Dan's Twinvir story

This topic has 360 replies, 38 voices, and was last updated 7 years, 6 months ago by LondonGirl.

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2 December 2015 at 10:46 pm #5078
Dan
- Topics: 6
- Replies: 197
- Total: 203
- Guardian Angel
@dan
Hi.
After a long planning and worrying time I finally got my Twinvir tablets. I plan to start tomorrow morning 3rd of December.
My results now:
F1-F2
Alt 90
VL 400k
Treatment naive.
Plan to go for 12 week.

Gen 1b, F1-F2. Naive.
Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
Starting VL 400000, Alt 49/AST 44
1 week VL 29, ALT 44/AST 30.
4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
7 weeks VL Detected, ALT 28, all other normal
8 weeks UND, 12 week UND, 24 week SVR UND
2 December 2015 at 10:48 pm #5079
LondonGirl
- Topics: 16
- Replies: 1,348
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- Guardian Angel
@londongirl
Dan, Do you mind me asking, what weight are you?
Good luck tomorrow .

GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
2 December 2015 at 11:04 pm #5081
zhuk
- Topics: 5
- Replies: 543
- Total: 548
- Guardian Angel
@zhuk
Great stuff Dan, looking forward to hearing about your journey.

And a good question LG, I’m interested to know as well.

GT1a since 1988, diagnosed 1990
F0, tx naive
VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 – 2.9
Started Mesochem sof/dac 12 weeks 01/01/2016
11/02/2016 – 6 weeks UNDETECTED
AST 26
ALT 26
2 December 2015 at 11:22 pm #5082
Dan
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- Total: 203
- Guardian Angel
@dan
Thank you.

I’m 91 kg at the moment and 6ft 3

Gen 1b, F1-F2. Naive.
Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
Starting VL 400000, Alt 49/AST 44
1 week VL 29, ALT 44/AST 30.
4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
7 weeks VL Detected, ALT 28, all other normal
8 weeks UND, 12 week UND, 24 week SVR UND
2 December 2015 at 11:33 pm #5083
zhuk
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- Guardian Angel
@zhuk
Other end of the scale to both LG & me then heh

You should do well with few sx, fingers crossed

GT1a since 1988, diagnosed 1990
F0, tx naive
VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 – 2.9
Started Mesochem sof/dac 12 weeks 01/01/2016
11/02/2016 – 6 weeks UNDETECTED
AST 26
ALT 26
2 December 2015 at 11:43 pm #5085
Alsdad
- Topics: 18
- Replies: 317
- Total: 335
- Guardian Angel
@alsdad
Congrats on getting the meds Dan. Did you have any joy with the stuck-in-the-muds at Manchester Royal wrt monitoring?
2 December 2015 at 11:57 pm #5087
Jolie
- Topics: 5
- Replies: 126
- Total: 131
- Guardian Angel
@jolie
Great Dan, congrats!
I started Sof/Dac last night, planned to start later this month but moment the meds came through the door I just swallowed them, could not resist…no more waiting,

Geno 3, Fibro 8.7 pKA, tx experinced in 2005 – Peg/Riba, relapsed.
Started tx 1/12/2015 with Indian Sofo & Chinese Dac.
5 weeks result all normal, ALT 18 – down from ALT 73 at the start of tx.
5 weeks HCV PCR RNA – UND. – down from 2 ML
9 weeks HCV PCR RNA – UND.
3 December 2015 at 12:00 am #5089
crazy8
- Topics: 0
- Replies: 49
- Total: 49
- Recovery Champion
@crazy8
GL with your treatment Dan!

GT 3, F3, Contracted 1993 Tx Naive
V/L 1,267,000 AST 67 ALT 65 6/10/15
commence Sof/Dac (Mesochem) 6/11/15
AST ALT normal 24/11 *
*V/L UNDETECTED 24/11*
3 December 2015 at 1:35 am #5097
Dan
- Topics: 6
- Replies: 197
- Total: 203
- Guardian Angel
@dan
Thank you All.

Alsdad- no, I have a hospital appointment next week, but doubt they will change their mind. You know what they like. I plan to ask them for bloods and after 4 weeks my GP. In the worst case we have PallMall. I’ll need your advice for that later, if you don’t mind.

Jolie – good luck to you too with your tx.

Gen 1b, F1-F2. Naive.
Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
Starting VL 400000, Alt 49/AST 44
1 week VL 29, ALT 44/AST 30.
4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
7 weeks VL Detected, ALT 28, all other normal
8 weeks UND, 12 week UND, 24 week SVR UND
3 December 2015 at 1:54 am #5099
Dan
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- Total: 203
- Guardian Angel
@dan
I’m trying to find if it is ok to take antihistamine tablets with Twinvir, as I need it to deal with my eczema.

Does anyone know if it is safe to take them on tx?

Gen 1b, F1-F2. Naive.
Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
Starting VL 400000, Alt 49/AST 44
1 week VL 29, ALT 44/AST 30.
4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
7 weeks VL Detected, ALT 28, all other normal
8 weeks UND, 12 week UND, 24 week SVR UND
3 December 2015 at 2:58 am #5102
zhuk
- Topics: 5
- Replies: 543
- Total: 548
- Guardian Angel
@zhuk
Check them out here Dan

http://www.hep-druginteractions.org/checker

GT1a since 1988, diagnosed 1990
F0, tx naive
VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 – 2.9
Started Mesochem sof/dac 12 weeks 01/01/2016
11/02/2016 – 6 weeks UNDETECTED
AST 26
ALT 26
3 December 2015 at 5:37 am #5115
Chejai
- Topics: 5
- Replies: 267
- Total: 272
- Guardian Angel
@chejai
Great news for you Dan, looking forward to following your journey

QLD Australia ‚òÄÔ∏è
G3a HCV 35 yrs Tx naive
Started Sof/Dac 13/01/16

Dec ’15
AST 70
ALT 89
GGT 124
Fibroscore 8.5
F1-F2
13 Feb’16 VL UND
AST 24
ALT 26
GGT 50H
3 December 2015 at 10:17 am #5155
Enkel
- Topics: 16
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- Total: 309
- Guardian Angel
@enkel
Dan,

Is is not a good idea to take antihistamine during treatment. Take as few other meds as possible.

Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured
3 December 2015 at 12:13 pm #5167
CJ
- Topics: 10
- Replies: 362
- Total: 372
- Guardian Angel
@cj
Good luck Dan, hope it all goes smoothly
x

J the young dragon slayer is:
HepC 1a since birth
Male aged 15
VL 2000000
Started Twinvir/ 10-11-15-then Sof/led.
NO sides so far !
after one week VL : 37
after 4 wks VL : UND !
EOT 2/2/16 UND.!
4 wks. post tx results….pending….
7/3/16 VL result : 4 week post tx: SVR !
12 weeks SVR !
24 wks SVR yeeaa!!
3 December 2015 at 12:14 pm #5168
CJ
- Topics: 10
- Replies: 362
- Total: 372
- Guardian Angel
@cj
Hi Joli,
Good luck to you too!
x

J the young dragon slayer is:
HepC 1a since birth
Male aged 15
VL 2000000
Started Twinvir/ 10-11-15-then Sof/led.
NO sides so far !
after one week VL : 37
after 4 wks VL : UND !
EOT 2/2/16 UND.!
4 wks. post tx results….pending….
7/3/16 VL result : 4 week post tx: SVR !
12 weeks SVR !
24 wks SVR yeeaa!!
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