Roger Esnouf - FixHepC - Page 5 of 14

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25 February 2016 at 5:01 am in reply to: Viekira RBV Failure – Retreatment #12640
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
I don’t have much faith in Viekira Pak. A friend of mine refused a free trial due to reports of death among cirrhotic patients, he’s Gt1a, F4.
Good luck with new treatment. I’m sure with your RAV information now at hand a suitable course can be found. Dr Freeman is da bomb!

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
24 February 2016 at 3:57 am in reply to: Sonix Tx Log #12543
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
6.5 week blood results – undetected! Thanks Hieu for the phone call last Friday.

I’m still feeling a fatigued (or lazy?) but find if I have to do something, I just need to start doing it and the energy comes somehow.
I work part time at one of Melbourne’s premier music venues, setting up and operating sound and lighting. I had a little break for 6 weeks and did my first show back with Albert Hammond from The Strokes a couple days ago. It was a warm humid day and I had excessive sweating most of the time, but drank lots of water and a little soft drink and managed to keep up despite being crazy hectic most of the night with 3 bands on 2 stages all needing me to help.
The sides are manageable although I attribute some of the sweating to Tx. I was speaking to a friend who is doing 24 weeks sof/dac and he mentioned feeling “toxic”. This is something I haven’t seen mentioned here before but I know what he means as I feel the same.
Just over 2 weeks to go and hopeful the remaining sides will abate after EOT.
To infinity and beyond!

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
24 February 2016 at 3:16 am in reply to: 999 Members! #12541
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
Considering the number of members is only a small percentage of the people this site has helped, this is a good milestone.
1008 members atm!

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
24 February 2016 at 3:12 am in reply to: HCV New Drugs Blogspot #12540
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
That last article is curious considering BMS withdrew application for approval of asuneprevir (in combination with daclatavir) in Oct 2014 Because –

In clinical trials, BMS’s combination, on the other hand, cured just 82 percent to 90 percent of those with genotype 1b after 24 weeks.

Source – https://www.hepmag.com/article/asunaprevir-end-26284-925493039

I wonder what changed, as they are reporting higher SVR rates in this trial?

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
23 February 2016 at 3:03 am in reply to: Big Pharma spending 19:1 Marketing:R&D #12473
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
No surprise there. I wish we could bring back the classic old values of humanity and ethics.

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
23 February 2016 at 2:43 am in reply to: Dan’s Twinvir story #12470
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
Dan wrote:

As I already mentioned, the VL was detected at that time, but doctor showed me the comments ” Unable to quantify, antibodies detected”.

What does this mean?

I would take this to mean HCVDNA detected but

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
22 February 2016 at 12:08 pm in reply to: Dan’s Twinvir story #12434
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
As mentioned elsewhere, grapefruit is an inhibitor for CYP3A4 enzyme which metabolises Daclatavir. Twinvir is Ledipasvir and Sofosbuvir so I’m guessing you’re good.

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
22 February 2016 at 11:54 am in reply to: Drinking alcohol #12431
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
I lost faith in psychologists, although I’ve only ever seen two. The last one kept on bringing up the suicide of an ex-housemate with whom I did not get along with well and was not especially friendly. He hanged himself a few months after I moved out. I just wanted to forget it as I didn’t consider it a big deal (I’ve lost a few much closer friends) but she kept on bringing it up. Maybe she was right, but I didn’t think so and stopped seeing her after 4 visits.

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
22 February 2016 at 11:29 am in reply to: FixHepC – Party Playlist #12427
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
I love Spiritualized.

Think I’m in love
Probably just hungry

https://www.youtube.com/watch?v=Fcj7WIVWRYo

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
22 February 2016 at 10:00 am in reply to: What was that Hep C? #12422
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
”Lynne-Francis-facebook” wrote:

That is awesome news!!!!!!!!!!!!!!!!!! Go you And I luv Grumpy Cat

Grumpy Cat doesn’t love you but would acknowledge your existence.

Congrats, Chester!

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
22 February 2016 at 9:57 am in reply to: Countdown begins for the Magpie #12421
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
I had most of those symptoms before treatment.

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
22 February 2016 at 3:19 am in reply to: HCVRNA not detected #12399
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
Me too! Undetected at 6.5 weeks.

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
21 February 2016 at 5:44 am in reply to: Quote of the day #12367
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
Just spotted this on Quora –

A Harvard psychologist once said, you’re more likely to ACT yourself into FEELING, than FEELING yourself into ACTION. That means you cant sit around hoping for motivation. You’ll need to ACT

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
17 February 2016 at 6:29 am in reply to: Quote of the day #12066
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
CJ wrote:

Life always offers you a 2nd chance, it’s called tomorrow!
x

Reminds me of a sign near the Eumundi turnoff from the highway for Joe’s Waterhole pub (years ago) –
Free Beer Tomorrow!

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
17 February 2016 at 5:58 am in reply to: Taurine Daclatasvir and Treatment Failure #12064
sonix
- Topics: 7
- Replies: 158
- Total: 165
- Guardian Angel
@sonix
Johnboy wrote:

Green tea extract is very bad for the liver. A Perth man was recently at death’s door from it and he needed a new liver. They had to give him one that was infected with HBV.

This is the story you mentioned –
http://www.abc.net.au/news/2016-02-14/man-faced-death-after-taking-popular-weight-loss-product/7162378

Green tea extract was mentioned as the probable cause although doctors were uncertain. I would guess it was present in large quantities in the “weight-loss product purchased online”.

With a little more searching I found vastly conflicting reports, from a girl who got very sick from 3 cups of green tea a day:
http://www.techtimes.com/articles/88334/20150927/teen-who-drank-too-much-green-tea-develops-hepatitis-and-turns-yellow-because-of-liver-damage.htm

to a report that it helps fatty liver:
http://www.liversupport.com/green-tea-promotes-a-lean-liver/

M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
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