 10 months ago by zhuk.

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So, the battle is joined! 3 years 10 months ago #6634

mgalbrai
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Damn the torpedoes, full speed ahead!
No more "run silent, run deep"!!
Engage and destroy!
Good hunting Zhuk!
86

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G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24

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So, the battle is joined! 3 years 10 months ago #6635

darbara Offline Elite Member Posts: 176 Thank you received: 192 Karma: 3	Happy New Year I know its GONNA be a happy one for you. Enjoy the ride. 3 weeks done here 9 to go.
	Treatment naive F 3/4 Genotype 1 a & b V/L 17 MILLION Started Harvoni 11th Dec 2015 for 12 weeks 4 weeks VL UND 6 WEEKS ALT 32, AST 34 EOT 03/03 2016 ! UND ALT 34, AST 26 04.04.2016 SVR 4 26.05.2016 SVR 12 16.08.2016 SVR 24 The administrator has disabled public write access. The following user(s) said Thank You: zhuk, magpie

So, the battle is joined! 3 years 10 months ago #6636

Gaj Offline Moderator Optimist :-) Posts: 1436 Thank you received: 3081 Karma: 32	Hi zhuk, About time you joined in! I must say your stats look good and agree the odds are definitely on your side. Start mowing them virions down!
	G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND The administrator has disabled public write access. The following user(s) said Thank You: Ariel, zhuk, magpie

So, the battle is joined! 3 years 10 months ago #6638

Jolie Offline Premium Member Posts: 131 Thank you received: 111 Karma: 2	What a great way to start the New Year! I wish you symptoms free & enjoyable tx journey, jolie xxxx
	Geno 3, Fibro 8.7 pKA, tx experinced in 2005 - Peg/Riba, relapsed. Started tx 1/12/2015 with Indian Sofo & Chinese Dac. 5 weeks result all normal, ALT 18 - down from ALT 73 at the start of tx. 5 weeks HCV PCR RNA - UND. - down from 2 ML 9 weeks HCV PCR RNA - UND. The administrator has disabled public write access. The following user(s) said Thank You: zhuk, magpie

So, the battle is joined! 3 years 10 months ago #6641

Debs Offline Elite Member Posts: 251 Thank you received: 437 Karma: 3	All the best Zhuk, New year, new you! Not far behind you, will be good to read your posts! Deb X
	Geno 1a, F1, tx naive, had it 35 yrs. Started Cipla HepcvirL on 12/01/16 Starting VL 490,000 At 16 days in <15 4 week results: UND 8 week results: UND 5 weeks EOT alt 25 SVR 15 - Not Detected 6 months EOT - Not Detected Last Edit: 3 years 10 months ago by Debs. The administrator has disabled public write access. The following user(s) said Thank You: LondonGirl, zhuk, magpie

So, the battle is joined! 3 years 10 months ago #6650

isaing4 Offline Elite Member Stop saying 'I wish' and start saying 'I will'. :) Posts: 239 Thank you received: 423 Karma: 5	Hi zhuk, Yes chance is on your side. Good start position. Get rid of all remaining viruses! The only side effect I noticed is gaining weight!
	HCV since I don't know. Diagnosed in 2010. GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive, started 12 wks Twinvir on 06.12.2015. Feeling great and grateful virus not detected 06.02.2016 & SVR24 This email address is being protected from spambots. You need JavaScript enabled to view it. The administrator has disabled public write access. The following user(s) said Thank You: Ariel, zhuk

So, the battle is joined! 3 years 10 months ago #6653

Enkel
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Zhuk.

With fibro F0 there are no sides

What is the norm of bilirubin?

Good luck

Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured

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So, the battle is joined! 3 years 10 months ago #6655

mgalbrai
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Bilirubin norms: (for my lab)
Direct: 0.0-0.2
Total: 0.2-1.5

M

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G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24

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So, the battle is joined! 3 years 10 months ago #6656

Enkel Offline Platinum Member Posts: 329 Thank you received: 165 Karma: 0	M the value of Zhuk should be 0.5, it is impossible to be 5
	Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety. Started Twinvir 12/12/15. Two weeks ALT 17 at 2 weeks Viral Load UND at 2 weeks ALT 13.5 at 7 weeks EOT ALT 10.5 at 15 weeks EOT ALT 13 at 27 weeks EOT, VL UND, Cured The administrator has disabled public write access.

So, the battle is joined! 3 years 10 months ago #6657

mgalbrai
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Yes,
My thoughts exactly.
He should have GREAT results with his overall stats!
You readin' this Warrior Zhuk???
M

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G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24

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So, the battle is joined! 3 years 10 months ago #6658

Enkel
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I really could not believe to be F0 for 30 years with hepc. He is strong and have salamander-like regeneration abilities

Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured

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So, the battle is joined! 3 years 10 months ago #6660

Gaj Offline Moderator Optimist :-) Posts: 1436 Thank you received: 3081 Karma: 32	Enkel wrote: M the value of Zhuk should be 0.5, it is impossible to be 5 Hi Guys, I suspect your results are per decilitre? Zhuk's, like mine will probably be per litre. So yes, what you would call 0.5 is 5 in Australia. I often need to convert when comparing results or using things like MELD calculators.
	G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND The administrator has disabled public write access. The following user(s) said Thank You: zhuk

So, the battle is joined! 3 years 10 months ago #6661

2b
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Get em Zhukster, the nasty little buggers will be running for the hills and trying to hide in the outback of your innards, but every last one of em will soon bite the dust.

GT 2b; since 80's, no prior tx, sofosbuvir and daclatasvir compounded from API's at Kingswood Pharmacy in Sydney, started tx nov 6,2015, undetected at 4 wks, UND at 8 weeks, UND at 1 week after EOT, UND at 4 weeks after EOT and UND at 8 weeks after EOT. " I feel GOOD!! I knew that I WOULD!"

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So, the battle is joined! 3 years 10 months ago #6665

sonix Offline Elite Member Music is life Posts: 165 Thank you received: 359 Karma: 2	Welcome to the Tx club, zhuk. I don't know how you held out for so long, I had to start same day I received them.
	M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15. SVR4 at 7Apr16 ALT 22 AST 22 SVR12 at 9Jun16 ALT 23 AST 25 Melbourne, Australia The administrator has disabled public write access. The following user(s) said Thank You: zhuk