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  • 21 December 2015 at 1:56 pm #6907
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    fixhepc.com/images/coa/NMI-NATA-Sofosbuvir-Certification.pdf

    fixhepc.com/images/coa/NMI-NATA-Ledipasvir-Certification.pdf

    The 1H NMR matches that for a sample of ledipasvir extracted from tablets of Twinvir™.

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    21 December 2015 at 2:19 pm #6911
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    How does this compare to the original Harvoni ?? Is it same or 95 % like the original ??

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    21 December 2015 at 2:24 pm #6912
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    100%

    92.7 IS LEDIPASVIR ACETONE

    Mean = 99.7%, s = 0.01%

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    21 December 2015 at 2:40 pm #6913
    Avatar photoDan
    • Guardian Angel
    • ★★★★★
    @dan

    Thank you Enkel.
    So I need to show the percentages from the Initial analysis part:
    Sof 99.7% and Led 99.7%?

    Do you store your tablets in the room?

    Gen 1b, F1-F2. Naive.
    Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
    Starting VL 400000, Alt 49/AST 44
    1 week VL 29, ALT 44/AST 30.
    4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
    7 weeks VL Detected, ALT 28, all other normal
    8 weeks UND, 12 week UND, 24 week SVR UND

    21 December 2015 at 2:43 pm #6914
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    Yes in temperature room under 30º C.

    99.7 for both, even the analysis of harvoni will not be 100%

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    21 December 2015 at 2:54 pm #6917
    Avatar photoDan
    • Guardian Angel
    • ★★★★★
    @dan

    Thanks :)

    Gen 1b, F1-F2. Naive.
    Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
    Starting VL 400000, Alt 49/AST 44
    1 week VL 29, ALT 44/AST 30.
    4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
    7 weeks VL Detected, ALT 28, all other normal
    8 weeks UND, 12 week UND, 24 week SVR UND

    21 December 2015 at 3:26 pm #6923
    Avatar photoLondonGirl
    • Guardian Angel
    • ★★★★★
    @londongirl

    Don’t forget the phrase “Supply chain integrity”
    and the GP Cheat Sheet :

    http://fixhepc.com/forum/forum-gp-cheat-sheet.html

    Good luck Dan

    GT1a Dec14 F2/8.7 VL 900000-2.5M
    Jan16 Hepcivir-L MonkMed/Redemption
    Baseline: VL 913575 Alt 76 Platelets low
    Wk2 VL1157 Alt 23
    DET Wk 8 VL 32 Alt19 ‘In the slow lane’
    June16 Fibro 5.7 F0/1 LIF 1.5
    Wk 11 VL<12 Alt 13 Det/Unq
    Extending tx 12 wks Mylan Sofo/Dac MonkMed
    Wk 14 VL <12 Det/Unq
    Wk 16 VL UNDETECTED
    Wk 22 + 4 Wks Sunprevir FixHepC
    Wk 24 UNDETECTED Alt 13
    Wk 12 post tx SVR12 Wk 26 SVR24
    Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC

    21 December 2015 at 8:26 pm #6978
    Avatar photoDan
    • Guardian Angel
    • ★★★★★
    @dan

    Hi. Good news!!!!
    Gp is happy to monitor my bloods, checked my blood pressure and ESG.

    He ordered all the blood tests, including the Viral load, but said that not sure if VL will be accepted.

    He will see me again in 4 weeks to order the next set of blood tests and see the progress.

    My 4 weeks will be next Wednesday. Should I wait until then or not.

    With Christmas coming up, do I need to stay away from sugar/cakes?

    Gen 1b, F1-F2. Naive.
    Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
    Starting VL 400000, Alt 49/AST 44
    1 week VL 29, ALT 44/AST 30.
    4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
    7 weeks VL Detected, ALT 28, all other normal
    8 weeks UND, 12 week UND, 24 week SVR UND

    21 December 2015 at 8:35 pm #6979
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    You showed him the test files of Twinvir?

    Are you feeling better now?

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    21 December 2015 at 9:04 pm #6981
    Avatar photoDan
    • Guardian Angel
    • ★★★★★
    @dan

    I printed them out, but he didn’t look at them. He said that he’s not done this before, but happy to support.

    Still on and off. I feel better over weekend, more rest at home. During the week is harder.

    Most of the time feel worse after lunch. Possibly this is when Sof clicks in

    Gen 1b, F1-F2. Naive.
    Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
    Starting VL 400000, Alt 49/AST 44
    1 week VL 29, ALT 44/AST 30.
    4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
    7 weeks VL Detected, ALT 28, all other normal
    8 weeks UND, 12 week UND, 24 week SVR UND

    21 December 2015 at 9:20 pm #6986
    Avatar photoLondonGirl
    • Guardian Angel
    • ★★★★★
    @londongirl

    Great news Dan – Yay – GPs ROCK :)
    So pleased for you.

    GT1a Dec14 F2/8.7 VL 900000-2.5M
    Jan16 Hepcivir-L MonkMed/Redemption
    Baseline: VL 913575 Alt 76 Platelets low
    Wk2 VL1157 Alt 23
    DET Wk 8 VL 32 Alt19 ‘In the slow lane’
    June16 Fibro 5.7 F0/1 LIF 1.5
    Wk 11 VL<12 Alt 13 Det/Unq
    Extending tx 12 wks Mylan Sofo/Dac MonkMed
    Wk 14 VL <12 Det/Unq
    Wk 16 VL UNDETECTED
    Wk 22 + 4 Wks Sunprevir FixHepC
    Wk 24 UNDETECTED Alt 13
    Wk 12 post tx SVR12 Wk 26 SVR24
    Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC

    21 December 2015 at 9:23 pm #6987
    Avatar photoDan
    • Guardian Angel
    • ★★★★★
    @dan

    Thanks LG.

    Gen 1b, F1-F2. Naive.
    Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
    Starting VL 400000, Alt 49/AST 44
    1 week VL 29, ALT 44/AST 30.
    4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
    7 weeks VL Detected, ALT 28, all other normal
    8 weeks UND, 12 week UND, 24 week SVR UND

    21 December 2015 at 11:08 pm #6996
    avatar876.jpegGaj
    • Guardian Angel
    • ★★★★★
    @gaj

    Great news Dan!

    Hmm, Xmas….stay away from sugar/cakes? Well we probably all should, even those without the virus, but a little bit of moderation should see us through I think. :P

    G

    G3a since ’78 – Dx ’12 – F4 (2xHCC)
    24wk Tx – PEG/Riba/Dac 2013 relapsed
    24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
    16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
    SVR7 – 22/06/17 UND
    SRV12 – 27/07/17 UND
    SVR24 – 26/10/17 UND
    :cheer: :cheer: :cheer:

    21 December 2015 at 11:17 pm #6998
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    Now whats wrong with sugar ? Is it not enough that I have Hep C ? LOL

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    24 December 2015 at 5:06 pm #7246
    Avatar photoDan
    • Guardian Angel
    • ★★★★★
    @dan

    Day 22
    Still don’t feel any big physical improvements, apart from sleep.

    I started to feel pain in my calf 3 days ago and it gets worse every day

    Gen 1b, F1-F2. Naive.
    Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
    Starting VL 400000, Alt 49/AST 44
    1 week VL 29, ALT 44/AST 30.
    4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
    7 weeks VL Detected, ALT 28, all other normal
    8 weeks UND, 12 week UND, 24 week SVR UND

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